Peptide Synthesis Market
Peptide Synthesis Market Forecasts to 2030 - Global Analysis By Product (Equipment, Reagents, Consumables and Other Products), Technology, Application, End User and By Geography
Years Covered |
2021-2030 |
Estimated Year Value (2023) |
US $5.1 BN |
Projected Year Value (2030) |
US $10.2 BN |
CAGR (2023 - 2030) |
10.2% |
Regions Covered |
North America, Europe, Asia Pacific, South America, and Middle East & Africa |
Countries Covered |
US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa |
Largest Market |
North America |
Highest Growing Market |
Asia Pacific |
According to Stratistics MRC, the Global Peptide Synthesis Market is accounted for $5.1 billion in 2023 and is expected to reach $10.2 billion by 2030 growing at a CAGR of 10.2% during the forecast period. The chemical process of forming peptides, which are short chains of amino acids joined by peptide bonds, is known as peptide synthesis. It entails assembling amino acids step-by-step in a predetermined order, and controlling the reaction frequently necessitates the preservation of particular functional groups. There are several ways to synthesize peptides, including solid-phase synthesis, solution-phase synthesis, and recombinant DNA technology.
According to Clinical Trials.gov, 21 peptide drugs were in development for the treatment of COVID-19, including 15 synthetic peptides for acute respiratory distress syndrome (ARDS), a life-threatening condition in which the lungs are unable to provide enough oxygen to the body's vital organs, and other respiratory illnesses caused by SARS-Cov-2 infection.
Market Dynamics:
Driver:
Development of personalized medicines
The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. The idea of customized medicine is made possible by the ability to customize peptides to fit certain patient profiles. They provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Restraint:
Problems related to the administrative route
The majority of therapeutic peptides are administered by the parenteral route because of insufficient absorption from the gastrointestinal tract. Peptide medications have a limited oral bioavailability mostly due to pre-systemic enzymatic breakdown. Additionally, the large molecular weight and charged functional groups of these medicines sometimes impede their absorption. These features result in the majority of peptides taken orally having limited bioavailability and brief half-lives. Hence, it can be considered a challenge for the market.
Opportunity:
Advancement in therapeutics for rare diseases
Peptides could be able to cure orphan illnesses and unusual genetic problems. The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. Peptides provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Threat:
Purification and quality control
Peptides must be obtained with a high degree of purity in order for research and therapeutic applications to be effective. High-performance liquid chromatography (HPLC) is one of the purification techniques that might take a long time and need to be optimized for every peptide sequence. For synthesized peptides to be accurate, consistent, and safe, quality control procedures are necessary. The market may find it difficult to maintain effective purification procedures and high standards of quality.
Covid-19 Impact:
The pandemic affected the availability of raw materials and equipment required for peptide synthesis by upsetting supply lines around the world. The total distribution and availability of synthesized peptides were impacted by production and shipping delays. The pandemic caused a major shift in the focus of healthcare. Demand for some peptide-based medications or vaccines associated with COVID-19 research may have increased, while interruptions in non-essential healthcare services may have resulted in a decline in demand for other peptide products.
The reagents segment is expected to be the largest during the forecast period
The reagents segment is expected to be the largest during the forecast period. The process of peptide synthesis entails joining amino acids chemically to form peptides. Synthesis times can be shortened by using certain chemicals that promote quicker and more effective peptide bond formation. By reducing side effects and contaminants, using the right reagent can result in a peptide that is more pure. Certain reagents help with the precise coupling of amino acids without producing undesirable reactions since they are very selective.
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period. Peptide treatments are the subject of more study and development because they are less toxic, efficacious, and cost-effective. Rapid technical improvements in peptide synthesizers and a robust pipeline of peptide therapies are the main factors driving the peptide synthesis industry in pharmaceutical and biotechnology firms.
Region with largest share:
North America is projected to hold the largest market share during the forecast period. Growth in the production of customized therapies, substantial research in the fields of genomics and proteomics, and greater investments in the creation of structure-based medicine designs have all helped the regional market. Additionally, the market will expand due to the increased awareness of the accessible peptide synthesis methods.
Region with highest CAGR:
Asia Pacific is projected to hold the highest CAGR over the forecast period. The market is expected to develop significantly as a result of the increase in investments made by important players. Furthermore, it is expected that the region's market will grow due to rising awareness of novel peptide treatments, rising healthcare costs, the availability of more cutting-edge healthcare facilities, and significant investments made by the major players in the industry to create new peptide synthesis technologies.
Key players in the market
Some of the key players in Peptide Synthesis market include Biotage, Genscript Biotech, Thermo Fisher Scientific, Merck KGaA, Creative Diagnostics, CEM Corporation, Bachem Holdings, PuroSynth, Syngene, Lonza, Polypeptide Group, Novo Nordisk A/S, MP Biomedicals and Evonik.
Key Developments:
In January 2023, Merck announced an agreement to acquire the peptide synthesis company Asymchem. This acquisition will give Merck access to Asymchem's expertise in peptide synthesis and its global manufacturing network.
In December 2022, Thermo Fisher announced an agreement to acquire the peptide synthesis company Protagen. This acquisition will give Thermo Fisher access to Protagen's expertise in peptide synthesis and its global manufacturing network.
Products Covered:
• Equipment
• Reagents
• Consumables
• Other Products
Technologies Covered:
• Solution-Phase Peptide Synthesis
• Solid-Phase Peptide Synthesis
• Hybrid & Recombinant Technology
Applications Covered:
• Therapeutics
• Diagnosis
• Research
• Other Applications
End Users Covered:
• Pharmaceutical and Biotechnology Companies
• Contract Manufacturing Organization
• Academic
• Other End Users
Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa
What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2021, 2022, 2023, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements
Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances
Table of Contents
1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Anaysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Peptide Synthesis Market, By Product
5.1 Introduction
5.2 Equipment
5.2.1 Peptide Synthesizers
5.2.2 Chromatography Equipment
5.2.3 Lyophilizers
5.3 Reagents
5.4 Consumables
5.5 Other Products
6 Global Peptide Synthesis Market, By Technology
6.1 Introduction
6.2 Solution-Phase Peptide Synthesis
6.3 Solid-Phase Peptide Synthesis
6.4 Hybrid & Recombinant Technology
7 Global Peptide Synthesis Market, By Application
7.1 Introduction
7.2 Therapeutics
7.2.1 Metabolic Disorders
7.2.2 Cancer
7.2.3 Respiratory Disorders
7.2.4 Cardiovascular Disorders
7.2.5 Gastrointestinal Disorders
7.2.6 Infectious Diseases
7.2.7 Dermatology Disorders
7.2.8 Pain Management
7.2.9 CNS Disorders
7.2.10 Renal Disorders
7.2.11 Other Therapeutics
7.3 Diagnosis
7.4 Research
7.5 Other Applications
8 Global Peptide Synthesis Market, By End User
8.1 Introduction
8.2 Pharmaceutical and Biotechnology Companies
8.3 Contract Manufacturing Organization
8.4 Academic
8.5 Other End Users
9 Global Peptide Synthesis Market, By Geography
9.1 Introduction
9.2 North America
9.2.1 US
9.2.2 Canada
9.2.3 Mexico
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 Italy
9.3.4 France
9.3.5 Spain
9.3.6 Rest of Europe
9.4 Asia Pacific
9.4.1 Japan
9.4.2 China
9.4.3 India
9.4.4 Australia
9.4.5 New Zealand
9.4.6 South Korea
9.4.7 Rest of Asia Pacific
9.5 South America
9.5.1 Argentina
9.5.2 Brazil
9.5.3 Chile
9.5.4 Rest of South America
9.6 Middle East & Africa
9.6.1 Saudi Arabia
9.6.2 UAE
9.6.3 Qatar
9.6.4 South Africa
9.6.5 Rest of Middle East & Africa
10 Key Developments
10.1 Agreements, Partnerships, Collaborations and Joint Ventures
10.2 Acquisitions & Mergers
10.3 New Product Launch
10.4 Expansions
10.5 Other Key Strategies
11 Company Profiling
11.1 Biotage
11.2 Genscript Biotech
11.3 Thermo Fisher Scientific
11.4 Merck KGaA
11.5 Creative Diagnostics
11.6 CEM Corporation
11.7 Bachem Holdings
11.8 PuroSynth
11.9 Syngene
11.10 Lonza
11.11 Polypeptide Group
11.12 Novo Nordisk A/S
11.13 MP Biomedicals
11.14 Evonik
List of Tables
1 Global Peptide Synthesis Market Outlook, By Region (2021-2030) ($MN)
2 Global Peptide Synthesis Market Outlook, By Product (2021-2030) ($MN)
3 Global Peptide Synthesis Market Outlook, By Equipment (2021-2030) ($MN)
4 Global Peptide Synthesis Market Outlook, By Peptide Synthesizers (2021-2030) ($MN)
5 Global Peptide Synthesis Market Outlook, By Chromatography Equipment (2021-2030) ($MN)
6 Global Peptide Synthesis Market Outlook, By Lyophilizers (2021-2030) ($MN)
7 Global Peptide Synthesis Market Outlook, By Reagents (2021-2030) ($MN)
8 Global Peptide Synthesis Market Outlook, By Consumables (2021-2030) ($MN)
9 Global Peptide Synthesis Market Outlook, By Other Products (2021-2030) ($MN)
10 Global Peptide Synthesis Market Outlook, By Technology (2021-2030) ($MN)
11 Global Peptide Synthesis Market Outlook, By Solution-Phase Peptide Synthesis (2021-2030) ($MN)
12 Global Peptide Synthesis Market Outlook, By Solid-Phase Peptide Synthesis (2021-2030) ($MN)
13 Global Peptide Synthesis Market Outlook, By Hybrid & Recombinant Technology (2021-2030) ($MN)
14 Global Peptide Synthesis Market Outlook, By Application (2021-2030) ($MN)
15 Global Peptide Synthesis Market Outlook, By Therapeutics (2021-2030) ($MN)
16 Global Peptide Synthesis Market Outlook, By Metabolic Disorders (2021-2030) ($MN)
17 Global Peptide Synthesis Market Outlook, By Cancer (2021-2030) ($MN)
18 Global Peptide Synthesis Market Outlook, By Respiratory Disorders (2021-2030) ($MN)
19 Global Peptide Synthesis Market Outlook, By Cardiovascular Disorders (2021-2030) ($MN)
20 Global Peptide Synthesis Market Outlook, By Gastrointestinal Disorders (2021-2030) ($MN)
21 Global Peptide Synthesis Market Outlook, By Infectious Diseases (2021-2030) ($MN)
22 Global Peptide Synthesis Market Outlook, By Dermatology Disorders (2021-2030) ($MN)
23 Global Peptide Synthesis Market Outlook, By Pain Management (2021-2030) ($MN)
24 Global Peptide Synthesis Market Outlook, By CNS Disorders (2021-2030) ($MN)
25 Global Peptide Synthesis Market Outlook, By Renal Disorders (2021-2030) ($MN)
26 Global Peptide Synthesis Market Outlook, By Other Therapeutics (2021-2030) ($MN)
27 Global Peptide Synthesis Market Outlook, By Diagnosis (2021-2030) ($MN)
28 Global Peptide Synthesis Market Outlook, By Research (2021-2030) ($MN)
29 Global Peptide Synthesis Market Outlook, By Other Applications (2021-2030) ($MN)
30 Global Peptide Synthesis Market Outlook, By End User (2021-2030) ($MN)
31 Global Peptide Synthesis Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
32 Global Peptide Synthesis Market Outlook, By Contract Manufacturing Organization (2021-2030) ($MN)
33 Global Peptide Synthesis Market Outlook, By Academic (2021-2030) ($MN)
34 Global Peptide Synthesis Market Outlook, By End Users (2021-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
List of Figures
RESEARCH METHODOLOGY
We at ‘Stratistics’ opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.
Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.
Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.
Data Mining
The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.
Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.
Data Analysis
From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:
- Product Lifecycle Analysis
- Competitor analysis
- Risk analysis
- Porters Analysis
- PESTEL Analysis
- SWOT Analysis
The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.
Data Validation
The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.
We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.
The data validation involves the primary research from the industry experts belonging to:
- Leading Companies
- Suppliers & Distributors
- Manufacturers
- Consumers
- Industry/Strategic Consultants
Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.
For more details about research methodology, kindly write to us at info@strategymrc.com
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