Cryo Electron Microscopy Market
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PUBLISHED: 2022 ID: SMRC19251
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Cryo-Electron Microscopy Market Forecasts to 2028 – Global Analysis By Type (120kV Cryo-EM, 200kV Cryo-EM, 300kV Cryo-EM), Component (Software, Hardware), Method, Application, and By Geography

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4.6 (68 reviews)
Published: 2022 ID: SMRC19251

This report covers the impact of COVID-19 on this global market
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According to Stratistics MRC, the Global Cryo-Electron Microscopy Market is accounted for $725.43 million in 2021 and is expected to reach $1,525.20 million by 2028 growing at a CAGR of 11.2% during the forecast period. Cryo-electron microscopy is a procedure for imaging frozen-hydrated samples at cryogenic temperatures through electron microscopy. Specimens persevere in their natural state without the need for colors or fixatives, letting the study of adequate viruses, cellular structures and protein multifarious at molecular resolution. Cryo electron microscope is different from using normal microscope. It involves freezing the biological sample in order to view the sample with the least possible distortion and the fewest possible artefacts. Biologists use cryo-electron microscopy to capture pictures of biological samples that have been frozen in their natural states. Cryo electron microscope is faster and effective as compared to other structural biology tools.

Market Dynamics:

Driver:

Rapid technological advancements


New technological advancements is one of the trend in global cryo electron microscope market. The rapid technological advancements and improvement of capabilities such as faster processing and efficient sample preparation techniques is amongst the important factors intensifying the growth and demand of cryo-electron microscopy market. In addition, the increasing focus on nanotechnology and regenerative medicine is also contributing to the growth in the global market over the forecast period. Additionally, the integration of display modalities with these advancements to enhance 3-D images and high definition will fuel the demand of cryo-electron microscopy in various applications, which is likely to drive the cryo-electron microscopy market globally.

Restraint:

High cost of cryo electron microscope


Cryo-EM microscopes are very expensive instruments. The cryo electron microscopy technique is costly, and it takes time to generate the sample also fully hydrated specimen is electron-beam sensitive, which can hamper the growth of Cryo-electron microscopy in coming years. Configurations, customizations, sample accommodation, components, and achieved resolution are the ultimate drivers in the cost of the cryo-electron microscope. However, there are other notable costs that are often overlooked during the buying process. Training, setup and deployment, as well as logistical costs can all contribute to the total cost of ownership of a cryo-electron microscope.

Opportunity:

Favourable funding scenario for R&D


The favourable funding scenario for R&D in microscopy as well as increase in healthcare expenditure and rise in venture capital investments are also enhancing the growth of the market. The rapid increase in viruses and chronic diseases has led to high investment in R&D also the manufacturers are investing heavily to expand and introduce technological advance cryo electron microscope which will further accelerate the expansion of the cryo-electron microscopy market and are also are offering significant growth opportunities for the market in the forecast period. Key players are highly present in North America and Europe owing to the availability of adequate R&D facility.

Threat:

Dearth of skilled professionals


Аlthоugh Сrуо-ЕМ оffеrs hіgh оvеrаll mаgnіfісаtіоn, оnе оf thе mајоr dіѕаdvаntаgеѕ оf Сrуо-еlесtrоn mісrоѕсоре іѕ іt рrоvіdеѕ а vеrу lоw ѕіgnаl tо nоіѕе rаtіо. Fоr bіоlоgісаl mасrоmоlесulеѕ, thе сrіtісаl buіldіng blосkѕ іnсludе саrbоn, hуdrоgеn, охуgеn, аnd nіtrоgеn. Gіvеn thаt еlесtrоn аbѕоrрtіоn оf thеѕе mоlесulеѕ іѕ vеrу lоw, thеn thеrе іѕ lіttlе соntrаѕt оf thе rеѕultіng іmаgеѕ thаt mаkе іt сhаllеngіng tо dеtесt fеаturеѕ оf а gіvеn ѕаmрlе whеn vіеwіng а fеw ѕаmрlеѕ.

The nanotechnology segment is expected to be the largest during the forecast period

The nanotechnology segment is estimated to have a lucrative growth. The nanotechnology segment is expected to expand in the forecast period as compared to the other segments. Nanotechnology is attributed to multiple applications in various fields such as medicine, space program, fabric development, food, fuel cell, solar cell and water purification. There are various development activities and research on nanotechnology and this is considered as one of the driving factors for the growth of this segment.

The cryo-electron tomography segment is expected to have the highest CAGR during the forecast period

The cryo-electron tomography segment is anticipated to witness the fastest CAGR growth during the forecast period.  The cryo-electron tomography segment is likely to register the highest CAGR in the future, owing to its high-quality resolution, which has resulted in easy identification of specimens on deeper levels. Additionally, cryo-electron tomography increases cryo-electron microscopy’s applicability in chemistry to study the structures of compounds, as it allows imaging at a molecular level, and in biology, as these are used to understand viruses and bacteria.

Region with highest share:

North America is projected to hold the largest market share during the forecast period owing to rapidly increasing adoption of advanced technology and higher health coverage within the region. Cryo electron microscope market has various applications in fields such as medicine, space program, fabric development, food, fuel cell, solar cell and water purification which will boost the North American cryo electron microscope market. Government and multiple technology firms are focusing on developing nanotechnology due to its rise in multiple applications and are investing in cryo electron microscope technology. Cryo electron microscope market in the region is expanding due to increase in number of well-equipped diagnostic centers and ongoing clinical trials.

Region with highest CAGR:

Asia Pacific is projected to have the highest CAGR over the forecast period owing to the rapid technological advancements, increase in healthcare expenditure and rise in venture capital investments within this particular region. Global companies are interested to meet the health requirements in countries such as India, China and Japan. There has been exponential rise in investments in multiple industries such as pharmaceuticals and consumer electronics and this will contribute to the cryo electron microscope market in this region and flourishing medical tourism and development in the health care infrastructure will support the market in future and is expected to expand in the forecast period.

Key players in the market

Some of the key players profiled in the Cryo-Electron Microscopy Market include Amgen, Cray Inc, Creative Bio Structure, Delong, Frealign, Hitachi, JEOL, Nvidia Corporation, Relion, Sapphire, Sparx, Structura Biotechnology Inc, Thermo Fisher Scientific, Xmipp, and Zeiss.

Key Developments:

In October 2021, Amgen and USC are teaming up to provide researchers with access to two leading-edge Thermo Scientific cryo-transmission electron microscopes (cryo-TEMs): the Thermo Scientific Krios and Glacios Cryo-TEMs.

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Types Covered:
• 120kV Cryo-EM
• 200kV Cryo-EM
• 300kV Cryo-EM
 
Products Covered:
• Semi-Automatic Cryo-Electron Microscope
• Fully Automatic Cryo-Electron Microscope
 
Components Covered:
• Software
• Hardware
 
Methods Covered:
• Cryo-electron Tomography
• Electron Crystallography
• Single Particle Analysis (SPA)
 
Applications Covered:
• Semiconductors
• Material Sciences
• Lifesciences
• Nanotechnology
• Pharma and Biotech
• Biological Science
• Academic and Research Institute
• Contract Research Organization
• Medical
• Enterprise
• Other Applications

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan       
o China       
o India       
o Australia 
o New Zealand
o South Korea
o Rest of Asia Pacific   
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary        
          
2 Preface        
 
 2.1 Abstract        
 2.2 Stake Holders       
 2.3 Research Scope       
 2.4 Research Methodology      
  2.4.1 Data Mining      
  2.4.2 Data Analysis      
  2.4.3 Data Validation      
  2.4.4 Research Approach      
 2.5 Research Sources       
  2.5.1 Primary Research Sources     
  2.5.2 Secondary Research Sources     
  2.5.3 Assumptions      
          
3 Market Trend Analysis       
 3.1 Introduction       
 3.2 Drivers        
 3.3 Restraints       
 3.4 Opportunities       
 3.5 Threats        
 3.6 Product Analysis       
 3.7 Application Analysis      
 3.8 Emerging Markets       
 3.9 Impact of Covid-19       
          
4 Porters Five Force Analysis       
 4.1 Bargaining power of suppliers      
 4.2 Bargaining power of buyers      
 4.3 Threat of substitutes      
 4.4 Threat of new entrants      
 4.5 Competitive rivalry       
          
5 Global Cryo-Electron Microscopy Market, By Type     
 5.1 Introduction       
 5.2 120kV Cryo-EM       
 5.3 200kV Cryo-EM       
 5.4 300kV Cryo-EM       
          
6 Global Cryo-Electron Microscopy Market, By Product    
 6.1 Introduction       
 6.2 Semi-Automatic Cryo-Electron Microscope    
 6.3 Fully Automatic Cryo-Electron Microscope    
          
7 Global Cryo-Electron Microscopy Market, By Component    
 7.1 Introduction       
 7.2 Software        
 7.3 Hardware       
          
8 Global Cryo-Electron Microscopy Market, By Method    
 8.1 Introduction       
 8.2 Cryo-electron Tomography      
 8.3 Electron Crystallography      
 8.4 Single Particle Analysis (SPA)      
          
9 Global Cryo-Electron Microscopy Market, By Application    
 9.1 Introduction       
 9.2 Semiconductors        
 9.3 Material Sciences       
 9.4 Lifesciences       
 9.5 Nanotechnology       
 9.6 Pharma and Biotech       
 9.7 Biological Science       
 9.8 Academic and Research Institute     
 9.9 Contract Research Organization     
 9.10 Medical         
 9.11 Enterprise       
 9.12 Other Applications       
  9.12.1 Disease Diagnosis      
  9.12.2 Toxicology      
  9.12.3 Pathology      
  9.12.4 Clinical Trials      
          
10 Global Cryo-Electron Microscopy Market, By Geography    

 10.1 Introduction       
 10.2 North America       
  10.2.1 US       
  10.2.2 Canada       
  10.2.3 Mexico       
 10.3 Europe        
  10.3.1 Germany       
  10.3.2 UK       
  10.3.3 Italy       
  10.3.4 France       
  10.3.5 Spain        
  10.3.6 Rest of Europe      
 10.4 Asia Pacific       
  10.4.1 Japan       
  10.4.2 China       
  10.4.3 India       
  10.4.4 Australia       
  10.4.5 New Zealand      
  10.4.6 South Korea      
  10.4.7 Rest of Asia Pacific      
 10.5 South America       
  10.5.1 Argentina      
  10.5.2 Brazil       
  10.5.3 Chile       
  10.5.4 Rest of South America     
 10.6 Middle East & Africa      
  10.6.1 Saudi Arabia      
  10.6.2 UAE       
  10.6.3 Qatar       
  10.6.4 South Africa      
  10.6.5 Rest of Middle East & Africa     
          
11 Key Developments        
 11.1 Agreements, Partnerships, Collaborations and Joint Ventures   
 11.2 Acquisitions & Mergers      
 11.3 New Product Launch      
 11.4 Expansions        
 11.5 Other Key Strategies      
          
12 Company Profiling        
 12.1 Amgen        
 12.2 Cray Inc        
 12.3 Creative Bio Structure      
 12.4 Delong        
 12.5 Frealign        
 12.6 Hitachi        
 12.7 JEOL        
 12.8 Nvidia Corporation       
 12.9 Relion        
 12.10 Sapphire        
 12.11 Sparx        
 12.12 Structura Biotechnology Inc      
 12.13 Thermo Fisher Scientific      
 12.14 Xmipp        
 12.15 Zeiss        


List of Tables         
1 Global Cryo-Electron Microscopy Market Outlook, By Region (2020-2028) ($MN)  
2 Global Cryo-Electron Microscopy Market Outlook, By Type (2020-2028) ($MN)  
3 Global Cryo-Electron Microscopy Market Outlook, By 120kV Cryo-EM (2020-2028) ($MN) 
4 Global Cryo-Electron Microscopy Market Outlook, By 200kV Cryo-EM (2020-2028) ($MN) 
5 Global Cryo-Electron Microscopy Market Outlook, By 300kV Cryo-EM (2020-2028) ($MN) 
6 Global Cryo-Electron Microscopy Market Outlook, By Product (2020-2028) ($MN)  
7 Global Cryo-Electron Microscopy Market Outlook, By Semi-Automatic Cryo-Electron Microscope (2020-2028) ($MN)
8 Global Cryo-Electron Microscopy Market Outlook, By Fully Automatic Cryo-Electron Microscope (2020-2028) ($MN)
9 Global Cryo-Electron Microscopy Market Outlook, By Component (2020-2028) ($MN) 
10 Global Cryo-Electron Microscopy Market Outlook, By Software (2020-2028) ($MN)  
11 Global Cryo-Electron Microscopy Market Outlook, By Hardware (2020-2028) ($MN)  
12 Global Cryo-Electron Microscopy Market Outlook, By Method (2020-2028) ($MN)  
13 Global Cryo-Electron Microscopy Market Outlook, By Cryo-electron Tomography (2020-2028) ($MN)
14 Global Cryo-Electron Microscopy Market Outlook, By Electron Crystallography (2020-2028) ($MN)
15 Global Cryo-Electron Microscopy Market Outlook, By Single Particle Analysis (SPA) (2020-2028) ($MN)
16 Global Cryo-Electron Microscopy Market Outlook, By Application (2020-2028) ($MN) 
17 Global Cryo-Electron Microscopy Market Outlook, By Semiconductors (2020-2028) ($MN) 
18 Global Cryo-Electron Microscopy Market Outlook, By Material Sciences (2020-2028) ($MN) 
19 Global Cryo-Electron Microscopy Market Outlook, By Lifesciences (2020-2028) ($MN) 
20 Global Cryo-Electron Microscopy Market Outlook, By Nanotechnology (2020-2028) ($MN) 
21 Global Cryo-Electron Microscopy Market Outlook, By Pharma and Biotech (2020-2028) ($MN) 
22 Global Cryo-Electron Microscopy Market Outlook, By Biological Science (2020-2028) ($MN) 
23 Global Cryo-Electron Microscopy Market Outlook, By Academic and Research Institute (2020-2028) ($MN)
24 Global Cryo-Electron Microscopy Market Outlook, By Contract Research Organization (2020-2028) ($MN)
25 Global Cryo-Electron Microscopy Market Outlook, By Medical (2020-2028) ($MN)  
26 Global Cryo-Electron Microscopy Market Outlook, By Enterprise (2020-2028) ($MN)  
27 Global Cryo-Electron Microscopy Market Outlook, By Other Applications (2020-2028) ($MN) 
28 Global Cryo-Electron Microscopy Market Outlook, By Disease Diagnosis (2020-2028) ($MN) 
29 Global Cryo-Electron Microscopy Market Outlook, By Toxicology (2020-2028) ($MN)  
30 Global Cryo-Electron Microscopy Market Outlook, By Pathology (2020-2028) ($MN)  
31 Global Cryo-Electron Microscopy Market Outlook, By Clinical Trials (2020-2028) ($MN) 
           
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

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