Medicinal Chemistry For Drug Discovery Market
PUBLISHED: 2023 ID: SMRC24369
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Medicinal Chemistry For Drug Discovery Market

Medicinal Chemistry For Drug Discovery Market Forecasts to 2030 - Global Analysis By Process (Target Selection, Candidate Validation, Hit-to-Lead Identification, and Lead Optimization), Design (Fragment-Based Variation, Diversity Oriented Synthesis, Structure Based Drug Design, Natural Products, Chemogenomics and Other Designs), Drug Type, Therapeutic Area, End User and By Geography

4.2 (89 reviews)
4.2 (89 reviews)
Published: 2023 ID: SMRC24369

This report covers the impact of COVID-19 on this global market
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Years Covered

2021-2030

Estimated Year Value (2023)

US $92.50 BN

Projected Year Value (2030)

US $224.45 BN

CAGR (2023 - 2030)

13.5%

Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

Asia Pacific

Highest Growing Market

North America


According to Stratistics MRC, the Global Medicinal Chemistry For Drug Discovery Market is accounted for $92.50 billion in 2023 and is expected to reach $224.45 billion by 2030 growing at a CAGR of 13.5% during the forecast period. Medicinal chemistry for drug discovery is a multidisciplinary field that combines principles of chemistry, biology, and pharmacology to design and develop new pharmaceutical compounds. It aims to identify and optimise molecules with therapeutic potential, considering factors such as safety, efficacy, and mechanism of action, ultimately leading to the creation of novel drugs for the treatment of diseases.

According to the World Health Organization, the cardiovascular diseases results in almost 18 million deaths each year and it is the leading cause of death across the globe.

Market Dynamics: 

Driver: 

Expanding healthcare facilities

The expanding and improved accessibility of healthcare infrastructure raises the need for novel pharmaceutical solutions. This expansion includes the establishment of new hospitals, clinics, and research centres, providing a platform for clinical trials and drug testing. Additionally, improved healthcare facilities enhance patient care, leading to greater diagnosis and treatment of various medical conditions. Moreover, expanding facilities attracts investments from both the public and private sectors, supports research, and fosters collaboration between pharmaceutical companies and healthcare institutions, which accelerates the discovery and development of new drugs.

Restraint:

Rising development costs

The process of bringing a new drug from discovery to market approval is capital-intensive, encompassing preclinical studies, extensive clinical trials, and regulatory compliance. These expenses include research, personnel, infrastructure, and compliance with rigorous safety and efficacy standards. The financial burden of these expenses may deter investment in potentially lethal drug candidates and restrict access to advanced therapies, ultimately hindering the field's advancement as well as delaying the release of novel treatments for patients.

Opportunity:

Integration of digital health and AI

AI and digital health technologies enable pharmaceutical researchers to process vast datasets, accelerating the identification of potential drug candidates and predicting their behaviour in biological systems. Machine learning algorithms can analyse molecular structures and identify drug-target interactions, streamlining the lead optimisation process. These technologies also support remote patient monitoring and real-world evidence generation, improving drug safety and efficacy assessments. The synergy between AI and digital health not only expedites drug discovery but also holds the promise of more personalised and effective therapies, attracting substantial investment and innovation in the pharmaceutical industry. Thus, these technologies are propelling market growth.

Threat:

High failure rates

The majority of potential medication combinations do not reach the market because of safety issues, ineffectiveness, or unexpected adverse effects. The drug development process is plagued with uncertainty. Moreover, these failures result in substantial financial losses for pharmaceutical companies and can deter investment in research. The extensive time and resources invested in unsuccessful drugs can hinder innovation and limit the availability of novel therapies, ultimately compromising the industry's ability to address unmet medical needs and improve patient outcomes.

Covid-19 Impact

The COVID-19 pandemic has had a significant impact on the medicinal chemistry market for drug discovery. While it accelerated research for COVID-19 treatments and vaccines, it disrupted non-COVID drug development, causing delays and reallocating resources. Lockdowns affected laboratory work and clinical trials. Collaboration and data sharing have increased to expedite research. Regulatory agencies adapted, expediting approvals. The long-term impact includes changes in research priorities, emphasising vaccine development and antiviral therapies, as well as a renewed emphasis on global health security.

The Biologics segment is expected to be the largest during the forecast period

The Biologics segment is estimated to hold the largest share. Biologics are a class of medicinal products derived from biological sources. These complex molecules, such as monoclonal antibodies, proteins, and nucleic acids, are focused on the development of therapeutic drugs. Biologics are designed to target specific disease pathways with high precision, offering effective treatments for various conditions, including autoimmune disorders, cancer, and rare diseases. Moreover, the development of biologics involves intricate medicinal chemistry, genetic engineering, and biotechnology techniques. Biologics have revolutionised healthcare, providing innovative and often life-changing treatment options, and represent a rapidly growing and evolving sector within the pharmaceutical industry. 

The Oncology segment is expected to have the highest CAGR during the forecast period

The Oncology segment is anticipated to have lucrative growth during the forecast period. Oncology is the branch of medicine and medical science that focuses on the discovery and development of drugs specifically for the diagnosis, prevention, and treatment of various forms of cancer. It is a critical area of research due to the prevalence and complexity of cancer. Medicinal chemists in the oncology field design and optimise molecules that target cancer cells, disrupt disease pathways, or enhance the body's ability to fight cancer. In addition, these therapies can include traditional chemotherapies, targeted therapies, immunotherapies, and novel approaches, driving continuous innovation to combat one of the world's most challenging health issues

Region with largest share:

Asia Pacific commanded the largest market share during the extrapolated period. The Asia-Pacific region plays a vital role in the medicinal chemistry market for drug discovery. It encompasses diverse countries with growing healthcare infrastructure and research capabilities. China, India, Japan, and South Korea are key hubs for pharmaceutical research and production. The region benefits from lower research costs, attracting investment from global pharmaceutical companies. Furthermore, Asia-Pacific offers opportunities for collaborative research, clinical trials, and access to a vast patient population for testing new drugs, making it a dynamic and significant segment of the global medicinal chemistry for drug discovery market.

Region with highest CAGR:

North America is expected to witness profitable growth over the projection period. In the United States and Canada, which host many leading pharmaceutical and biotechnology companies, renowned research institutions, and robust healthcare infrastructure, North America is a hub for innovation, with a focus on cutting-edge technologies like genomics and biologics. Moreover, the region benefits from strong intellectual property protection, facilitating drug development and commercialization. North America remains at the forefront of drug discovery, often setting global trends and standards in pharmaceutical research and development. 

Key players in the market

Some of the key players in the Medicinal Chemistry For Drug Discovery Market include Eurofins Scientific, WuXi Apptec, Labcorp Drug Development, Charles River, Evotec SE, Charles River, Piramal Pharma Solutions, Certara USA, Pfizer, Inc., Sygnature Discovery Limited, Jubilant Biosys Ltd., Malvern Panalytical Ltd, Taros Chemicals GmbH & Co. KG, Nereid Therapeutics Inc., Genscript Biotech Corporation, BioBlocks, Inc., Domainex, Aurelia Biosciences Ltd., Thermo Fisher Scientific Inc. and Spectris Plc.

Key Developments:

In October 2023, Pfizer Inc. and BioNTech SE announced positive topline results from a Phase 1/2 study evaluating the safety, tolerability and immunogenicity of mRNA-based combination vaccine candidates for influenza and COVID-19 among healthy adults 18 to 64 years of age. The data from the trial showed that the companies' lead formulations demonstrated robust immune responses to influenza A, influenza B, and SARS-CoV-2 strains.

In October 2023, Pfizer Inc. announced that the U.S. Food and Drug Administration (FDA) has approved PENBRAYA (meningococcal groups A, B, C, W and Y vaccine), the first and only pentavalent vaccine that provides coverage against the most common serogroups causing meningococcal disease in adolescents and young adults 10 through 25 years of age.

In October 2023, Labcorp, a global leader of innovative and comprehensive laboratory services, announced the launch and national availability of its ATN Profile, a blood-based test that combines three, well-researched blood biomarkers to identify and assess biological changes associated with Alzheimer's disease – amyloid plaques, tau tangles and neurodegeneration (ATN) – which can help accelerate the path to diagnosis and intervention. 

In October 2023, Labcorp, a global leader of innovative and comprehensive laboratory services, announced that it acquired Baystate Health, Inc.'s  outreach laboratory business and select operating assets, including laboratory service centers operated by Baystate Health throughout Massachusetts..

Processes Covered:
• Target Selection 
• Candidate Validation 
• Hit-to-Lead Identification 
• Lead Optimization 

Designs Covered:
• Fragment-Based Variation 
• Diversity Oriented Synthesis 
• Structure Based Drug Design 
• Natural Products 
• Chemogenomics 
• Other Designs 

Drug Types Covered:
• Biologics
• Small Molecules

Therapeutic Areas Covered:
• Oncology
• Infectious and Immune System Diseases 
• Neurology 
• Digestive System Diseases 
• Cardiovascular Diseases 
• Other Therapeutic Areas 

Regions Covered:
• Contract Research Organization  
• Academic and Research Institutes  
• Pharmaceutical and Biotechnology Companies  
• Other End Users 
 
Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan        
o China        
o India        
o Australia  
o New Zealand
o South Korea
o Rest of Asia Pacific    
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa 
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2021, 2022, 2023, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings: 
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary     
       
2 Preface      
 2.1 Abstract     
 2.2 Stake Holders    
 2.3 Research Scope    
 2.4 Research Methodology   
  2.4.1 Data Mining   
  2.4.2 Data Analysis   
  2.4.3 Data Validation   
  2.4.4 Research Approach   
 2.5 Research Sources    
  2.5.1 Primary Research Sources  
  2.5.2 Secondary Research Sources  
  2.5.3 Assumptions   
       
3 Market Trend Analysis    
 3.1 Introduction    
 3.2 Drivers     
 3.3 Restraints    
 3.4 Opportunities    
 3.5 Threats     
 3.6 End User Analysis    
 3.7 Emerging Markets    
 3.8 Impact of Covid-19    
       
4 Porters Five Force Analysis    
 4.1 Bargaining power of suppliers   
 4.2 Bargaining power of buyers   
 4.3 Threat of substitutes   
 4.4 Threat of new entrants   
 4.5 Competitive rivalry    
       
5 Global Medicinal Chemistry For Drug Discovery Market, By Process
 5.1 Introduction    
 5.2 Target Selection    
 5.3 Candidate Validation   
 5.4 Hit-to-Lead Identification   
 5.5 Lead Optimization    
       
6 Global Medicinal Chemistry For Drug Discovery Market, By Design
 6.1 Introduction    
 6.2 Fragment-Based Variation   
 6.3 Diversity Oriented Synthesis   
 6.4 Structure Based Drug Design   
 6.5 Natural Products    
 6.6 Chemogenomics    
 6.7 Other Designs    
       
7 Global Medicinal Chemistry For Drug Discovery Market, By Drug Type
 7.1 Introduction    
 7.2 Biologics     
 7.3 Small Molecules    
       
8 Global Medicinal Chemistry For Drug Discovery Market, By Therapeutic Area
 8.1 Introduction    
 8.2 Oncology     
 8.3 Infectious and Immune System Diseases  
 8.4 Neurology    
 8.5 Digestive System Diseases   
 8.6 Cardiovascular Diseases   
 8.7 Other Therapeutic Areas   
       
9 Global Medicinal Chemistry For Drug Discovery Market, By End User
 9.1 Introduction    
 9.2 Contract Research Organization  
 9.3 Academic and Research Institutes  
 9.4 Pharmaceutical and Biotechnology Companies 
 9.5 Other End Users    
       
10 Global Medicinal Chemistry For Drug Discovery Market, By Geography
 10.1 Introduction    
 10.2 North America    
  10.2.1 US    
  10.2.2 Canada    
  10.2.3 Mexico    
 10.3 Europe     
  10.3.1 Germany    
  10.3.2 UK    
  10.3.3 Italy    
  10.3.4 France    
  10.3.5 Spain    
  10.3.6 Rest of Europe   
 10.4 Asia Pacific    
  10.4.1 Japan    
  10.4.2 China    
  10.4.3 India    
  10.4.4 Australia    
  10.4.5 New Zealand   
  10.4.6 South Korea   
  10.4.7 Rest of Asia Pacific   
 10.5 South America    
  10.5.1 Argentina   
  10.5.2 Brazil    
  10.5.3 Chile    
  10.5.4 Rest of South America  
 10.6 Middle East & Africa   
  10.6.1 Saudi Arabia   
  10.6.2 UAE    
  10.6.3 Qatar    
  10.6.4 South Africa   
  10.6.5 Rest of Middle East & Africa  
       
11 Key Developments     
 11.1 Agreements, Partnerships, Collaborations and Joint Ventures
 11.2 Acquisitions & Mergers   
 11.3 New Product Launch   
 11.4 Expansions    
 11.5 Other Key Strategies   
       
12 Company Profiling     
 12.1 Eurofins Scientific    
 12.2 WuXi Apptec    
 12.3 Labcorp Drug Development   
 12.4 Charles River    
 12.5 Evotec SE     
 12.6 Charles River    
 12.7 Piramal Pharma Solutions   
 12.8 Certara USA    
 12.9 Pfizer, Inc.    
 12.10 Sygnature Discovery Limited   
 12.11 Jubilant Biosys Ltd.    
 12.12 Malvern Panalytical Ltd    
 12.13 Taros Chemicals GmbH & Co. KG  
 12.14 Nereid Therapeutics Inc.   
 12.15 Genscript Biotech Corporation   
 12.16 BioBlocks, Inc.    
 12.17 Domainex    
 12.18 Aurelia Biosciences Ltd.   
 12.19 Thermo Fisher Scientific Inc.   
 12.20 Spectris Plc    
       
List of Tables      
1 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Region (2021-2030) ($MN)
2 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Process (2021-2030) ($MN)
3 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Target Selection (2021-2030) ($MN)
4 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Candidate Validation (2021-2030) ($MN)
5 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Hit-to-Lead Identification (2021-2030) ($MN)
6 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Lead Optimization (2021-2030) ($MN)
7 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Design (2021-2030) ($MN)
8 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Fragment-Based Variation (2021-2030) ($MN)
9 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Diversity Oriented Synthesis (2021-2030) ($MN)
10 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Structure Based Drug Design (2021-2030) ($MN)
11 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Natural Products (2021-2030) ($MN)
12 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Chemogenomics (2021-2030) ($MN)
13 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Other Designs (2021-2030) ($MN)
14 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Drug Type (2021-2030) ($MN)
15 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Biologics (2021-2030) ($MN)
16 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Small Molecules (2021-2030) ($MN)
17 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Therapeutic Area (2021-2030) ($MN)
18 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Oncology (2021-2030) ($MN)
19 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Infectious and Immune System Diseases (2021-2030) ($MN)
20 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Neurology (2021-2030) ($MN)
21 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Digestive System Diseases (2021-2030) ($MN)
22 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Cardiovascular Diseases (2021-2030) ($MN)
23 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
24 Global Medicinal Chemistry For Drug Discovery Market Outlook, By End User (2021-2030) ($MN)
25 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Contract Research Organization (2021-2030) ($MN)
26 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
27 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
28 Global Medicinal Chemistry For Drug Discovery Market Outlook, By Other End Users (2021-2030) ($MN)
       
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures

RESEARCH METHODOLOGY


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.


Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.


For more details about research methodology, kindly write to us at info@strategymrc.com

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