Epigenetics - Global Market Outlook (2017-2023)

Epigenetics - Global Market Outlook (2017-2023)

  • Published: December 2017
  • ID: SMRC16870

According to Stratistics MRC,the Global Epigenetics Market is accounted for $752.8 million in 2016 and expected to grow at a CAGR of 14.0% to reach $1891.9 million by 2023. Growing prevalence of cancer and other chronic diseases are helping the market to compete across the globe. Some of the major factors that are influencing the market include growing technological advancements, rising R&D expenditure, growing usage for non-oncology diseases, improving collaborations between pharmaceutical, biotechnology companies & academic research institutes and increasing geriatric population base. However, huge equipment cost, lack of predictive markers, inefficiency in identification and validation of biomarkers, presence of complicated regulatory framework and shortage of skilled professional are hampering the market growth.

Based on Technology, DNA methylation can be classified as hyper and hypomethylation. Reduced representation bisulfite sequencing (RRBS) is a DNA wide methylation analysis technique for a combination of enrichment and modifying techniques. DNA methylation is also used as a biomarker for early cancer diagnosis. The FDA-approved epigenetic drugs are demethylating agents, and most of the diagnostic activity to date in epigenetics has focused on methylation markers.

Based on End User, with in the pharmaceutical sector, the therapeutic applications of epigenetics have fascinated a large and growing number of pharmaceutical and biopharmaceutical companies. Over 40 companies that are now active. Venture capital-funded companies in epigenetics include Constellation Pharmaceuticals and Syndax Pharmaceuticals.

North America dominated the overall revenue, due to the, increasing funds for R&D, growing collaborations between large pharmaceutical firms and demand for epigenetic drugs and diagnostic technologies. However, Asia-Pacific is anticipated to grow rapidly, due to high incidence of cancer, large prevalence of target diseases and rise in healthcare expenditure.

Some of the key players in Global Epigenetics market are Celgene Corporation, CellCentric Ltd, Chroma Therapeutics Ltd, Covaris Inc, DIAGENODE, INC., Ribimed Biotechnologies, Epigenomics AG, Epitherapeutics, Epizyme, Karus Therapeutics, Merck Millipore, Novartis International AG, Oncolys Biopharma Inc, OncoMethylome Sciences, Qiagen, Sigma-Aldrich Corporation, Syndax Pharmaceuticals and ZYMO RESEARCH CORPORATION (ZYMO).

Products Covered:
• Enzymes
• Reagents
• Kits
• Instruments and Consumables

Technologies Covered:
• Histone Methylation
• DNA Methylation
• Histone Acetylation
• Large noncoding RNA
• Chromatin structures
• MicroRNA Modification
• Other Technologies

Applications Covered:
• Cardiovascular Diseases
• Developmental Biology
• Immunology
• Metabolic Diseases
• Inflammatory Disease
• Oncology
• Other Applications

End Users Covered:
• Pharmaceutical
• Contract Research Organizations
• Academic and Research Institutes
• Biotechnology Companies

Regions Covered:

  • North America
    • US
    • Canada
    • Mexico
  • Europe
    • Germany
    • UK
    • Italy
    • France
    • Spain
    • Rest of Europe
  • Asia Pacific
    • Japan       
    • China       
    • India       
    • Australia 
    • New Zealand     
    • South Korea      
    • Rest of Asia Pacific   
  • South America
    • Argentina
    • Brazil
    • Chile
    • Rest of South America
  • Middle East & Africa
    • Saudi Arabia
    • UAE
    • Qatar
    • South Africa
    • Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country level segments
- Market share analysis of the top industry players
- Strategic recommendations for the new entrants
- Market forecasts for a minimum of 7 years of all the mentioned segments, sub segments and the regional markets
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

1 Executive Summary        
          
2 Preface 
        
 2.1 Abstract        
 2.2 Stake Holders       
 2.3 Research Scope       
 2.4 Research Methodology      
  2.4.1 Data Mining      
  2.4.2 Data Analysis      
  2.4.3 Data Validation      
  2.4.4 Research Approach      
 2.5 Research Sources       
  2.5.1 Primary Research Sources     
  2.5.2 Secondary Research Sources     
  2.5.3 Assumptions      
          
3 Market Trend Analysis       
 3.1 Introduction       
 3.2 Drivers        
 3.3 Restraints       
 3.4 Opportunities       
 3.5 Threats        
 3.6 Technology Analysis      
 3.7 Product Analysis       
 3.8 Application Analysis      
 3.9 End User Analysis       
 3.10 Emerging Markets       
 3.11 Futuristic Market Scenario      
          
4 Porters Five Force Analysis       
 4.1 Bargaining power of suppliers      
 4.2 Bargaining power of buyers      
 4.3 Threat of substitutes      
 4.4 Threat of new entrants      
 4.5 Competitive rivalry       
          
5 Global Epigenetics Market, By Product      
 5.1 Introduction       
 5.2 Enzymes         
  5.2.1 RNA-Modifying Enzymes     
   5.2.1.1 Reverse Transcriptase    
   5.2.1.2 RNA Ligases     
   5.2.1.2 Other RNA-modifying Enzymes   
  5.2.2 Protein-Modifying Enzymes     
   5.2.2.1 Acetylases     
   5.2.2.2 Methyltransferases     
  5.2.3 DNA-Modifying Enzymes     
   5.2.3.1 DNA Ligases     
   5.2.3.2 DNA Polymerases     
 5.3 Reagents        
  5.3.1 Primers       
  5.3.2 Magnetic Beads      
  5.3.3 Histones       
  5.3.4 Buffers       
  5.3.5 Antibodies      
  5.3.6 Other Epigenetics Reagents     
 5.4 Kits         
  5.4.1 5-HMC and 5-MC Analysis Kits     
  5.4.2 Bisulfite Conversion Kits     
  5.4.3 Chip-Seq Kits      
  5.4.4 RNA Sequencing Kits     
  5.4.5 Whole-Genome Amplification Kits    
  5.4.6 Methyltransferase assays     
  5.4.7 Histone Assays      
  5.4.8 Immunoprecipitation Kits     
  5.4.9 Other Epigenetics Kits     
 5.5 Instruments and Consumables      
  5.5.1 Mass Spectrometers     
  5.5.2 Next-Generation Sequencers     
  5.5.3 Qpcr Instruments      
  5.5.4 Sonicators      
  5.5.5 Other Instruments and Consumables    
          
6 Global Epigenetics Market, By Technology     
 6.1 Introduction       
 6.2 Histone Methylation      
 6.3 DNA Methylation        
 6.4 Histone Acetylation       
 6.5 Large noncoding RNA      
 6.6 Chromatin structures      
 6.7 MicroRNA Modification      
 6.8 Other Technologies       
          
7 Global Epigenetics Market, By Application     
 7.1 Introduction       
 7.2 Cardiovascular Diseases       
 7.3 Developmental Biology       
 7.4 Immunology        
 7.5 Metabolic Diseases        
 7.6 Inflammatory Disease      
 7.7 Oncology        
  7.7.1 Liquid Tumor      
  7.7.2 Solid Tumor      
 7.8 Other Applications       
          
8 Global Epigenetics Market, By End User      
 8.1 Introduction       
 8.2 Pharmaceutical       
 8.3 Contract Research Organizations     
 8.4 Academic and Research Institutes      
 8.5 Biotechnology Companies      
          
9 Global Epigenetics Market, By Geography     
 9.1 Introduction       
 9.2 North America       
  9.2.1 US       
  9.2.2 Canada       
  9.2.3 Mexico       
 9.3 Europe        
  9.3.1 Germany       
  9.3.2 UK       
  9.3.3 Italy       
  9.3.4 France       
  9.3.5 Spain       
  9.3.6 Rest of Europe      
 9.4 Asia Pacific       
  9.4.1 Japan       
  9.4.2 China       
  9.4.3 India       
  9.4.4 Australia       
  9.4.5 New Zealand      
  9.4.6 South Korea      
  9.4.7 Rest of Asia Pacific      
 9.5 South America       
  9.5.1 Argentina      
  9.5.2 Brazil       
  9.5.3 Chile       
  9.5.4 Rest of South America     
 9.6 Middle East & Africa      
  9.6.1 Saudi Arabia      
  9.6.2 UAE       
  9.6.3 Qatar       
  9.6.4 South Africa      
  9.6.5 Rest of Middle East & Africa     
          
10 Key Developments        
 10.1 Agreements, Partnerships, Collaborations and Joint Ventures   
 10.2 Acquisitions & Mergers      
 10.3 New Product Launch      
 10.4 Expansions       
 10.5 Other Key Strategies      
          
11 Company Profiling  
      
 11.1 Celgene Corporation      
 11.2 CellCentric Ltd       
 11.3 Chroma Therapeutics Ltd,       
 11.4 Covaris Inc       
 11.5 DIAGENODE, INC.       
 11.6
Ribomed      
 11.7 Epigenomics AG       
 11.8 Epitherapeutics       
 11.9 Epizyme        
 11.10 Karus Therapeutics       
 11.11 Merck Millipore       
 11.12 Novartis International AG      
 11.13 Oncolys Biopharma Inc      
 11.14 OncoMethylome Sciences      
 11.15 Qiagen        
 11.16 Sigma-Aldrich Corporation      
 11.17 Syndax Pharmaceuticals      
 11.18 ZYMO RESEARCH CORPORATION (ZYMO)     


List of Tables          
1 Global Epigenetics Market Outlook, By Region (2014-2023) ($MN)   
2 Global Epigenetics Market Outlook, By Product (2014-2023) ($MN)   
3 Global Epigenetics Market Outlook, By Enzymes (2014-2023) ($MN)   
4 Global Epigenetics Market Outlook, By RNA-Modifying Enzymes (2014-2023) ($MN)  
5 Global Epigenetics Market Outlook, By Protein-Modifying Enzymes (2014-2023) ($MN) 
6 Global Epigenetics Market Outlook, By DNA-Modifying Enzymes (2014-2023) ($MN) 
7 Global Epigenetics Market Outlook, By Reagents (2014-2023) ($MN)   
8 Global Epigenetics Market Outlook, By Primers (2014-2023) ($MN)   
9 Global Epigenetics Market Outlook, By Magnetic Beads (2014-2023) ($MN)  
10 Global Epigenetics Market Outlook, By Histones (2014-2023) ($MN)   
11 Global Epigenetics Market Outlook, By Buffers (2014-2023) ($MN)   
12 Global Epigenetics Market Outlook, By Antibodies (2014-2023) ($MN)   
13 Global Epigenetics Market Outlook, By Other Epigenetics Reagents (2014-2023) ($MN) 
14 Global Epigenetics Market Outlook, By Kits (2014-2023) ($MN)    
15 Global Epigenetics Market Outlook, By 5-HMC and 5-MC Analysis Kits (2014-2023) ($MN) 
16 Global Epigenetics Market Outlook, By Bisulfite Conversion Kits (2014-2023) ($MN)  
17 Global Epigenetics Market Outlook, By Chip-Seq Kits (2014-2023) ($MN)   
18 Global Epigenetics Market Outlook, By RNA Sequencing Kits (2014-2023) ($MN)  
19 Global Epigenetics Market Outlook, By Whole-Genome Amplification Kits (2014-2023) ($MN) 
20 Global Epigenetics Market Outlook, By Methyltransferase assays (2014-2023) ($MN) 
21 Global Epigenetics Market Outlook, By Histone Assays (2014-2023) ($MN)  
22 Global Epigenetics Market Outlook, By Immunoprecipitation Kits (2014-2023) ($MN) 
23 Global Epigenetics Market Outlook, By Other Epigenetics Kits (2014-2023) ($MN)  
24 Global Epigenetics Market Outlook, By Instruments and Consumables (2014-2023) ($MN) 
25 Global Epigenetics Market Outlook, By Mass Spectrometers (2014-2023) ($MN)  
26 Global Epigenetics Market Outlook, By Next-Generation Sequencers (2014-2023) ($MN) 
27 Global Epigenetics Market Outlook, By Qpcr Instruments (2014-2023) ($MN)  
28 Global Epigenetics Market Outlook, By Sonicators (2014-2023) ($MN)   
29 Global Epigenetics Market Outlook, By Other Instruments and Consumables (2014-2023) ($MN)
30 Global Epigenetics Market Outlook, By Technology (2014-2023) ($MN)   
31 Global Epigenetics Market Outlook, By Histone Methylation (2014-2023) ($MN)  
32 Global Epigenetics Market Outlook, By DNA Methylation (2014-2023) ($MN)  
33 Global Epigenetics Market Outlook, By Histone Acetylation (2014-2023) ($MN)  
34 Global Epigenetics Market Outlook, By Large noncoding RNA (2014-2023) ($MN)  
35 Global Epigenetics Market Outlook, By Chromatin structures (2014-2023) ($MN)  
36 Global Epigenetics Market Outlook, By MicroRNA Modification (2014-2023) ($MN)  
37 Global Epigenetics Market Outlook, By Other Technologies (2014-2023) ($MN)  
38 Global Epigenetics Market Outlook, By Application (2014-2023) ($MN)   
39 Global Epigenetics Market Outlook, By Cardiovascular Diseases (2014-2023) ($MN)  
40 Global Epigenetics Market Outlook, By Developmental Biology (2014-2023) ($MN)  
41 Global Epigenetics Market Outlook, By Immunology (2014-2023) ($MN)   
42 Global Epigenetics Market Outlook, By Metabolic Diseases (2014-2023) ($MN)  
43 Global Epigenetics Market Outlook, By Inflammatory Disease (2014-2023) ($MN)  
44 Global Epigenetics Market Outlook, By Oncology (2014-2023) ($MN)   
45 Global Epigenetics Market Outlook, By Liquid Tumor (2014-2023) ($MN)   
46 Global Epigenetics Market Outlook, By Solid Tumor (2014-2023) ($MN)   
47 Global Epigenetics Market Outlook, By Other Applications (2014-2023) ($MN)  
48 Global Epigenetics Market Outlook, By End User (2014-2023) ($MN)   
49 Global Epigenetics Market Outlook, By Pharmaceutical (2014-2023) ($MN)  
50 Global Epigenetics Market Outlook, By Contract Research Organizations (2014-2023) ($MN) 
51 Global Epigenetics Market Outlook, By Academic and Research Institutes (2014-2023) ($MN) 
52 Global Epigenetics Market Outlook, By Biotechnology Companies (2014-2023) ($MN) 

Note: North America, Europe, Asia Pacific, South America and Middle East are represented in above manner.

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