Tangential Flow Filtration Market
PUBLISHED: 2023 ID: SMRC22876
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Tangential Flow Filtration Market

Tangential Flow Filtration Market Forecasts to 2028 - Global Analysis By Product (Membrane Filters, Reusable Systems and Other Products), Membrane Material (Nylon and Polyvinylidene Difluoride (PVDF) and Other Materials), Technique (Nanofiltration, Microfiltration, Ultrafiltration and Other Techniques), Application (Raw Material Filtration, Final Product Processing and Other Applications), End User and By Geography

4.4 (68 reviews)
4.4 (68 reviews)
Published: 2023 ID: SMRC22876

This report covers the impact of COVID-19 on this global market
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Years Covered

2020-2028

Estimated Year Value (2022)

US $1.5 BN

Projected Year Value (2028)

US $3.5 BN

CAGR (2022 - 2028)

15.2%

Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

Asia Pacific

Highest Growing Market

North America


According to Stratistics MRC, the Global Tangential Flow Filtration Market is accounted for $1.5 billion in 2022 and is expected to reach $3.5 billion by 2028 growing at a CAGR of 15.2% during the forecast period. Tangential flow filtration (TFF) is an effective approach for biomolecule purification and separation. Tangential flow filtration, also known as cross-flow filtration, is useful in both the upstream processing of cell harvesting and the downstream processing approach utilised in bio-manufacturing. It concentrates and desalts sample solutions in amounts ranging from 10 mL to thousands of litres. It is obtained through massive fractionation of harvest cell suspensions, tiny biomolecules, fermentation broths, and cell lysates.

According to a US-based independent, academic, non-profit research center, Tufts Center for the Study of Drug Development’s 2021 report, the global R&D spending by the largest publicly-traded biotech companies grew 13.7% annually, from $4.8 billion in 2001 to $55.0 billion in 2020.



Market Dynamics:

Driver:

Increasing utilization of tangential flow filtration

Typical tangential flow filtering processes include reverse osmosis and nanofiltration. In concentration and diafiltration techniques, tangential flow filtration is used. It increases a solution's concentration by removing liquids while maintaining the solute molecules. In diafiltration, tiny and giant particles separate, leaving the tinier particles behind without changing the total concentration at the end by washing out the rest of the salt with another buffer. This approach can also be used to reduce the concentration of a solution by washing away the remaining salts with water. Tangential flow filtration's increasing use is thus fuelling the growth of the Tangential Flow Filtration Market during the forecast period.

Restraint:

Requirement of high capital expenditure

High capital expenditure is necessary to construct and establish new manufacturing facilities, which may be difficult or easy to option out by small-scale businesses. Furthermore, the presence of cutting-edge technologies such as centrifugation, direct flow filtration, and pre-coat filtration is expected to hamper the worldwide tangential flow filtration market's expansion. Furthermore, numerous pharmaceutical corporations are constantly outsourcing manufacturing in order to effectively utilise foreign technology, experience, and capacity. As a result, the prices of finished items may rise, stifling market expansion.

Opportunity:

Rising therapeutic applications of recombinant proteins

Tangential flow filtration (TFF) is an immediate and effective technique for biomolecule separation and purification. It is useful in many scientific domains, including immunology, protein chemistry, molecular biology (DNA/RNA/oligonucleotides), biochemistry, and microbiology. TFF has been used to concentrate and desalt proteins and peptides, recover and purify antibodies or recombinant proteins from cell culture medium, and fractionate dilute protein mixtures over the years. Recombinant proteins have received substantial momentum for therapeutic uses as the treatment pattern has shifted towards focused therapy. The biopharmaceutical industry's tendency of commercialising recombinant proteins is projected to drive the growth of the tangential flow filtration market.

Threat:

Stifling competitiveness of market and presence of strict rules

The prevalence of rigorous government laws and regulations in the pharmaceutical business is expected to offer a challenge to the worldwide tangential flow filtration market during the forecast period. Furthermore, the market's presence of well-established and prominent competitors makes it difficult for new entrants to advertise their product offers and novel technology. Furthermore, important competitors in this market offer a wide selection of filtration products and have high levels of brand loyalty from customers, making it even more difficult for new entrants to establish a foothold in the industry.

Covid-19 Impact

The COVID 19 pandemic increased the global economic and social cost, prompting governments to increase vaccine development and manufacturing. Tangential flow filtration products are increasingly being used for COVID-19 research. To support downstream processes such as filtration and purification for vaccine development, various filtration techniques and materials are used. Moreover, some biopharmaceutical companies have incorporated several strategies to improve vaccine development and contain the pandemic. The COVID-19 epidemic has also created chances for filter manufacturers to expand their manufacturing facilities. As these filtering goods are utilised in the production of vaccines and other medicinal medications, the mass production of vaccines has favourably influenced the demand for tangential flow filtration products.

The membrane filters segment is expected to be the largest during the forecast period

The membrane filters segment is estimated to have a lucrative growth, due to the use of filtering systems in numerous industries, particularly the pharmaceutical industry, is the primary driver of this segment's growth. The segment's expansion is being driven by the ease of access to various types of filters such as PCTE, PVDF, PTFE, and PES. Furthermore, the availability of diverse membrane filtration areas and pore sizes for relevant processes encourages segment expansion.

The microfiltration segment is expected to have the highest CAGR during the forecast period

The microfiltration segment is anticipated to witness the fastest CAGR growth during the forecast period, due to the increased use of microfiltration techniques during cell separation procedures. Microfiltration membranes, on the other hand, are used to handle a variety of challenges such as microbial removal, protein separation, and membrane treatment, which is driving the segment's expansion. Furthermore, these membranes are available in a variety of pore diameters ranging from 0.1 to 10 m, which aids in limiting fouling and fractionating suspended particles. These factors will contribute to the segment's growth during the predicted period.

Region with highest share:

Asia Pacific is projected to hold the largest market share during the forecast period owing to the growing demand for biologics and medicines, considerable investments from domestic and international firms, and the expansion of CMOs in emerging markets such as China, Japan, and South Korea are all driving to the industry's growth. Furthermore, the focus on treatment modernization, healthcare infrastructure development, and need for low-cost pharmaceuticals would drive the growth of the TFF market in APAC.

Region with highest CAGR:

North America is projected to have the highest CAGR over the forecast period, owing to the increased bioprocessing activities to meet bio-therapeutic demand, increased frequency of chronic diseases and genetic abnormalities, expanding knowledge about treatment safety, and enhanced healthcare settings have all supported regional growth. Furthermore, the presence of a supportive government promotes development.



Key players in the market

Some of the key players profiled in the Tangential Flow Filtration Market include Andritz, Synder Filtration, INC., Merk KGAA, SPF Technologies, LLC, Parker Hannifin Corporation, Danaher Corporation, Sysbiotech Gmbh, Solaris Biotechnology SRL, Alfa Laval Corporate AB, Sartorius AG, Sterlitech Corporation, Koch Separation Solutions, Cole-Parmer Instrument Company, LLC, Repligen Corporation and Meissner Filtration Products, INC.

Key Developments:

In December 2021, Donaldson Company (US) acquired Solaris (Italy), a company that designs and manufactures bioprocessing equipment, including tangential flow filtration systems for use in biotechnology, and other life sciences markets. This acquisition will expand the company’s portfolio in the pharmaceutical industry.

In March 2020, Danaher acquired the biopharma business from General Electric Company. This division will be called Cytiva and will be a standalone company operating under the Danaher Life Sciences segment.

Products Covered:
• Membrane Filters
• Single-Use Systems
• Filtration Accessories
• Reusable Systems
• Other Products

Membrane Materials Covered:
• Nylon
• Polyvinylidene Difluoride (PVDF)
• Polyetrafluoroethylene (PTFE)
• Polyethersulfone (PES)
• Polycarbonate Tracked Etched (PCTE)
• Mixed Cellulose Ester & Cellulose Acetate (MCE & CA)
• Regenerated Cellulose
• Other Membrane Materials

Techniques Covered:
• Nanofiltration
• Microfiltration
• Ultrafiltration
• Other Techniques

Applications Covered:
• Raw Material Filtration
• Final Product Processing
• Cell Separation
• Water Purification
• Air Purification
• Other Applications

End Users Covered:
• Academic Institutes & Research Laboratories
• Pharmaceutical & Biotechnology Companies
• Contract Manufacturing Organisations (CMOs) & Contract Research Organisations (CROs)
• Other End Users

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions

3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19

4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 Global Tangential Flow Filtration Market, By Product
5.1 Introduction
5.2 Membrane Filters
5.2.1 Regenrated Cellulose
5.2.2 Polyethersukfone
5.2.3 Other Membrane Filters
5.3 Single-Use Systems
5.4 Filtration Accessories
5.5 Reusable Systems
5.6 Other Products

6 Global Tangential Flow Filtration Market, By Membrane Material
6.1 Introduction
6.2 Nylon
6.3 Polyvinylidene Difluoride (PVDF)
6.4 Polyetrafluoroethylene (PTFE)
6.5 Polyethersulfone (PES)
6.6 Polycarbonate Tracked Etched (PCTE)
6.7 Mixed Cellulose Ester & Cellulose Acetate (MCE & CA)
6.8 Regenerated Cellulose
6.9 Other Membrane Materials

7 Global Tangential Flow Filtration Market, By Technique
7.1 Introduction
7.2 Nanofiltration
7.3 Microfiltration
7.4 Ultrafiltration
7.5 Other Techniques

8 Global Tangential Flow Filtration Market, By Application
8.1 Introduction
8.2 Raw Material Filtration
8.2.1 Media Buffer Filtration
8.2.2 Prefiltration
8.2.3 Bioburden Testing
8.3 Final Product Processing
8.3.1 Active Pharmaceutical Ingredient (API) Filtration
8.3.2 Protein Purification
8.3.3 Vaccine and Antibody Processing
8.3.4 Formulation and Filling Solutions
8.3.5 Viral Clearance
8.4 Cell Separation
8.5 Water Purification
8.6 Air Purification
8.7 Other Applications

9 Global Tangential Flow Filtration Market, By End User
9.1 Introduction
9.2 Academic Institutes & Research Laboratories
9.3 Pharmaceutical & Biotechnology Companies
9.4 Contract Manufacturing Organisations (CMOs) & Contract Research Organisations (CROs)
9.5 Other End Users

10 Global Tangential Flow Filtration Market, By Geography
10.1 Introduction
10.2 North America
10.2.1 US
10.2.2 Canada
10.2.3 Mexico
10.3 Europe
10.3.1 Germany
10.3.2 UK
10.3.3 Italy
10.3.4 France
10.3.5 Spain
10.3.6 Rest of Europe
10.4 Asia Pacific
10.4.1 Japan
10.4.2 China
10.4.3 India
10.4.4 Australia
10.4.5 New Zealand
10.4.6 South Korea
10.4.7 Rest of Asia Pacific
10.5 South America
10.5.1 Argentina
10.5.2 Brazil
10.5.3 Chile
10.5.4 Rest of South America
10.6 Middle East & Africa
10.6.1 Saudi Arabia
10.6.2 UAE
10.6.3 Qatar
10.6.4 South Africa
10.6.5 Rest of Middle East & Africa

11 Key Developments
11.1 Agreements, Partnerships, Collaborations and Joint Ventures
11.2 Acquisitions & Mergers
11.3 New Product Launch
11.4 Expansions
11.5 Other Key Strategies

12 Company Profiling
12.1 Andritz
12.2 Synder Filtration, INC.
12.3 Merk KGAA
12.4 SPF Technologies, LLC
12.5 Parker Hannifin Corporation
12.6 Danaher Corporation
12.7 Sysbiotech Gmbh
12.8 Solaris Biotechnology SRL
12.9 Alfa Laval Corporate AB
12.10 Sartorius AG
12.11 Sterlitech Corporation
12.12 Koch Separation Solutions
12.13 Cole-Parmer Instrument Company, LLC
12.14 Repligen Corporation
12.15 Meissner Filtration Products, INC.

List of Tables
1 Global Tangential Flow Filtration Market Outlook, By Region (2020-2028) ($MN)
2 Global Tangential Flow Filtration Market Outlook, By Product (2020-2028) ($MN)
3 Global Tangential Flow Filtration Market Outlook, By Membrane Filters (2020-2028) ($MN)
4 Global Tangential Flow Filtration Market Outlook, By Regenrated Cellulose (2020-2028) ($MN)
5 Global Tangential Flow Filtration Market Outlook, By Polyethersukfone (2020-2028) ($MN)
6 Global Tangential Flow Filtration Market Outlook, By Other Membrane Filters (2020-2028) ($MN)
7 Global Tangential Flow Filtration Market Outlook, By Single-Use Systems (2020-2028) ($MN)
8 Global Tangential Flow Filtration Market Outlook, By Filtration Accessories (2020-2028) ($MN)
9 Global Tangential Flow Filtration Market Outlook, By Reusable Systems (2020-2028) ($MN)
10 Global Tangential Flow Filtration Market Outlook, By Other Products (2020-2028) ($MN)
11 Global Tangential Flow Filtration Market Outlook, By Membrane Material (2020-2028) ($MN)
12 Global Tangential Flow Filtration Market Outlook, By Nylon (2020-2028) ($MN)
13 Global Tangential Flow Filtration Market Outlook, By Polyvinylidene Difluoride (PVDF) (2020-2028) ($MN)
14 Global Tangential Flow Filtration Market Outlook, By Polyetrafluoroethylene (PTFE) (2020-2028) ($MN)
15 Global Tangential Flow Filtration Market Outlook, By Polyethersulfone (PES) (2020-2028) ($MN)
16 Global Tangential Flow Filtration Market Outlook, By Polycarbonate Tracked Etched (PCTE) (2020-2028) ($MN)
17 Global Tangential Flow Filtration Market Outlook, By Mixed Cellulose Ester & Cellulose Acetate (MCE & CA) (2020-2028) ($MN)
18 Global Tangential Flow Filtration Market Outlook, By Regenerated Cellulose (2020-2028) ($MN)
19 Global Tangential Flow Filtration Market Outlook, By Other Membrane Materials (2020-2028) ($MN)
20 Global Tangential Flow Filtration Market Outlook, By Technique (2020-2028) ($MN)
21 Global Tangential Flow Filtration Market Outlook, By Nanofiltration (2020-2028) ($MN)
22 Global Tangential Flow Filtration Market Outlook, By Microfiltration (2020-2028) ($MN)
23 Global Tangential Flow Filtration Market Outlook, By Ultrafiltration (2020-2028) ($MN)
24 Global Tangential Flow Filtration Market Outlook, By Other Techniques (2020-2028) ($MN)
25 Global Tangential Flow Filtration Market Outlook, By Application (2020-2028) ($MN)
26 Global Tangential Flow Filtration Market Outlook, By Raw Material Filtration (2020-2028) ($MN)
27 Global Tangential Flow Filtration Market Outlook, By Media Buffer Filtration (2020-2028) ($MN)
28 Global Tangential Flow Filtration Market Outlook, By Prefiltration (2020-2028) ($MN)
29 Global Tangential Flow Filtration Market Outlook, By Bioburden Testing (2020-2028) ($MN)
30 Global Tangential Flow Filtration Market Outlook, By Final Product Processing (2020-2028) ($MN)
31 Global Tangential Flow Filtration Market Outlook, By Active Pharmaceutical Ingredient (API) Filtration (2020-2028) ($MN)
32 Global Tangential Flow Filtration Market Outlook, By Protein Purification (2020-2028) ($MN)
33 Global Tangential Flow Filtration Market Outlook, By Vaccine and Antibody Processing (2020-2028) ($MN)
34 Global Tangential Flow Filtration Market Outlook, By Formulation and Filling Solutions (2020-2028) ($MN)
35 Global Tangential Flow Filtration Market Outlook, By Viral Clearance (2020-2028) ($MN)
36 Global Tangential Flow Filtration Market Outlook, By Cell Separation (2020-2028) ($MN)
37 Global Tangential Flow Filtration Market Outlook, By Water Purification (2020-2028) ($MN)
38 Global Tangential Flow Filtration Market Outlook, By Air Purification (2020-2028) ($MN)
39 Global Tangential Flow Filtration Market Outlook, By Other Applications (2020-2028) ($MN)
40 Global Tangential Flow Filtration Market Outlook, By End User (2020-2028) ($MN)
41 Global Tangential Flow Filtration Market Outlook, By Academic Institutes & Research Laboratories (2020-2028) ($MN)
42 Global Tangential Flow Filtration Market Outlook, By Pharmaceutical & Biotechnology Companies (2020-2028) ($MN)
43 Global Tangential Flow Filtration Market Outlook, By Contract Manufacturing Organisations (CMOs) & Contract Research Organisations (CROs) (2020-2028) ($MN)
44 Global Tangential Flow Filtration Market Outlook, By Other End Users (2020-2028) ($MN)

Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
 

List of Figures

RESEARCH METHODOLOGY


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.


Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.


For more details about research methodology, kindly write to us at info@strategymrc.com

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