Immunohistochemistry Market

Immunohistochemistry Market

Immunohistochemistry Market Forecasts to 2028 - Global Analysis By Product (Kits, Antibody, Equipment and Reagents), Distribution channel (Research Applications, Diagnosis and Forensic) and End User and By Geography

4.4 (71 reviews)
4.4 (71 reviews)
Published: 2023 ID: SMRC23106

This report covers the impact of COVID-19 on this global market

Years Covered


Estimated Year Value (2022)

US $2.60 BN

Projected Year Value (2028)

US $4.24 BN

CAGR (2022 - 2028)


Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

North America

Highest Growing Market

Asia Pacific

According to Stratistics MRC, the Global Immunohistochemistry Market is accounted for $2.60 billion in 2022 and is expected to reach $4.24 billion by 2028 growing at a CAGR of 8.5% during the forecast period. Immunohistochemistry is critical for biomarker development. Immunohistochemistry is a microscopy method used to identify antigens and macromolecular cellular components. It requires visualising the presence and localisation of the target protein in various cell types, biological cycles, and even subcellular localization within complex tissues. Recent advancements in IHC include the sensitive detection of numerous proteins in a single sample and the ease of detecting protein-protein interactions. This technique can be used to test drugs and diagnose a variety of ailments.

According to the World Health Organization (WHO) Fact sheet, February 2022, cancer is a leading cause of death worldwide, and accounted for around 10 million deaths in 2020, or nearly one in six deaths.

Market Dynamics:


Rising geriatric population

The prevalence of age-related disorders is expected to climb dramatically as the global geriatric population grows rapidly. Geriatric populations are large and growing in other industrialised economies around the world. The chance of developing infections increases proportionally with age. As a result, it is expected that the prevalence of various diseases would increase internationally as the elderly population grows. This is regarded as an important driving force in the Immunohistochemistry (IHC) market for diagnostic applications.


High degree of consolidation

Antibody patent expiration is a major issue for the global market. Some Merck (Germany) and F. Hoffmann-La Roche AG (Switzerland) primary antibodies are about to lose patent protection. Furthermore, market participants must deal with challenges such as growing price pressure from governments around the world and reduced R&D output. To overcome these barriers, prominent market leaders are acquiring smaller and mid-sized firms with unique patented products. This provides a huge financial and distribution platform for these products to enter new global markets.


New product launches

Key market leaders focusing on technological developments in response to current needs would boost industry development. The market is expected to grow due to the launch of new immunohistochemistry products to address the previously mentioned issues. The top companies are producing cutting-edge goods that are expected to drive market expansion. The introduction of these clinical diagnostic markers might help to advance early-stage drug development for cancer treatment in immuno-oncology. The market would grow quicker throughout the predicted period due to increased R&D.


Dearth of skilled professionals

As the prevalence of cancer has increased, so has the demand for pathology services for clinical applications. The majority of examinations conducted on cancer patients are performed using histopathology technologies. However, there is a shortage of trained personnel in these laboratories. A considerable number of histopathologists have reached retirement age, and only a limited number of new histopathologists are being trained. On the other hand, laboratories are under pressure to process an increasing quantity of specimens with restricted personnel.

Covid-19 Impact

The COVID-19 outbreak has had a favourable influence on the immunohistochemistry market, owing to an increase in the prevalence of COVID-19 infections worldwide and an increase in the usage of immunohistochemistry techniques for the detection of COVI-19 infections. For example, immunohistochemistry (IHC) and in situ hybridization (ISH) techniques are employed to detect SARS-CoV-2, according to a July 2020 paper published in Laboratory Investigation. All samples were IHC and ISH positive, whereas all specimens from non-COVID-19 patients were IHC and ISH negative. As a result, the impact of the coronavirus (COVID-19) pandemic has remained positive for the global immunohistochemistry (IHC) market.

The antibody segment is expected to be the largest during the forecast period

The antibody segment is estimated to have a lucrative growth, due to the vital usage of antibodies in disease diagnosis and drug testing. Monoclonal antibodies and antibody-related goods such as Fc-fusion, antibody fragments, and antibody-drug conjugates have surpassed all other product classes in terms of usage rate. The antibodies are used in a variety of applications including pathology, neuropathology, and hematopathology. The increasing usage of research antibodies for drug discovery is another major factor driving the development of the antibodies market.

The diagnosis segment is expected to have the highest CAGR during the forecast period

The diagnosis segment is anticipated to witness the highest CAGR growth during the forecast period. Immunohistochemistry tests can be used to diagnose a variety of chronic disorders, including autoimmune diseases, cancer, infectious diseases, cardiovascular diseases, diabetes mellitus, and nephrological diseases. Furthermore, the growing prevalence of chronic disorders is expected to fuel the diagnostics industry. The majority of infectious diseases and the favourable reimbursement environment for IHC tests are additional factors driving the segment's market share growth.

Region with highest share:

North America is projected to hold the largest market share during the forecast period. The dominance of the North American region can be attributable to the growing use of this immunohistochemistry equipment in diagnostic centres and laboratories. Furthermore, attractive reimbursement regulations in countries like as the United States and Canada encourage the use of automated devices, which helps the growth of the IHC market in the North American region. Additionally, an increase in the number of cancer patients from North American countries is expected to increase the need for these immunohistochemical approaches.

Region with highest CAGR:

Asia Pacific is projected to have the highest CAGR over the forecast period. The rapid increase of the Asia-Pacific immunohistochemistry market can be attributed to the economic prosperity of nations such as India, China, South Korea, and Singapore. Furthermore, a big patient pool in countries such as India and China provides a significant number of clinical subjects for IHC R&D tests, leading in revenue growth. Aside from these, the high prevalence of chronic diseases and the rapid ageing of the population are two additional factors driving the growth of the Asia-Pacific Immunohistochemistry Industry.

Key players in the market

Some of the key players profiled in the Immunohistochemistry Market include Agilent Technologies, Inc., Abcam plc., Bio SB, Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Danaher Corporation, F. Hoffmann-La Roche Ltd., Merck KGaA, Perkinelmer, Inc., F hoffman La Roche, Eagle Biosciences, Inc., CANDOR Bioscience GmbH, Elabscience, Inc., Thermofischer Scientific Inc and Biogenex Laboratories.

Key Developments:

In August 2021, Roche received FDA approval for VENTANA MMR RxDx companion diagnostic test based on immunohistochemistry for solid tumors that are deficient in the MMR pathway. The test identifies patients eligible for GSK’s anti-PD1 immunotherapy, JEMPERLI.

In August 2021, Agilent received a CE-IVD mark in Europe for its PD-L1 IHC 22C3 pharmDx assay for the identification of oesophageal cancer patients for treatment with KEYTRUDA.

Products Covered:
• Kits
• Antibody
• Equipment
• Reagents

Applications Covered:
• Research Applications
• Diagnosis
• Forensic

End Users Covered:
• Research Institutes and Academic Institutes
• Hospital and Diagnostic Labs
• Other End Users

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions

3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19

4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 Global Immunohistochemistry Market, By Product
5.1 Introduction
5.2 Kits
5.2.1 IHC Kits for Human Tissue
5.2.2 IHC Kits for Animal Tissue
5.3 Antibody
5.3.1 Primary Antibodies
5.3.2 Secondary Antibodies
5.4 Equipment
5.4.1 Tissue Processing Systems
5.4.2 Slide Scanners
5.4.3 Slide staining Systems
5.4.4 Other Equipments
5.5 Reagents
5.5.1 Proteolytic Enzymes
5.5.2 Organic Solvents
5.5.3 Chromogenic Substrates
5.5.4 Diluents
5.5.5 Histological Stains
5.5.6 Fixation Reagents
5.5.7 Blocking Sera and Reagents
5.5.8 Other Reagents

6 Global Immunohistochemistry Market, By Application
6.1 Introduction
6.2 Research Applications
6.2.1 Drug Testing
6.2.2 Other Research Applications
6.3 Diagnosis
6.3.1 Autoimmune diseases
6.3.2 Cancer
6.3.3 Infectious diseases
6.3.4 Nephrological diseases
6.3.5 Neurological diseases
6.3.6 Other Diagnosis
6.4 Forensic

7 Global Immunohistochemistry Market, By End User
7.1 Introduction
7.2 Research Institutes and Academic Institutes
7.3 Hospital and Diagnostic Labs
7.4 Other End Users
7.4.1 Pharma & Biopharma Companies
7.4.2 Forensic Laboratories
7.4.3 CROs

8 Global Immunohistochemistry Market, By Geography
8.1 Introduction
8.2 North America
8.2.1 US
8.2.2 Canada
8.2.3 Mexico
8.3 Europe
8.3.1 Germany
8.3.2 UK
8.3.3 Italy
8.3.4 France
8.3.5 Spain
8.3.6 Rest of Europe
8.4 Asia Pacific
8.4.1 Japan
8.4.2 China
8.4.3 India
8.4.4 Australia
8.4.5 New Zealand
8.4.6 South Korea
8.4.7 Rest of Asia Pacific
8.5 South America
8.5.1 Argentina
8.5.2 Brazil
8.5.3 Chile
8.5.4 Rest of South America
8.6 Middle East & Africa
8.6.1 Saudi Arabia
8.6.2 UAE
8.6.3 Qatar
8.6.4 South Africa
8.6.5 Rest of Middle East & Africa

9 Key Developments
9.1 Agreements, Partnerships, Collaborations and Joint Ventures
9.2 Acquisitions & Mergers
9.3 New Product Launch
9.4 Expansions
9.5 Other Key Strategies

10 Company Profiling
10.1 Agilent Technologies, Inc.
10.2 Abcam plc.
10.3 Bio SB
10.4 Bio-Rad Laboratories, Inc.
10.5 Cell Signaling Technology, Inc.
10.6 Danaher Corporation
10.7 F. Hoffmann-La Roche Ltd.
10.8 Merck KGaA
10.9 Perkinelmer, Inc.
10.10 F hoffman La Roche
10.11 Eagle Biosciences, Inc.
10.12 CANDOR Bioscience GmbH
10.13 Elabscience, Inc.
10.14 Thermofischer Scientific Inc
10.15 Biogenex Laboratories

List of Tables
1 Global Immunohistochemistry Market Outlook, By Region (2020-2028) ($MN)
2 Global Immunohistochemistry Market Outlook, By Product (2020-2028) ($MN)
3 Global Immunohistochemistry Market Outlook, By Kits (2020-2028) ($MN)
4 Global Immunohistochemistry Market Outlook, By IHC Kits for Human Tissue (2020-2028) ($MN)
5 Global Immunohistochemistry Market Outlook, By IHC Kits for Animal Tissue (2020-2028) ($MN)
6 Global Immunohistochemistry Market Outlook, By Antibody (2020-2028) ($MN)
7 Global Immunohistochemistry Market Outlook, By Primary Antibodies (2020-2028) ($MN)
8 Global Immunohistochemistry Market Outlook, By Secondary Antibodies (2020-2028) ($MN)
9 Global Immunohistochemistry Market Outlook, By Equipment (2020-2028) ($MN)
10 Global Immunohistochemistry Market Outlook, By Tissue Processing Systems (2020-2028) ($MN)
11 Global Immunohistochemistry Market Outlook, By Slide Scanners (2020-2028) ($MN)
12 Global Immunohistochemistry Market Outlook, By Slide staining Systems (2020-2028) ($MN)
13 Global Immunohistochemistry Market Outlook, By Other Equipments (2020-2028) ($MN)
14 Global Immunohistochemistry Market Outlook, By Reagents (2020-2028) ($MN)
15 Global Immunohistochemistry Market Outlook, By Proteolytic Enzymes (2020-2028) ($MN)
16 Global Immunohistochemistry Market Outlook, By Organic Solvents (2020-2028) ($MN)
17 Global Immunohistochemistry Market Outlook, By Chromogenic Substrates (2020-2028) ($MN)
18 Global Immunohistochemistry Market Outlook, By Diluents (2020-2028) ($MN)
19 Global Immunohistochemistry Market Outlook, By Histological Stains (2020-2028) ($MN)
20 Global Immunohistochemistry Market Outlook, By Fixation Reagents (2020-2028) ($MN)
21 Global Immunohistochemistry Market Outlook, By Blocking Sera and Reagents (2020-2028) ($MN)
22 Global Immunohistochemistry Market Outlook, By Other Reagents (2020-2028) ($MN)
23 Global Immunohistochemistry Market Outlook, By Application (2020-2028) ($MN)
24 Global Immunohistochemistry Market Outlook, By Research Applications (2020-2028) ($MN)
25 Global Immunohistochemistry Market Outlook, By Drug Testing (2020-2028) ($MN)
26 Global Immunohistochemistry Market Outlook, By Other Research Applications (2020-2028) ($MN)
27 Global Immunohistochemistry Market Outlook, By Diagnosis (2020-2028) ($MN)
28 Global Immunohistochemistry Market Outlook, By Autoimmune diseases (2020-2028) ($MN)
29 Global Immunohistochemistry Market Outlook, By Cancer (2020-2028) ($MN)
30 Global Immunohistochemistry Market Outlook, By Infectious diseases (2020-2028) ($MN)
31 Global Immunohistochemistry Market Outlook, By Nephrological diseases (2020-2028) ($MN)
32 Global Immunohistochemistry Market Outlook, By Neurological diseases (2020-2028) ($MN)
33 Global Immunohistochemistry Market Outlook, By Other Diagnosis (2020-2028) ($MN)
34 Global Immunohistochemistry Market Outlook, By Forensic (2020-2028) ($MN)
35 Global Immunohistochemistry Market Outlook, By End User (2020-2028) ($MN)
36 Global Immunohistochemistry Market Outlook, By Research Institutes and Academic Institutes (2020-2028) ($MN)
37 Global Immunohistochemistry Market Outlook, By Hospital and Diagnostic Labs (2020-2028) ($MN)
38 Global Immunohistochemistry Market Outlook, By Other End Users (2020-2028) ($MN)
39 Global Immunohistochemistry Market Outlook, By Pharma & Biopharma Companies (2020-2028) ($MN)
40 Global Immunohistochemistry Market Outlook, By Forensic Laboratories (2020-2028) ($MN)
41 Global Immunohistochemistry Market Outlook, By CROs (2020-2028) ($MN)

Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.

Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.

For more details about research methodology, kindly write to us at

Frequently Asked Questions

In case of any queries regarding this report, you can contact the customer service by filing the “Inquiry Before Buy” form available on the right hand side. You may also contact us through email: or phone: +1-301-202-5929

Yes, the samples are available for all the published reports. You can request them by filling the “Request Sample” option available in this page.

Yes, you can request a sample with your specific requirements. All the customized samples will be provided as per the requirement with the real data masked.

All our reports are available in Digital PDF format. In case if you require them in any other formats, such as PPT, Excel etc you can submit a request through “Inquiry Before Buy” form available on the right hand side. You may also contact us through email: or phone: +1-301-202-5929

We offer a free 15% customization with every purchase. This requirement can be fulfilled for both pre and post sale. You may send your customization requirements through email at or call us on +1-301-202-5929.

We have 3 different licensing options available in electronic format.

  • Single User Licence: Allows one person, typically the buyer, to have access to the ordered product. The ordered product cannot be distributed to anyone else.
  • 2-5 User Licence: Allows the ordered product to be shared among a maximum of 5 people within your organisation.
  • Corporate License: Allows the product to be shared among all employees of your organisation regardless of their geographical location.

All our reports are typically be emailed to you as an attachment.

To order any available report you need to register on our website. The payment can be made either through CCAvenue or PayPal payments gateways which accept all international cards.

We extend our support to 6 months post sale. A post sale customization is also provided to cover your unmet needs in the report.

Request Customization

We provide a free 15% customization on every purchase. This requirement can be fulfilled for both pre and post sale. You may send your customization requirements through email at or call us on +1-301-202-5929.

Note: This customization is absolutely free until it falls under the 15% bracket. If your requirement exceeds this a feasibility check will be performed. Post that, a quote will be provided along with the timelines.


Assured Quality

Assured Quality

Best in class reports with high standard of research integrity

24X7 Research Support

24X7 Research Support

Continuous support to ensure the best customer experience.

Free Customization

Free Customization

Adding more values to your product of interest.

Safe and Secure Access

Safe & Secure Access

Providing a secured environment for all online transactions.

Trusted by 600+ Brands

Trusted by 600+ Brands

Serving the most reputed brands across the world.