Tangential Flow Filtration
PUBLISHED: 2024 ID: SMRC27630
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Tangential Flow Filtration

Tangential Flow Filtration Market Forecasts to 2030 - Global Analysis By Product (Systems, Membrane Filters and Other Products), Technology, Application, End User and By Geography

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4.4 (70 reviews)
Published: 2024 ID: SMRC27630

This report covers the impact of COVID-19 on this global market
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According to Stratistics MRC, the Global Tangential Flow Filtration Market is accounted for $2.0 billion in 2024 and is expected to reach $4.4 billion by 2030 growing at a CAGR of 14.4% during the forecast period. A filtration method called Tangential Flow Filtration (TFF) is used in the food, pharmaceutical, and biotechnology sectors to separate and purify biomolecules. It reduces particle accumulation and increases membrane lifespan and efficiency by using feed solution to flow parallel to the filter membrane surface. TFF can be used for viral purification, cell harvesting, concentration, diafiltration, fractionation, and product stream elimination. It is crucial for bioprocessing applications because of its excellent selectivity, low fouling, and rapid processing speed.

Market Dynamics: 

Driver: 

Increasing demand in biotechnology and pharmaceutical industries

The increasing production of biologics, such as monoclonal antibodies, vaccines, and gene therapies, necessitates efficient purification processes. TFF technology is crucial for concentrating and purifying these complex biomolecules, making it a critical technology in biopharmaceutical manufacturing. As more biopharmaceutical companies outsource to contract manufacturing organizations, there is a growing reliance on TFF technology for large-scale production boosting market demand. 

Restraint:

High initial capital investment

The high initial costs of TFF systems can deter small and medium-sized enterprises (SMEs) from adopting this technology, as they may lack the financial resources to invest in sophisticated equipment. This can limit their ability to compete effectively in the biopharmaceutical market, where TFF is increasingly essential. Additionally, these high initial costs can result in slower market adoption, delaying potential advancements in bioprocessing efficiency and effectiveness.

Opportunity:

Advancements in filtration technology

The increasing demand for biologics and biosimilars has led to increased investments in filtration filtration (TFF) technologies. These systems enable biopharmaceutical companies to meet production demands while ensuring product quality and regulatory compliance. The integration of AI and IoT in TFF systems enhances operational efficiency, allowing real-time monitoring, optimization, and maintenance prediction in various sectors.

Threat:

Membrane fouling and cleaning challenges

Membrane fouling can lead to reduced flow rates and lower filtration efficiency, resulting in longer processing times and hindering bioprocessing operations productivity. This can negatively impact manufacturers' bottom line. Regular cleaning of fouled membranes is necessary for performance maintenance, but it requires downtime that can disrupt production schedules, slowing output and increasing labor costs.

Covid-19 Impact: 

The COVID-19 pandemic had a mixed impact on the Tangential Flow Filtration (TFF) market. The surge in vaccine development and biopharmaceutical production during the crisis significantly increased demand for TFF technologies, facilitating rapid purification and concentration processes. Additionally, some smaller companies faced financial strain, limiting their investment in TFF systems. Overall, while the pandemic accelerated growth in the TFF market due to heightened demand, it also introduced operational challenges.

The membrane filters segment is expected to be the largest during the forecast period

Over the forecasted timeframe, the membrane filters segment is anticipated to dominate the market share because advanced materials like polyethersulfone and polyvinylidene fluoride offer improved flux rates and selectivity, facilitating efficient separation and purification of biomolecules. These filters also enhance product recovery and purity, minimizing contaminant carryover and enhancing product quality thus boosting the market growth.

The nanofiltration segment is expected to have the highest CAGR during the forecast period

The nanofiltration segment is projected to have the highest CAGR in the tangential flow filtration market during the extrapolated period as it enhances the application range of Total Filtration (TFF) systems in industries like biopharmaceuticals, food and beverage, and wastewater treatment, driving market growth. It also improves bioprocessing efficiency by reducing fouling and enhancing throughput, especially in biopharmaceutical manufacturing. 

Region with largest share:

The North America region is projected to account for the largest market share during the forecast period due to significant R&D investments by academic and industrial entities, which demand efficient filtration technologies for protein purification and cell culture. The expansion of Contract Manufacturing Organizations (CMOs), which offer outsourced manufacturing services to biopharmaceutical companies, has also increased demand for TFF solutions, as these organizations require scalable and efficient filtration processes.

Region with highest CAGR:

The Asia Pacific region is expected to register the highest growth rate over the forecast period because governments in Asia Pacific countries are boosting biotechnology and pharmaceutical industries through policies, funding, and infrastructure development, fostering the growth of Total Fatigue (TFF) technologies. This growth is fueled by the rise of biotechnology startups, who seek efficient and scalable purification processes to market their innovative products.

Key players in the market

Some of the key players in Tangential Flow Filtration Market include ABEC, Inc., Alfa Laval, Andritz Group, Danaher Corporation, FUJIFILM Wako Pure Chemical Corporation, Meissner Filtration Products, Inc., Merck KGaA, Parker Hannifin Corporation, Repligen Corporation, Sartorius AG, Solaris Biotechnology SRL, Sterlitech Corporation and Synder Filtration, Inc.

Key Developments:

In July 2024, Danaher Corporation announced the launch of two new Clinical Laboratory Improvement Amendments (CLIA) and College of American Pathologists (CAP)-certified labs intended to accelerate the development of Companion Diagnostics (CDx) and Complementary Diagnostics (CoDx).

In July 2024, Danaher Corporation launched a research collaboration with Stanford University's Department of Bioengineering intended to shape the future of cancer drug screening through ""smart microscopy.""

In July 2024, Parker Hannifin Corporation announced it has signed an agreement to divest its North America Composites and Fuel Containment (CFC) Division to private investment firm SK Capital Partners.

Products Covered:
• Systems
• Membrane Filters
• Other Products 

Technologies Covered:
• Ultrafiltration 
• Microfiltration 
• Nanofiltration 
• Other Technologies 

Applications Covered:
• Protein Purification
• Vaccine &Vaccine And Viral Vectors Viral Vectors
• Antibody Purification
• Raw Material Filtration
• Other Applications  

End Users Covered:
• Biotechnology & Pharmaceutical Companies 
• Academic & Research Institutes 
• Food & Beverage Processing Companies 
• Water Treatment Facilities 
• Other End Users   

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan        
o China        
o India        
o Australia  
o New Zealand
o South Korea
o Rest of Asia Pacific    
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa 
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2022, 2023, 2024, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings: 
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary          
            
2 Preface           
 2.1 Abstract          
 2.2 Stake Holders         
 2.3 Research Scope         
 2.4 Research Methodology        
  2.4.1 Data Mining        
  2.4.2 Data Analysis        
  2.4.3 Data Validation        
  2.4.4 Research Approach        
 2.5 Research Sources         
  2.5.1 Primary Research Sources       
  2.5.2 Secondary Research Sources       
  2.5.3 Assumptions        
            
3 Market Trend Analysis         
 3.1 Introduction         
 3.2 Drivers          
 3.3 Restraints          
 3.4 Opportunities         
 3.5 Threats          
 3.6 Product Analysis         
 3.7 Technology Analysis         
 3.8 Application Analysis         
 3.9 End User Analysis         
 3.10 Emerging Markets         
 3.11 Impact of Covid-19         
            
4 Porters Five Force Analysis         
 4.1 Bargaining power of suppliers        
 4.2 Bargaining power of buyers        
 4.3 Threat of substitutes         
 4.4 Threat of new entrants        
 4.5 Competitive rivalry         
            
5 Global Tangential Flow Filtration Market, By Product       
 5.1 Introduction         
 5.2 Systems          
  5.2.1 Single-use Tangential Flow Filtration Systems     
  5.2.2 Reusable Tangential Flow Filtration Systems     
 5.3 Membrane Filters         
  5.3.1 Polyethersulfone (PES)       
  5.3.2 Polyvinylidene Difluoride (PVDF)       
  5.3.3 Polytetrafluoroethylene (PTFE)       
  5.3.4 Mixed Cellulose Ester & Cellulose Acetate      
  5.3.5 Polycarbonate Tracked Etched (PCTE)      
  5.3.6 Regenerated Cellulose       
 5.4 Other Products         
            
6 Global Tangential Flow Filtration Market, By Technology      
 6.1 Introduction         
 6.2 Ultrafiltration         
 6.3 Microfiltration         
 6.4 Nanofiltration         
 6.5 Other Technologies         
            
7 Global Tangential Flow Filtration Market, By Application      
 7.1 Introduction         
 7.2 Protein Purification         
 7.3 Vaccine &Vaccine And Viral Vectors Viral Vectors      
 7.4 Antibody Purification         
 7.5 Raw Material Filtration        
 7.6 Other Applications         
            
8 Global Tangential Flow Filtration Market, By End User      
 8.1 Introduction         
 8.2 Biotechnology & Pharmaceutical Companies      
 8.3 Academic & Research Institutes        
 8.4 Food & Beverage Processing Companies       
 8.5 Water Treatment Facilities        
 8.6 Other End Users         
            
9 Global Tangential Flow Filtration Market, By Geography      
 9.1 Introduction         
 9.2 North America         
  9.2.1 US         
  9.2.2 Canada         
  9.2.3 Mexico         
 9.3 Europe          
  9.3.1 Germany         
  9.3.2 UK         
  9.3.3 Italy         
  9.3.4 France         
  9.3.5 Spain         
  9.3.6 Rest of Europe        
 9.4 Asia Pacific         
  9.4.1 Japan         
  9.4.2 China         
  9.4.3 India         
  9.4.4 Australia         
  9.4.5 New Zealand        
  9.4.6 South Korea        
  9.4.7 Rest of Asia Pacific        
 9.5 South America         
  9.5.1 Argentina         
  9.5.2 Brazil         
  9.5.3 Chile         
  9.5.4 Rest of South America       
 9.6 Middle East & Africa         
  9.6.1 Saudi Arabia        
  9.6.2 UAE         
  9.6.3 Qatar         
  9.6.4 South Africa        
  9.6.5 Rest of Middle East & Africa       
            
10 Key Developments          
 10.1 Agreements, Partnerships, Collaborations and Joint Ventures     
 10.2 Acquisitions & Mergers        
 10.3 New Product Launch         
 10.4 Expansions         
 10.5 Other Key Strategies         
            
11 Company Profiling          
 11.1 ABEC, Inc.         
 11.2 Alfa Laval          
 11.3 Andritz Group         
 11.4 Danaher Corporation        
 11.5 FUJIFILM Wako Pure Chemical Corporation      
 11.6 Meissner Filtration Products, Inc.       
 11.7 Merck KGaA         
 11.8 Parker Hannifin Corporation        
 11.9 Repligen Corporation        
 11.10 Sartorius AG         
 11.11 Solaris Biotechnology SRL        
 11.12 Sterlitech Corporation        
 11.13 Synder Filtration, Inc.        
            
List of Tables           
1 Global Tangential Flow Filtration Market Outlook, By Region (2022-2030) ($MN)    
2 Global Tangential Flow Filtration Market Outlook, By Product (2022-2030) ($MN)    
3 Global Tangential Flow Filtration Market Outlook, By Systems (2022-2030) ($MN)    
4 Global Tangential Flow Filtration Market Outlook, By Single-use Tangential Flow Filtration Systems (2022-2030) ($MN) 
5 Global Tangential Flow Filtration Market Outlook, By Reusable Tangential Flow Filtration Systems (2022-2030) ($MN) 
6 Global Tangential Flow Filtration Market Outlook, By Membrane Filters (2022-2030) ($MN)   
7 Global Tangential Flow Filtration Market Outlook, By Polyethersulfone (PES) (2022-2030) ($MN)   
8 Global Tangential Flow Filtration Market Outlook, By Polyvinylidene Difluoride (PVDF) (2022-2030) ($MN)  
9 Global Tangential Flow Filtration Market Outlook, By Polytetrafluoroethylene (PTFE) (2022-2030) ($MN)  
10 Global Tangential Flow Filtration Market Outlook, By Mixed Cellulose Ester & Cellulose Acetate (2022-2030) ($MN) 
11 Global Tangential Flow Filtration Market Outlook, By Polycarbonate Tracked Etched (PCTE) (2022-2030) ($MN) 
12 Global Tangential Flow Filtration Market Outlook, By Regenerated Cellulose (2022-2030) ($MN)   
13 Global Tangential Flow Filtration Market Outlook, By Other Products (2022-2030) ($MN)   
14 Global Tangential Flow Filtration Market Outlook, By Technology (2022-2030) ($MN)    
15 Global Tangential Flow Filtration Market Outlook, By Ultrafiltration (2022-2030) ($MN)    
16 Global Tangential Flow Filtration Market Outlook, By Microfiltration (2022-2030) ($MN)   
17 Global Tangential Flow Filtration Market Outlook, By Nanofiltration (2022-2030) ($MN)    
18 Global Tangential Flow Filtration Market Outlook, By Other Technologies (2022-2030) ($MN)   
19 Global Tangential Flow Filtration Market Outlook, By Application (2022-2030) ($MN)    
20 Global Tangential Flow Filtration Market Outlook, By Protein Purification (2022-2030) ($MN)   
21 Global Tangential Flow Filtration Market Outlook, By Vaccine &Vaccine And Viral Vectors Viral Vectors (2022-2030) ($MN)
22 Global Tangential Flow Filtration Market Outlook, By Antibody Purification (2022-2030) ($MN)   
23 Global Tangential Flow Filtration Market Outlook, By Raw Material Filtration (2022-2030) ($MN)   
24 Global Tangential Flow Filtration Market Outlook, By Other Applications (2022-2030) ($MN)   
25 Global Tangential Flow Filtration Market Outlook, By End User (2022-2030) ($MN)    
26 Global Tangential Flow Filtration Market Outlook, By Biotechnology & Pharmaceutical Companies (2022-2030) ($MN) 
27 Global Tangential Flow Filtration Market Outlook, By Academic & Research Institutes (2022-2030) ($MN)  
28 Global Tangential Flow Filtration Market Outlook, By Food & Beverage Processing Companies (2022-2030) ($MN) 
29 Global Tangential Flow Filtration Market Outlook, By Water Treatment Facilities (2022-2030) ($MN)  
30 Global Tangential Flow Filtration Market Outlook, By Other End Users (2022-2030) ($MN)   
            
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures

RESEARCH METHODOLOGY


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.


Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.


For more details about research methodology, kindly write to us at info@strategymrc.com

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