Cryo Electron Microscope Market
Cryo-electron Microscope Market Forecasts to 2030 - Global Analysis By Product (Instruments, Software and Services), Voltage (120 KV, 200 KV and 300 KV), Technology, Application, End User and By Geography
According to Stratistics MRC, the Global Cryo-electron Microscope Market is accounted for $1.35 billion in 2024 and is expected to reach $2.48 billion by 2030 growing at a CAGR of 10.7% during the forecast period. A cryo-electron microscope (Cryo-EM) is a powerful tool used in structural biology to visualize proteins, viruses, and other biological macromolecules at near-atomic resolution. This technique involves rapidly freezing samples at cryogenic temperatures to preserve their natural structure without the need for staining or fixing. Cryo-EM uses electron beams to image the samples, which are then reconstructed into detailed 3D models through advanced computational methods. This method is particularly valuable for studying complex molecular structures that are difficult to crystallize, providing critical insights into their function and mechanisms.
Market Dynamics:
Driver:
Growing demand for structural biology
The growing demand for structural biology is significantly driving the cryo-electron microscope (cryo-EM) market. Structural biology requires detailed visualization of biomolecular structures to understand their functions and interactions. Cryo-EM allows scientists to observe these structures at near-atomic resolution, facilitating breakthroughs in drug discovery, disease research, and biotechnology. The precision and efficiency of cryo-EM in resolving complex biological molecules are unmatched, making it an indispensable tool in modern structural biology.
Restraint:
Maintenance and operational costs
The cryo-electron microscope (Cryo-EM) market is significantly restrained by high maintenance and operational costs. These costs include the need for regular calibration, expensive consumables like liquid nitrogen, and specialized maintenance services that require skilled technicians. Additionally, the microscopes demand a controlled environment, adding to the costs of facilities and utilities. The complexity of the equipment necessitates ongoing training for operators, further increasing operational expenses. These financial burdens can deter smaller institutions and research centers from adopting cryo-EM technology.
Opportunity:
Expansion into new application areas
The expansion into new application areas presents a significant opportunity for the cryo-electron microscope (cryo-EM) market. Cryo-EM is increasingly being utilized in diverse fields such as structural biology, materials science, and nanotechnology. Its ability to provide high-resolution, three-dimensional images of biomolecules and complex materials at near-atomic resolutions makes it invaluable for drug discovery, virology research, and the development of novel nanomaterials. The versatility of cryo-EM in addressing complex scientific questions across various domains underscores its expanding application potential.
Threat:
Technical complexity
The technical complexity threat in the cryo-electron microscope (cryo-EM) market arises from the intricate design and sophisticated operation of these instruments. Cryo-EM systems require advanced knowledge for setup, maintenance, and operation, limiting their use to highly specialized personnel. Additionally, the integration of cryogenics, electron optics, and imaging technology demands significant expertise in multiple scientific domains. The high cost and need for regular calibration further complicate accessibility, posing challenges for widespread adoption in less-resourced laboratories.
Covid-19 Impact:
The COVID-19 pandemic significantly impacted the cryo-electron microscope (Cryo-EM) market by accelerating its demand and adoption in research and diagnostic applications. The urgent need to understand the SARS-CoV-2 virus structure and develop vaccines prompted increased investment in advanced imaging technologies like Cryo-EM. Many research institutions and pharmaceutical companies expanded their cryo-EM facilities to facilitate rapid virus and protein structure analysis. Consequently, the market experienced growth despite disruptions in supply chains and manufacturing due to lockdowns.
The nuclear magnetic resonance (NMR) microscopy segment is expected to be the largest during the forecast period
The growth of nuclear magnetic resonance (NMR) microscopy within the cryo-electron microscope market stems from its unique ability to provide high-resolution structural information about biological molecules in their native states. NMR complements cryo-EM by offering insights into dynamic processes and molecular interactions at the atomic level. This synergy enables researchers to gain a comprehensive understanding of complex biological systems, driving demand for integrated solutions. Additionally, advancements in NMR technology, such as higher magnetic field strengths and improved sensitivity, enhance its compatibility with cryo-EM workflows, further fueling its adoption.
The Nanotechnology segment is expected to have the highest CAGR during the forecast period
Nanotechnology's expansion in the cryo-electron microscope (Cryo-EM) market is fueled by its unparalleled ability to visualize nanoscale structures with exceptional resolution. As researchers delve deeper into the realm of nanoscience, the demand for cryo-EM technology has surged. Its capability to study biological samples at cryogenic temperatures provides invaluable insights into molecular structures, aiding drug discovery and material science. Moreover, advancements in nanomaterial synthesis and characterization necessitate high-resolution imaging tools like Cryo-EM. This synergy between nanotechnology and cryo-EM is propelling the market's growth and fostering innovation in various scientific disciplines.
Region with largest share:
The North American region has experienced significant growth in the cryo-electron microscope market due to several factors. There's a strong presence of leading pharmaceutical and biotechnology companies in the region, driving demand for advanced imaging technologies for drug discovery and development. Additionally, academic and research institutions in North America have been actively adopting cryo-EM for structural biology studies, further boosting market growth. The region's robust infrastructure, technological advancements, and favorable regulatory environment also contribute to the expansion of the cryo-EM market. Moreover, collaborations between industry players and research organizations foster innovation and accelerate market penetration.
Region with highest CAGR:
The Asia-Pacific region has witnessed significant growth in the Cryo-electron Microscope market due to several factors. Increased investment in research and development activities across various scientific disciplines has propelled the demand for advanced imaging technologies like cryo-electron microscopy. Rising adoption of cryo-EM techniques in pharmaceutical and biotechnology industries for drug discovery and structural biology studies has further stimulated market growth. Additionally, the presence of key market players expanding their operations in the region, coupled with government initiatives promoting scientific research, has fueled market expansion.
Key players in the market
Some of the key players in Cryo-electron Microscope market include AstraZeneca PLC, Carl Zeiss AG, Charles River Laboratories International, Inc., Delmic B.V., Electron Microscopy Sciences, Gatan, Inc., Hitachi High-Tech Corporation, Intertek Group PLC, Jena Bioscience GmbH, Jeol Ltd., Judges Scientific PLC, Leica Microsystems by Danaher Corporation, NanoImaging Services, Inc., Spectris PLC, SPT Labtech Ltd. and Thermo Fisher Scientific Inc.
Key Developments:
In June 2024, US lab equipment and services business Thermo Fisher Scientific has opened a new clinical and commercial ultra-cold facility in Bleiswijk, Netherlands. The new site specialises in ambient to cryogenic storage, clinical and commercial packaging, labelling and distribution, and clinical qualified person release services.
In April 2024, Total Quality Assurance (TQA) provider Intertek has entered a strategic partnership with software company Trace For Good to launch a software as a service (SaaS) platform to improve traceability and sustainability in textile and apparel supply chains. The platform’s feature is said to include supply chain mapping and traceability at the product level, verification of claims and documents, supplier risk assessments, and support in eco-design and Life Cycle Assessment.
Products Covered:
• Instruments
• Software
• Services
Voltages Covered:
• 120 KV
• 200 KV
• 300 KV
Technologies Covered:
• Scanning Electron Microscopy (SEM)
• Transmission Electron Microscopy (TEM)
• Nuclear Magnetic Resonance (NMR) Microscopy
• Single Particle Analysis
• Cryo-electron Tomography
• Electron Crystallography
Applications Covered:
• Nanotechnology
• Semiconductor
• Lifesciences
• Material Science
• Biological Science
• Disease Diagnosis and Pathology
• Toxicology Studies
• Preclinical and Clinical Studies
• Cancer Research
• Cell and Gene Therapy
• Vaccines
End Users Covered:
• Pharmaceutical & Biotechnology Companies
• Contract Research Organization
• Research Laboratories & Institutes
• Forensic & Diagnostic Laboratories
• Other End Users
Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa
What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2022, 2023, 2024, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements
Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances
Table of Contents
1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Technology Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Cryo-electron Microscope Market, By Product
5.1 Introduction
5.2 Instruments
5.2.1 Semi Automated Instruments
5.2.2 Fully Automated Instruments
5.3 Software
5.4 Services
6 Global Cryo-electron Microscope Market, By Voltage
6.1 Introduction
6.2 120 KV
6.3 200 KV
6.4 300 KV
7 Global Cryo-electron Microscope Market, By Technology
7.1 Introduction
7.2 Scanning Electron Microscopy (SEM)
7.3 Transmission Electron Microscopy (TEM)
7.4 Nuclear Magnetic Resonance (NMR) Microscopy
7.5 Single Particle Analysis
7.6 Cryo-electron Tomography
7.7 Electron Crystallography
7.7.1 Structure–Function Studies
7.7.2 Inorganic Crystals Studies
8 Global Cryo-electron Microscope Market, By Application
8.1 Introduction
8.2 Nanotechnology
8.3 Semiconductor
8.4 Lifesciences
8.5 Material Science
8.6 Biological Science
8.7 Disease Diagnosis and Pathology
8.8 Toxicology Studies
8.9 Preclinical and Clinical Studies
8.10 Cancer Research
8.11 Cell and Gene Therapy
8.12 Vaccines
9 Global Cryo-electron Microscope Market, By End User
9.1 Introduction
9.2 Pharmaceutical & Biotechnology Companies
9.3 Contract Research Organization
9.4 Research Laboratories & Institutes
9.5 Forensic & Diagnostic Laboratories
9.6 Other End Users
10 Global Cryo-electron Microscope Market, By Geography
10.1 Introduction
10.2 North America
10.2.1 US
10.2.2 Canada
10.2.3 Mexico
10.3 Europe
10.3.1 Germany
10.3.2 UK
10.3.3 Italy
10.3.4 France
10.3.5 Spain
10.3.6 Rest of Europe
10.4 Asia Pacific
10.4.1 Japan
10.4.2 China
10.4.3 India
10.4.4 Australia
10.4.5 New Zealand
10.4.6 South Korea
10.4.7 Rest of Asia Pacific
10.5 South America
10.5.1 Argentina
10.5.2 Brazil
10.5.3 Chile
10.5.4 Rest of South America
10.6 Middle East & Africa
10.6.1 Saudi Arabia
10.6.2 UAE
10.6.3 Qatar
10.6.4 South Africa
10.6.5 Rest of Middle East & Africa
11 Key Developments
11.1 Agreements, Partnerships, Collaborations and Joint Ventures
11.2 Acquisitions & Mergers
11.3 New Product Launch
11.4 Expansions
11.5 Other Key Strategies
12 Company Profiling
12.1 AstraZeneca PLC
12.2 Carl Zeiss AG
12.3 Charles River Laboratories International, Inc.
12.4 Delmic B.V.
12.5 Electron Microscopy Sciences
12.6 Gatan, Inc.
12.7 Hitachi High-Tech Corporation
12.8 Intertek Group PLC
12.9 Jena Bioscience GmbH
12.10 Jeol Ltd.
12.11 Judges Scientific PLC
12.12 Leica Microsystems by Danaher Corporation
12.13 NanoImaging Services, Inc.
12.14 Spectris PLC
12.15 SPT Labtech Ltd.
12.16 Thermo Fisher Scientific Inc.
List of Tables
1 Global Cryo-electron Microscope Market Outlook, By Region (2022-2030) ($MN)
2 Global Cryo-electron Microscope Market Outlook, By Product (2022-2030) ($MN)
3 Global Cryo-electron Microscope Market Outlook, By Instruments (2022-2030) ($MN)
4 Global Cryo-electron Microscope Market Outlook, By Semi Automated Instruments (2022-2030) ($MN)
5 Global Cryo-electron Microscope Market Outlook, By Fully Automated Instruments (2022-2030) ($MN)
6 Global Cryo-electron Microscope Market Outlook, By Software (2022-2030) ($MN)
7 Global Cryo-electron Microscope Market Outlook, By Services (2022-2030) ($MN)
8 Global Cryo-electron Microscope Market Outlook, By Voltage (2022-2030) ($MN)
9 Global Cryo-electron Microscope Market Outlook, By 120 KV (2022-2030) ($MN)
10 Global Cryo-electron Microscope Market Outlook, By 200 KV (2022-2030) ($MN)
11 Global Cryo-electron Microscope Market Outlook, By 300 KV (2022-2030) ($MN)
12 Global Cryo-electron Microscope Market Outlook, By Technology (2022-2030) ($MN)
13 Global Cryo-electron Microscope Market Outlook, By Scanning Electron Microscopy (SEM) (2022-2030) ($MN)
14 Global Cryo-electron Microscope Market Outlook, By Transmission Electron Microscopy (TEM) (2022-2030) ($MN)
15 Global Cryo-electron Microscope Market Outlook, By Nuclear Magnetic Resonance (NMR) Microscopy (2022-2030) ($MN)
16 Global Cryo-electron Microscope Market Outlook, By Single Particle Analysis (2022-2030) ($MN)
17 Global Cryo-electron Microscope Market Outlook, By Cryo-electron Tomography (2022-2030) ($MN)
18 Global Cryo-electron Microscope Market Outlook, By Single Particle Imaging (2022-2030) ($MN)
19 Global Cryo-electron Microscope Market Outlook, By Reconstruction (2022-2030) ($MN)
20 Global Cryo-electron Microscope Market Outlook, By Electron Crystallography (2022-2030) ($MN)
21 Global Cryo-electron Microscope Market Outlook, By Structure–Function Studies (2022-2030) ($MN)
22 Global Cryo-electron Microscope Market Outlook, By Inorganic Crystals Studies (2022-2030) ($MN)
23 Global Cryo-electron Microscope Market Outlook, By Application (2022-2030) ($MN)
24 Global Cryo-electron Microscope Market Outlook, By Nanotechnology (2022-2030) ($MN)
25 Global Cryo-electron Microscope Market Outlook, By Semiconductor (2022-2030) ($MN)
26 Global Cryo-electron Microscope Market Outlook, By Lifesciences (2022-2030) ($MN)
27 Global Cryo-electron Microscope Market Outlook, By Material Science (2022-2030) ($MN)
28 Global Cryo-electron Microscope Market Outlook, By Biological Science (2022-2030) ($MN)
29 Global Cryo-electron Microscope Market Outlook, By Disease Diagnosis and Pathology (2022-2030) ($MN)
30 Global Cryo-electron Microscope Market Outlook, By Toxicology Studies (2022-2030) ($MN)
31 Global Cryo-electron Microscope Market Outlook, By Preclinical and Clinical Studies (2022-2030) ($MN)
32 Global Cryo-electron Microscope Market Outlook, By Cancer Research (2022-2030) ($MN)
33 Global Cryo-electron Microscope Market Outlook, By Cell and Gene Therapy (2022-2030) ($MN)
34 Global Cryo-electron Microscope Market Outlook, By Vaccines (2022-2030) ($MN)
35 Global Cryo-electron Microscope Market Outlook, By End User (2022-2030) ($MN)
36 Global Cryo-electron Microscope Market Outlook, By Pharmaceutical & Biotechnology Companies (2022-2030) ($MN)
37 Global Cryo-electron Microscope Market Outlook, By Contract Research Organization (2022-2030) ($MN)
38 Global Cryo-electron Microscope Market Outlook, By Research Laboratories & Institutes (2022-2030) ($MN)
39 Global Cryo-electron Microscope Market Outlook, By Forensic & Diagnostic Laboratories (2022-2030) ($MN)
40 Global Cryo-electron Microscope Market Outlook, By Other End Users (2022-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
List of Figures
RESEARCH METHODOLOGY
We at ‘Stratistics’ opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.
Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.
Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.
Data Mining
The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.
Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.
Data Analysis
From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:
- Product Lifecycle Analysis
- Competitor analysis
- Risk analysis
- Porters Analysis
- PESTEL Analysis
- SWOT Analysis
The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.
Data Validation
The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.
We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.
The data validation involves the primary research from the industry experts belonging to:
- Leading Companies
- Suppliers & Distributors
- Manufacturers
- Consumers
- Industry/Strategic Consultants
Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.
For more details about research methodology, kindly write to us at info@strategymrc.com
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