Bone Metastasis Market

Bone Metastasis Market

Bone Metastasis Market Forecasts to 2028 - Global Analysis By Product (Targeted Therapy Agents, Bone Building Medications, Pain Relievers and Other Products), By Diagnosis (Blood Test, Biopsy, Imaging and Other Diagnosis), By Treatment, By Type, By Origin, By End User and By Geography

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Published: 2023 ID: SMRC23271

This report covers the impact of COVID-19 on this global market

According to Stratistics MRC, the Global Bone Metastasis Market is accounted for $19.7 billion in 2022 and is expected to reach $37.4 billion by 2028 growing at a CAGR of 11.3% during the forecast period. In basic terms, bone metastasis (also known as bone mets) happens when cancer cells fragment from a primary tumor located anywhere else in the body, move through the bloodstream or lymph system to a portion of the bone, and then develop into metastatic cancer cells. A primary bone tumor, which typically begins in the bone, is different from this. When these cancer cells invade the bone, they release chemicals that either activate osteoblasts or osteoclasts. Osteoclasts result in bone disintegration without new bone formation, which weakens the bones.

According to Cancer Research U.K, in males, prostate cancer is the most common cancer, with around 47,200 new cases each year.

Market Dynamics:


High prevalence of cancer

The primary reasons driving the global market for treatments for bone metastasis are the high prevalence and rising incidence rates of the causes of bone metastasis, particularly breast cancer and prostate cancer. Each year, more than 2.1 million women undergo a breast cancer diagnosis, according to the World Health Organization (WHO). Globocan estimates that 1,276,106 new cases of prostate cancer were diagnosed worldwide in 2018. The increasing prevalence and rising incidence rates of bone metastasis around the world are hence one of the key factors anticipated to drive the market for the treatment of bone metastasis during the projected timeframe.


High treatment cost

A multidisciplinary approach is necessary for the management of patients with metastatic bone disease to ensure adequate diagnostic evaluation and therapy planning. To maximize treatment outcomes, a multi-modal treatment strategy that combines medical therapy, radiation, and surgery would be beneficial. Surgery for metastatic disease aims to reduce pain, regain functional independence, and enhance patients' overall quality of life. However, complications and high treatment costs may limit market growth.


Technological advancements

Bone metastases, which frequently cause intense pain, pathological fractures, and nerve damage in cancer patients, have a major negative influence on quality of life and life expectancy. Even though current therapeutic options are often just palliative and not curative, surgery is still the gold standard for treating bone metastases. The primary objective of surgical intervention is to replace the damaged bone with a bioimplant, which can be made from materials derived from diverse sources and fabricated utilizing a range of techniques that have evolved through time in accordance with clinical requirements.


Untapped emerging markets and lack of healthcare services

The untapped emerging markets, however, hinder the market from expanding. Within the projected period, it is also anticipated that the lack of healthcare services in low-income nations will restrain market expansion. The Food and Drug Administration's (FDA) slow drug approval process for cancer treatments is another significant issue limiting the growth of the bone metastasis market. Additionally, the market revenue growth of bone metastasis is hampered by the lack of diagnostic methods for the disorder.

Covid-19 Impact:

The global COVID outbreak has placed cancer patients in considerable jeopardy. Leading hospitals and research facilities advise cancer patients to stay at home until COVID infections disappear due to concerns about their poor immunity levels. The postponement of operations, radiation treatments, and chemotherapy sessions has disrupted the treatment plans of several cancer patients worldwide. Cancer patients may have lowered immunity, making them more vulnerable to contracting the virus. And if it happens, the patient will pass away very quickly. Doctors are therefore taking all necessary measures to keep kids safe, at least from COVID.

The osteolytic bone metastasis segment is expected to be the largest during the forecast period

Osteolytic Bone Metastasis is witnessed to hold the dominant share over the forecast period. The most common type of bone metastasis in cancer patients is osteolytic metastasis. Although a localized response to bone growth is also present, the primary lesion is lytic and destructive. Osteolytic metastases can form in solid tumors such as breast cancer, prostate cancer, thyroid cancer, lung cancer, and renal cancer.

The biopsy segment is expected to have the highest CAGR during the forecast period

Biopsy segment is anticipated to have lucrative growth over the projected period. In order to detect the presence of cancer or other abnormal cells, bone samples are taken during surgery or using a particular biopsy needle. A bone biopsy involves the outer layers of the bone, as opposed to a bone marrow biopsy, which involves the interior portion of the bone. These elements are augmenting the segments growth.

Region with largest share:

North America is predicted to hold the largest share throughout the domination period due to the region's expanding breast cancer prevalence and the existence of a highly developed healthcare industry. However, the region has witnessed an increase in cancer cases as a result of the consumption of highly processed foods and sugary beverages, obesity, Type 2 diabetes, sedentary lifestyles, and rising alcohol consumption. It is projected that rising market demand will result from expanding research on cancer stem cells.

Region with highest CAGR:

Asia-Pacific region is projected to have a lucrative CAGR throughout the anticipated period due to a booming healthcare industry and increase in the number of patients with bone metastases, government initiatives to raise awareness, and an increase in demand for the therapy. Additionally, the existence of a significant population in the area is one of the major factors projected to positively influence the growth of the bone metastasis market. Moreover, china is accounted to be responsible for 50% of all cancer cases in the Asia-Pacific region.

Key players in the market

Some of the key players in Bone Metastasis market include Amgen Inc. , Bayer, BeiGene, Centus Biotherapeutics Ltd, Eli Lilly and Company, General Electric, Koninklijke Philips N.V., Medtronic, Merck & Co., Inc., Novartis Ag, Novicure Biotechnology, Oncobone Ltd, Pfizer Inc, Pharmalucence Inc, Q Biomed Inc., Siemens Ag And Toshiba Corporation.

Key Developments:

In March 2022, FDA approved Novartis Pluvicto as the first targeted radioligand therapy for the management of metastatic castration-resistant prostate cancer.

In June 2021, Bayer announced that it had reached a deal to purchase PSMA Therapeutics Inc. and Noria Therapeutics Inc. The acquisition increases the scope of Bayer's current oncology portfolio.

Products Covered:
• Targeted Therapy Agents
• Bone Building Medications
• Pain Relievers
• Other Products

Diagnosis Covered:
• Blood Test
• Biopsy
• Imaging
• Other Diagnosis

Treatments Covered:
• Medical Therapies
• Surgery
• Medication

Types Covered:
• Mixed Bone Metastasis
• Osteoblastic Bone Metastasis
• Osteolytic Bone Metastasis
• Other Types

Origins Covered:
• Prostate
• Kidney
• Thyroid
• Lung
• Breast

End Users Covered:
• Ambulatory Surgical Centers
• Pharmacies
• Diagnostic Centers
• Hospital & Clinics
• Other End Users

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions

3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 End User Analysis
3.8 Emerging Markets
3.9 Impact of Covid-19

4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 Global Bone Metastasis Market, By Product
5.1 Introduction
5.2 Targeted Therapy Agents
5.3 Bone Building Medications
5.4 Pain Relievers
5.5 Other Products

6 Global Bone Metastasis Market, By Diagnosis
6.1 Introduction
6.2 Blood Test
6.3 Biopsy
6.4 Imaging
6.4.1 Positron Emission Tomography
6.4.2 Magnetic Resonance Imaging
6.4.3 Computerized Tomography
6.4.4 Bone Scintigraphy
6.4.5 X-Ray
6.5 Other Diagnosis

7 Global Bone Metastasis Market, By Treatment
7.1 Introduction
7.2 Medical Therapies
7.2.1 Chemotherapy
7.2.2 Hormone Therapy
7.2.3 Targeted Therapy
7.2.4 Ablation Therapy Radiofrequency Ablation Cryoablation
7.3 Surgery
7.3.1 Kyphoplasty
7.3.2 Vertebroplasty
7.4 Medication
7.4.1 Pain Medications Morphine Ibuprofen
7.4.2 Bone-Building Medications Corticosteroids Bisphosphonates Medronate Pamidronate Teriparatide

8 Global Bone Metastasis Market, By Type
8.1 Introduction
8.2 Mixed Bone Metastasis
8.3 Osteoblastic Bone Metastasis
8.4 Osteolytic Bone Metastasis
8.5 Other Types

9 Global Bone Metastasis Market, By Origin
9.1 Introduction
9.2 Prostate
9.3 Kidney
9.4 Thyroid
9.5 Lung
9.6 Breast

10 Global Bone Metastasis Market, By End User
10.1 Introduction
10.2 Ambulatory Surgical Centers
10.3 Pharmacies
10.4 Diagnostic Centers
10.5 Hospital & Clinics
10.6 Other End Users

11 Global Bone Metastasis Market, By Geography
11.1 Introduction
11.2 North America
11.2.1 US
11.2.2 Canada
11.2.3 Mexico
11.3 Europe
11.3.1 Germany
11.3.2 UK
11.3.3 Italy
11.3.4 France
11.3.5 Spain
11.3.6 Rest of Europe
11.4 Asia Pacific
11.4.1 Japan
11.4.2 China
11.4.3 India
11.4.4 Australia
11.4.5 New Zealand
11.4.6 South Korea
11.4.7 Rest of Asia Pacific
11.5 South America
11.5.1 Argentina
11.5.2 Brazil
11.5.3 Chile
11.5.4 Rest of South America
11.6 Middle East & Africa
11.6.1 Saudi Arabia
11.6.2 UAE
11.6.3 Qatar
11.6.4 South Africa
11.6.5 Rest of Middle East & Africa

12 Key Developments
12.1 Agreements, Partnerships, Collaborations and Joint Ventures
12.2 Acquisitions & Mergers
12.3 New Product Launch
12.4 Expansions
12.5 Other Key Strategies

13 Company Profiling
13.1 Amgen Inc.
13.2 Bayer
13.3 BeiGene
13.4 Centus Biotherapeutics Ltd
13.5 Eli Lilly and Company
13.6 General Electric
13.7 Koninklijke Philips N.V.
13.8 Medtronic
13.9 Merck & Co., Inc.
13.10 Novartis Ag
13.11 Novicure Biotechnology
13.12 Oncobone Ltd
13.13 Pfizer Inc
13.14 Pharmalucence Inc
13.15 Q Biomed Inc.
13.16 Siemens Ag
13.17 Toshiba Corporation

List of Tables
1 Global Bone Metastasis Market Outlook, By Region (2020-2028) ($MN)
2 Global Bone Metastasis Market Outlook, By Product (2020-2028) ($MN)
3 Global Bone Metastasis Market Outlook, By Targeted Therapy Agents (2020-2028) ($MN)
4 Global Bone Metastasis Market Outlook, By Bone Building Medications (2020-2028) ($MN)
5 Global Bone Metastasis Market Outlook, By Pain Relievers (2020-2028) ($MN)
6 Global Bone Metastasis Market Outlook, By Other Products (2020-2028) ($MN)
7 Global Bone Metastasis Market Outlook, By Diagnosis (2020-2028) ($MN)
8 Global Bone Metastasis Market Outlook, By Blood Test (2020-2028) ($MN)
9 Global Bone Metastasis Market Outlook, By Biopsy (2020-2028) ($MN)
10 Global Bone Metastasis Market Outlook, By Imaging (2020-2028) ($MN)
11 Global Bone Metastasis Market Outlook, By Positron Emission Tomography (2020-2028) ($MN)
12 Global Bone Metastasis Market Outlook, By Magnetic Resonance Imaging (2020-2028) ($MN)
13 Global Bone Metastasis Market Outlook, By Computerized Tomography (2020-2028) ($MN)
14 Global Bone Metastasis Market Outlook, By Bone Scintigraphy (2020-2028) ($MN)
15 Global Bone Metastasis Market Outlook, By X-Ray (2020-2028) ($MN)
16 Global Bone Metastasis Market Outlook, By Other Diagnosis (2020-2028) ($MN)
17 Global Bone Metastasis Market Outlook, By Treatment (2020-2028) ($MN)
18 Global Bone Metastasis Market Outlook, By Medical Therapies (2020-2028) ($MN)
19 Global Bone Metastasis Market Outlook, By Chemotherapy (2020-2028) ($MN)
20 Global Bone Metastasis Market Outlook, By Hormone Therapy (2020-2028) ($MN)
21 Global Bone Metastasis Market Outlook, By Targeted Therapy (2020-2028) ($MN)
22 Global Bone Metastasis Market Outlook, By Ablation Therapy (2020-2028) ($MN)
23 Global Bone Metastasis Market Outlook, By Surgery (2020-2028) ($MN)
24 Global Bone Metastasis Market Outlook, By Kyphoplasty (2020-2028) ($MN)
25 Global Bone Metastasis Market Outlook, By Vertebroplasty (2020-2028) ($MN)
26 Global Bone Metastasis Market Outlook, By Medication (2020-2028) ($MN)
27 Global Bone Metastasis Market Outlook, By Pain Medications (2020-2028) ($MN)
28 Global Bone Metastasis Market Outlook, By Bone-Building Medications (2020-2028) ($MN)
29 Global Bone Metastasis Market Outlook, By Type (2020-2028) ($MN)
30 Global Bone Metastasis Market Outlook, By Mixed Bone Metastasis (2020-2028) ($MN)
31 Global Bone Metastasis Market Outlook, By Osteoblastic Bone Metastasis (2020-2028) ($MN)
32 Global Bone Metastasis Market Outlook, By Osteolytic Bone Metastasis (2020-2028) ($MN)
33 Global Bone Metastasis Market Outlook, By Other Types (2020-2028) ($MN)
34 Global Bone Metastasis Market Outlook, By Origin (2020-2028) ($MN)
35 Global Bone Metastasis Market Outlook, By Prostate (2020-2028) ($MN)
36 Global Bone Metastasis Market Outlook, By Kidney (2020-2028) ($MN)
37 Global Bone Metastasis Market Outlook, By Thyroid (2020-2028) ($MN)
38 Global Bone Metastasis Market Outlook, By Lung (2020-2028) ($MN)
39 Global Bone Metastasis Market Outlook, By Breast (2020-2028) ($MN)
40 Global Bone Metastasis Market Outlook, By End User (2020-2028) ($MN)
41 Global Bone Metastasis Market Outlook, By Ambulatory Surgical Centers (2020-2028) ($MN)
42 Global Bone Metastasis Market Outlook, By Pharmacies (2020-2028) ($MN)
43 Global Bone Metastasis Market Outlook, By Diagnostic Centers (2020-2028) ($MN)
44 Global Bone Metastasis Market Outlook, By Hospital & Clinics (2020-2028) ($MN)
45 Global Bone Metastasis Market Outlook, By Other End Users (2020-2028) ($MN)

Note: Tables for North America, Europe, Asia Pacific, South America and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.

Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.

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