Gastroesophageal Reflux Disease Market
PUBLISHED: 2023 ID: SMRC24203
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Gastroesophageal Reflux Disease Market

Gastroesophageal Reflux Disease Market Forecasts to 2030 - Global Analysis By Product (Tablet, Capsule, Suspension, Solution and Other Products), Drug Type (Antacids, Proton Pump Inhibitors, H2 Receptor Blocker, Pro Kinetic Agents, Dopamine Receptor Antagonist, EndoCinch, Stretta, EsophyX, Transoral Incisionless, Fundoplication and Other Drug Types), Diagnosis (Upper Endoscopy, Ambulatory Acid (pH) Probe Test, Esophageal Manometry and Other Diagnosis), Route of Administration, Distribution Channel, End User and By Geography

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4.0 (67 reviews)
Published: 2023 ID: SMRC24203

This report covers the impact of COVID-19 on this global market
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Years Covered

2021-2030

Estimated Year Value (2023)

US $5.37 BN

Projected Year Value (2030)

US $6.93 BN

CAGR (2023 - 2030)

3.7%

Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

North America

Highest Growing Market

Asia Pacific


According to Stratistics MRC, the Global Gastroesophageal Reflux Disease Market is accounted for $5.37 billion in 2023 and is expected to reach $6.93 billion by 2030 growing at a CAGR of 3.7% during the forecast period. Heartburn is a burning sensation that is brought on by a condition called gastroesophageal reflux disease (GERD). Moreover, reflux, a backward movement that produces a burning sensation in the lower part of the esophagus, is what happens when the stomach's hydrochloric acid-containing contents travel upward again.

According to an article updated by the National Center for Biotechnology Information (NCBI) in May 2022, tobacco smoking is considered an etiological factor of reflux esophagitis or acid reflux and it is considered a major risk factor for acid reflux over the age of 50. 

Market Dynamics: 

Driver: 

New approaches to drug development

The pharmaceutical industry's dedication to GERD research and development has resulted in the development of increasingly safe and effective drugs for the condition's management. Additionally, innovations include not only the creation of new drug formulations but also personalized medicine strategies that customize treatments for specific patients based on lifestyle and genetic factors. By addressing GERD-related complications like Barrett's esophagus, esophageal cancer, and respiratory disorders, these innovations offer a more all-encompassing approach to treatment and prevention.

Restraint:

Overuse and adverse reactions to medication

Proton pump inhibitors (PPIs), one type of medication used to treat GERD should not be used for an extended period of time due to the risk of side effects. PPIs are useful, but they raise questions about kidney function, bone health, and nutrient malabsorption. Furthermore, it can be difficult for patients and healthcare professionals to manage these side effects and strike a balance between short-term symptom relief and long-term health.

Opportunity:

Technologies for diagnostic instruments

An important opportunity for the early and precise diagnosis of GERD is provided by continuous improvements in diagnostic tools, such as high-resolution esophageal manometry, ambulatory pH monitoring, and sophisticated endoscopy methods like confocal laser endomicroscopy. These instruments facilitate the evaluation of the degree of esophageal injury, the detection of complications such as Barrett's esophagus, and the choice of the best course of action for selected patients. Moreover, patients can receive more effective and individualized treatments aimed at symptom relief and long-term problem prevention with an earlier and more accurate diagnosis.

Threat:

Tolerance and resistance to medication

Proton pump inhibitors (PPIs) in particular should not be used for extended periods of time, as some patients may develop drug resistance and tolerance. It is possible that these drugs will lose their effectiveness with time and that higher doses or other medications will be necessary. Additionally, patients who seek stronger medications or more therapies to manage their symptoms may become resistant to their prescribed medications, which can make treatment decisions more difficult and raise medical expenses.

Covid-19 Impact: 

Gastroesophageal reflux disease (GERD) and the global healthcare market have both been significantly impacted by the COVID-19 pandemic. Significant changes in patient behavior and healthcare delivery were also brought about by the pandemic, even though it first caused disruptions to healthcare services and supply chains, including the manufacture and distribution of GERD medications and medical devices. Furthermore, lockdowns and other social distancing measures led to a spike in the use of telemedicine and remote monitoring for GERD patients, which allowed for continued care while lowering the risk of contracting the virus.

The Capsule segment is expected to be the largest during the forecast period

It is projected that the capsule segment will command the largest market share for gastroesophageal reflux disease. Because of their adaptability, simplicity in production, and patient-friendly qualities, capsules are widely used. They offer a practical and efficient means of delivering a variety of pharmaceutical formulations, such as liquid, semi-solid, or solid substances. Patients of all ages prefer capsules because they provide accurate dosing and ease of swallowing, making them a popular choice for both prescription and over-the-counter medications. Furthermore, capsules can be used for a wide range of therapeutic applications, including the formulation of specialty drugs, vitamins, herbal supplements, and antibiotics.

The Homecare segment is expected to have the highest CAGR during the forecast period

Over the course of the projection period, the homecare segment has shown the highest CAGR. The need for homecare services has increased significantly as a result of a number of factors, such as the aging population, the desire for individualized care in comfortable settings, and developments in telehealth and medical technology. Moreover, homecare services are appealing for patients who need ongoing care, monitoring, or rehabilitation while remaining in their own homes because they cover a wide range of medical and non-medical assistance. Depending on the patient's needs, these services can include physical therapy, medication management, nursing care, and even complex medical procedures.

Region with largest share:

The region of North America is projected to possess the largest market share. The region is well-known for a number of reasons, including a strong pharmaceutical and medical device industry, a large healthcare infrastructure, and high healthcare spending. Particularly in terms of drug development and innovation, the pharmaceutical industry in the United States is substantial. Another factor in North America's dominance is the abundance of internationally recognized research centers and healthcare facilities. Additionally, the North American healthcare market is still changing, with an increasing emphasis on value-based care, innovative therapies, and medical technology.

Region with highest CAGR:

The market's highest CAGR is being experienced by the Asia-Pacific region. Numerous factors, such as the fast-growing population, growing urbanization, increased awareness of healthcare, and significant economic development in nations like China and India, can be credited for this robust growth. These countries are seeing large investments in pharmaceuticals, medical technology, and healthcare infrastructure. Furthermore, the Asia-Pacific area is becoming known as a center for clinical trials and research, drawing pharmaceutical and medical device manufacturers from throughout the world.

Key players in the market

Some of the key players in Gastroesophageal Reflux Disease market include Medtronic Plc, Takeda Pharmaceutical Company Limited., Johnson & Johnson Services Inc., GlaxoSmithKline PLC, Olympus Corporation, TWi Pharmaceuticals, Inc, Ironwood Pharmaceuticals, Inc., SRS Life Sciences, Reckitt Benckiser Group PLC, Zydus Group, AstraZeneca PLC, Camber Pharmaceuticals, Inc., Pfizer Inc., Teva Pharmaceuticals Industries Limited., Aurobindo Pharma, Sebela Pharmaceuticals, Phathom Pharmaceuticals, Inc. and SFJ Pharmaceuticals.

Key Developments:

In May 2023, Medtronic plc, a global leader in healthcare technology, today announced it has entered into a set of definitive agreements to acquire EOFlow Co. Ltd., manufacturer of the EOPatch® device a tubeless, wearable and fully disposable insulin delivery device. The addition of EOFlow, together with Medtronic's Meal Detection Technology™ algorithm and next-generation continuous glucose monitor, is expected to expand the company's ability to address the needs of more individuals with diabetes, no matter where they are in their treatment journey or preference for how they want their insulin delivered.

In May 2023, Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has entered into a worldwide collaboration and license agreement with Cellular Biomedicine Group Inc. (CBMG) to develop, manufacture and commercialize next-generation chimeric antigen receptor (CAR) T-cell therapies for the treatment of B-cell malignancies. 

In January 2023, Takeda has signed an exclusive licence agreement with HUTCHMED (China) and its subsidiary HUTCHMED to develop and market the latter’s fruquintinib. Under the deal terms, the company will have an exclusive global licence for the development and commercialisation of fruquintinib for all indications and territories outside of mainland China, Macau, and Hong Kong.

Products Covered:
• Tablet
• Capsule
• Suspension
• Solution
• Other Products 
 
Drug Types Covered:
• Antacids
• Proton Pump Inhibitors
• H2 Receptor Blocker
• Pro Kinetic Agents
• Dopamine Receptor Antagonist
• EndoCinch
• Stretta
• EsophyX
• Transoral Incisionless
• Fundoplication
• Other Drug Types 

Diagnosis Covered:
• Upper Endoscopy
• Ambulatory Acid (pH) Probe Test
• Esophageal Manometry
• Other Diagnosis 

Route of Administrations Covered:
• Oral
• Parental 

Distribution Channels Covered:
• Hospital Pharmacy
• Online Pharmacy
• Retail Pharmacy 

End Users Covered:
• Hospital
• Homecare
• Specialty Clinics
• Other End Users 

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan        
o China        
o India        
o Australia  
o New Zealand
o South Korea
o Rest of Asia Pacific    
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa 
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2021, 2022, 2023, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings: 
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary             
              
2 Preface             
 2.1 Abstract            
 2.2 Stake Holders            
 2.3 Research Scope            
 2.4 Research Methodology            
  2.4.1 Data Mining           
  2.4.2 Data Analysis           
  2.4.3 Data Validation           
  2.4.4 Research Approach           
 2.5 Research Sources            
  2.5.1 Primary Research Sources           
  2.5.2 Secondary Research Sources           
  2.5.3 Assumptions           
              
3 Market Trend Analysis             
 3.1 Introduction            
 3.2 Drivers            
 3.3 Restraints            
 3.4 Opportunities            
 3.5 Threats            
 3.6 Product Analysis            
 3.7 End User Analysis            
 3.8 Emerging Markets            
 3.9 Impact of Covid-19            
              
4 Porters Five Force Analysis             
 4.1 Bargaining power of suppliers            
 4.2 Bargaining power of buyers            
 4.3 Threat of substitutes            
 4.4 Threat of new entrants            
 4.5 Competitive rivalry            
              
5 Global Gastroesophageal Reflux Disease Market, By Product             
 5.1 Introduction            
 5.2 Tablet            
 5.3 Capsule            
 5.4 Suspension            
 5.5 Solution            
 5.6 Other Products            
              
6 Global Gastroesophageal Reflux Disease Market, By Drug Type             
 6.1 Introduction            
 6.2 Antacids            
 6.3 Proton Pump Inhibitors            
 6.4 H2 Receptor Blocker            
 6.5 Pro Kinetic Agents            
 6.6 Dopamine Receptor Antagonist            
 6.7 EndoCinch            
 6.8 Stretta            
 6.9 EsophyX            
 6.10 Transoral Incisionless            
 6.11 Fundoplication            
 6.12 Other Drug Types            
              
7 Global Gastroesophageal Reflux Disease Market, By Diagnosis             
 7.1 Introduction            
 7.2 Upper Endoscopy            
 7.3 Ambulatory Acid (pH) Probe Test            
 7.4 Esophageal Manometry            
 7.5 Other Diagnosis            
              
8 Global Gastroesophageal Reflux Disease Market, By Route of Administration             
 8.1 Introduction            
 8.2 Oral            
 8.3 Parental            
              
9 Global Gastroesophageal Reflux Disease Market, By Distribution Channel             
 9.1 Introduction            
 9.2 Hospital Pharmacy            
 9.3 Online Pharmacy            
 9.4 Retail Pharmacy            
              
10 Global Gastroesophageal Reflux Disease Market, By End User             
 10.1 Introduction            
 10.2 Hospital            
 10.3 Homecare            
 10.4 Specialty Clinics            
 10.5 Other End Users            
              
11 Global Gastroesophageal Reflux Disease Market, By Geography             
 11.1 Introduction            
 11.2 North America            
  11.2.1 US           
  11.2.2 Canada           
  11.2.3 Mexico           
 11.3 Europe            
  11.3.1 Germany           
  11.3.2 UK           
  11.3.3 Italy           
  11.3.4 France           
  11.3.5 Spain           
  11.3.6 Rest of Europe           
 11.4 Asia Pacific            
  11.4.1 Japan           
  11.4.2 China           
  11.4.3 India           
  11.4.4 Australia           
  11.4.5 New Zealand           
  11.4.6 South Korea           
  11.4.7 Rest of Asia Pacific           
 11.5 South America            
  11.5.1 Argentina           
  11.5.2 Brazil           
  11.5.3 Chile           
  11.5.4 Rest of South America           
 11.6 Middle East & Africa            
  11.6.1 Saudi Arabia           
  11.6.2 UAE           
  11.6.3 Qatar           
  11.6.4 South Africa           
  11.6.5 Rest of Middle East & Africa           
              
12 Key Developments             
 12.1 Agreements, Partnerships, Collaborations and Joint Ventures            
 12.2 Acquisitions & Mergers            
 12.3 New Product Launch            
 12.4 Expansions            
 12.5 Other Key Strategies            
              
13 Company Profiling             
 13.1 Medtronic Plc            
 13.2 Takeda Pharmaceutical Company Limited.            
 13.3 Johnson & Johnson Services Inc.            
 13.4 GlaxoSmithKline PLC            
 13.5 Olympus Corporation            
 13.6 TWi Pharmaceuticals, Inc.            
 13.7 Ironwood Pharmaceuticals, Inc.            
 13.8 SRS Life Sciences            
 13.9 Reckitt Benckiser Group PLC            
 13.10 Zydus Group            
 13.11 AstraZeneca PLC            
 13.12 Camber Pharmaceuticals, Inc.            
 13.13 Pfizer Inc.            
 13.14 Teva Pharmaceuticals Industries Limited.            
 13.15 Aurobindo Pharma            
 13.16 Sebela Pharmaceuticals            
 13.17 Phathom Pharmaceuticals, Inc.            
 13.18 SFJ Pharmaceuticals            
              
List of Tables              
1 Global Gastroesophageal Reflux Disease Market Outlook, By Region (2021-2030) ($MN)             
2 Global Gastroesophageal Reflux Disease Market Outlook, By Product (2021-2030) ($MN)             
3 Global Gastroesophageal Reflux Disease Market Outlook, By Tablet (2021-2030) ($MN)             
4 Global Gastroesophageal Reflux Disease Market Outlook, By Capsule (2021-2030) ($MN)             
5 Global Gastroesophageal Reflux Disease Market Outlook, By Suspension (2021-2030) ($MN)             
6 Global Gastroesophageal Reflux Disease Market Outlook, By Solution (2021-2030) ($MN)             
7 Global Gastroesophageal Reflux Disease Market Outlook, By Other Products (2021-2030) ($MN)             
8 Global Gastroesophageal Reflux Disease Market Outlook, By Drug Type (2021-2030) ($MN)             
9 Global Gastroesophageal Reflux Disease Market Outlook, By Antacids (2021-2030) ($MN)             
10 Global Gastroesophageal Reflux Disease Market Outlook, By Proton Pump Inhibitors (2021-2030) ($MN)             
11 Global Gastroesophageal Reflux Disease Market Outlook, By H2 Receptor Blocker (2021-2030) ($MN)             
12 Global Gastroesophageal Reflux Disease Market Outlook, By Pro Kinetic Agents (2021-2030) ($MN)             
13 Global Gastroesophageal Reflux Disease Market Outlook, By Dopamine Receptor Antagonist (2021-2030) ($MN)             
14 Global Gastroesophageal Reflux Disease Market Outlook, By EndoCinch (2021-2030) ($MN)             
15 Global Gastroesophageal Reflux Disease Market Outlook, By Stretta (2021-2030) ($MN)             
16 Global Gastroesophageal Reflux Disease Market Outlook, By EsophyX (2021-2030) ($MN)             
17 Global Gastroesophageal Reflux Disease Market Outlook, By Transoral Incisionless (2021-2030) ($MN)             
18 Global Gastroesophageal Reflux Disease Market Outlook, By Fundoplication (2021-2030) ($MN)             
19 Global Gastroesophageal Reflux Disease Market Outlook, By Other Drug Types (2021-2030) ($MN)             
20 Global Gastroesophageal Reflux Disease Market Outlook, By Diagnosis (2021-2030) ($MN)             
21 Global Gastroesophageal Reflux Disease Market Outlook, By Upper Endoscopy (2021-2030) ($MN)             
22 Global Gastroesophageal Reflux Disease Market Outlook, By Ambulatory Acid (pH) Probe Test (2021-2030) ($MN)             
23 Global Gastroesophageal Reflux Disease Market Outlook, By Esophageal Manometry (2021-2030) ($MN)             
24 Global Gastroesophageal Reflux Disease Market Outlook, By Other Diagnosis (2021-2030) ($MN)             
25 Global Gastroesophageal Reflux Disease Market Outlook, By Route of Administration (2021-2030) ($MN)             
26 Global Gastroesophageal Reflux Disease Market Outlook, By Oral (2021-2030) ($MN)             
27 Global Gastroesophageal Reflux Disease Market Outlook, By Parental (2021-2030) ($MN)             
28 Global Gastroesophageal Reflux Disease Market Outlook, By Distribution Channel (2021-2030) ($MN)             
29 Global Gastroesophageal Reflux Disease Market Outlook, By Hospital Pharmacy (2021-2030) ($MN)             
30 Global Gastroesophageal Reflux Disease Market Outlook, By Online Pharmacy (2021-2030) ($MN)             
31 Global Gastroesophageal Reflux Disease Market Outlook, By Retail Pharmacy (2021-2030) ($MN)             
32 Global Gastroesophageal Reflux Disease Market Outlook, By End User (2021-2030) ($MN)             
33 Global Gastroesophageal Reflux Disease Market Outlook, By Hospital (2021-2030) ($MN)             
34 Global Gastroesophageal Reflux Disease Market Outlook, By Homecare (2021-2030) ($MN)             
35 Global Gastroesophageal Reflux Disease Market Outlook, By Specialty Clinics (2021-2030) ($MN)             
36 Global Gastroesophageal Reflux Disease Market Outlook, By Other End Users (2021-2030) ($MN)             
              
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.               

List of Figures

RESEARCH METHODOLOGY


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.


Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.


For more details about research methodology, kindly write to us at info@strategymrc.com

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