Vaccine Adjuvants Market Forecasts to 2028 – Global Analysis By Type (Virus-like Particles, Tensoactive Adjuvants, Organic Adjuvants), Product (Adjuvant Emulsions, Combination Adjuvants), Disease Type (Cancer, Infectious Diseases) and By Geography
According to Stratistics MRC, the Global Vaccine Adjuvants Market is accounted for $791.00 million in 2021 and is expected to reach $2,040.87 million by 2028 growing at a CAGR of 14.5% during the forecast period. Adjuvants are fundamentally compounds that improve the body’s immunogenic reaction against antigens. As a result, these are majorly added to vaccines to increase their capability to influence long-term protection and safety against any kind of viruses. Currently, MF59 and aluminum salts are the only adjuvants which are viable for human usage. There have been a lot of developments done on the antigen discovery over the past decade which has enhanced the vaccine development process.
Rising Incidence of Naïve Infectious Chronic Diseases
The upsurge in the prevalence of cervical cancer, infectious diseases like Human Papillomavirus (HPV), HIV, tuberculosis, etc., and other fatal diseases are predicted to drive the market. Moreover, in recent years there has been an increasing focus on developing more efficient and longer-lasting vaccination against current and new diseases. The current onset of the Covid-19 pandemic is expected to create massive growth opportunities for the development of the global market. The research and development activities for creating a vaccine for Covid-19 have been underway at full force. With over a million cases across the globe and more than 160 countries affected, it has become imperative to find a vaccine for the infection. This will present a promising demand for the overall development of the market.
High Cost of Raw material
The increasing costs of the raw materials which in turn have lifted the cost of manufacturing are a few of the factors hindering the growth of the market. The cost of developing new vaccine adjuvants, the high toxicity of adjuvants on application, huge investment required for developing a new adjuvant, and strict regulatory requirements are some restraining factors that are expected to hamper the global vaccine adjuvants market growth.
Increasing Research & Development
Increased levels of spending and funding allocated for the development of more efficient vaccine adjuvants. The regional segment of Western Europe and the APEJ segment is next in line after North America in terms of revenue generation. Increasing government initiatives for vaccinations and the high prevalence of infectious & zoonotic diseases are accelerating the growth of the market. An increasing technological advancement focusing on improved & long-lasting vaccines for existing and emerging chronic diseases is creating ample opportunity for the market.
Adjuvanted vaccines can cause more local reactions (such as redness, swelling, and pain at the injection site) and more systemic reactions (such as fever, chills, and body aches) than non-adjuvanted vaccines. Side effects of adjuvants will further derail the market growth rate. The high manufacturing cost of these drugs will also create hindrances to the growth of this market.
Particulate Adjuvants segment is expected to be the largest during the forecast period
The Particulate segment is expected to hold the largest market share while adjuvant emulsion segment is predicted to grow with the highest CAGR. The factors can be attributed to the growing prevalence of diseases such as allergy, cancer, & HIV/AIDS, development of improved vaccine immunization, and rising demand for advanced treatment options.
The Intramuscular Route segment is expected to have the highest CAGR during the forecast period
The intramuscular Route segment is driven by owing to rapidly rising geriatric population and vaccines for enhanced immunization are propelling the growth of this segment. These include vaccines for HPV, influenza, meningitis, etc.
Region with highest share:
The Asia Pacific is projected to hold the highest market share. The growth in this market cantered at China and India. Increasing incidence of infectious diseases, rising number of conferences and symposiums, and high growth in the Indian biotechnology sector are the major factors driving the market in the Asian province. Moreover, the continuously improving healthcare facilities such as the availability of medicines, coupled with the increase in research & development funding to meet the huge unmet demands. This is expected to increase the market share over the forecast period.
Region with highest CAGR:
North America is projected to have the highest CAGR, owing to high adoption of the innovative products and incidence of major market players in this province especially in the United States. Further, favourable government support towards the growth of healthcare infrastructure is also contributing the growth of the vaccine adjuvants market in this region.
Key players in the market:
Some of the key players profiled in the Vaccine Adjuvants Market include Adjuvance Technologies, Inc, Adjuvatis, Agenus, Inc, Aphios Corp, Avanti Polar Lipids, CSL Limited, CureVac AG, GSK, Invivogen, Kineta, Inc, MVP Laboratories, Inc, Novartis/CSL, Novavax, Inc, OZ Biosciences, Sergeant Adjuvants, Sigma Aldrich (Merck KGaA), Vaxine Pty Ltd, Vaxliant, Viscogel AB, Sanofi, SK bioscience.
In February 2022: Sanofi and GSK intends to submit data from both their booster and Phase 3 efficacy trials as the basis for regulatory applications for a COVID-19 vaccine.
In August 2021: SK bioscience and GlaxoSmithKline plc (GSK) initiated a Phase 3 clinical study of SK’s COVID-19 vaccine candidate, GBP510, in combination with GSK’s pandemic adjuvant following positive interim Phase 1/2 results..
• Virus-like Particles
• Tensoactive Adjuvants
• Organic Adjuvants
• Mineral Salt based Adjuvants
• Carbohydrates Adjuvants
• Bacteria-derived Adjuvants
• Adjuvant Emulsions
• Combination Adjuvants
• Particulate Adjuvants
• Pathogen Components
Disease Types Covered:
• Infectious Diseases
Mechanism of Actions Covered:
• Vehicle Adjuvants
• Active Immunostimulants
Route of Administrations Covered:
• Subcutaneous Route
• Oral Route
• Intranasal Route
• Intramuscular Route
• Intradermal Route
• Veterinary Vaccine Adjuvants
• Human Vaccine Adjuvants
End Users Covered:
• Research Institutes
• Pharmaceutical Companies
• Contract Manufacturing Organization
• North America
o Rest of Europe
• Asia Pacific
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o South Africa
o Rest of Middle East & Africa
What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025 and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements
Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances
1 Executive Summary
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
3 Market Trend Analysis
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Vaccine Adjuvants Market, By Type
5.2 Virus-like Particles
5.3 Tensoactive Adjuvants
5.4 Organic Adjuvants
5.5 Mineral Salt based Adjuvants
5.8 Carbohydrates Adjuvants
5.9 Bacteria-derived Adjuvants
6 Global Vaccine Adjuvants Market, By Product
6.2 Adjuvant Emulsions
6.3 Combination Adjuvants
6.4 Particulate Adjuvants
6.5 Pathogen Components
7 Global Vaccine Adjuvants Market, By Disease Type
7.3 Infectious Diseases
8 Global Vaccine Adjuvants Market, By Mechanism of Action
8.2 Vehicle Adjuvants
8.4 Active Immunostimulants
9 Global Vaccine Adjuvants Market, By Route of Administration
9.2 Subcutaneous Route
9.3 Oral Route
9.4 Intranasal Route
9.5 Intramuscular Route
9.6 Intradermal Route
10 Global Vaccine Adjuvants Market, By Application
10.2 Veterinary Vaccine Adjuvants
10.3 Human Vaccine Adjuvants
11 Global Vaccine Adjuvants Market, By End User
11.2 Research Institutes
11.3 Pharmaceutical Companies
11.4 Contract Manufacturing Organization
12 Global Vaccine Adjuvants Market, By Geography
12.2 North America
12.3.6 Rest of Europe
12.4 Asia Pacific
12.4.5 New Zealand
12.4.6 South Korea
12.4.7 Rest of Asia Pacific
12.5 South America
12.5.4 Rest of South America
12.6 Middle East & Africa
12.6.1 Saudi Arabia
12.6.4 South Africa
12.6.5 Rest of Middle East & Africa
13 Key Developments
13.1 Agreements, Partnerships, Collaborations and Joint Ventures
13.2 Acquisitions & Mergers
13.3 New Product Launch
13.5 Other Key Strategies
14 Company Profiling
14.1 Adjuvance Technologies, Inc
14.3 Agenus, Inc.
14.4 Aphios Corp.
14.5 Avanti Polar Lipids
14.6 CSL Limited
14.7 CureVac AG
14.10 Kineta, Inc.
14.11 MVP Laboratories, Inc.
14.13 Novavax, Inc.
14.14 OZ Biosciences
14.15 Sergeant Adjuvants
14.16 Sigma Aldrich (Merck KGaA)
14.17 Vaxine Pty Ltd.
14.19 Viscogel AB
14.21 SK bioscience
List of Tables
1 Global Vaccine Adjuvants Market Outlook, By Region (2020-2028) (US $MN)
2 Global Vaccine Adjuvants Market Outlook, By Type (2020-2028) (US $MN)
3 Global Vaccine Adjuvants Market Outlook, By Virus-like Particles (2020-2028) (US $MN)
4 Global Vaccine Adjuvants Market Outlook, By Tensoactive Adjuvants (2020-2028) (US $MN)
5 Global Vaccine Adjuvants Market Outlook, By Organic Adjuvants (2020-2028) (US $MN)
6 Global Vaccine Adjuvants Market Outlook, By Mineral Salt based Adjuvants (2020-2028) (US $MN)
8 Global Vaccine Adjuvants Market Outlook, By Liposomesm(2020-2028) (US $MN)
9 Global Vaccine Adjuvants Market Outlook, By Emulsions (2020-2028) (US $MN)
10 Global Vaccine Adjuvants Market Outlook, By Carbohydrates Adjuvants (2020-2028) (US $MN)
11 Global Vaccine Adjuvants Market Outlook, By Bacteria-derived Adjuvants (2020-2028) (US $MN)
12 Global Vaccine Adjuvants Market Outlook, By Product (2020-2028) (US $MN)
13 Global Vaccine Adjuvants Market Outlook, By Adjuvant Emulsions (2020-2028) (US $MN)
14 Global Vaccine Adjuvants Market Outlook, By Combination Adjuvants (2020-2028) (US $MN)
15 Global Vaccine Adjuvants Market Outlook, By Particulate Adjuvants (2020-2028) (US $MN)
16 Global Vaccine Adjuvants Market Outlook, By Pathogen Components (2020-2028) (US $MN)
17 Global Vaccine Adjuvants Market Outlook, By Saponin (2020-2028) (US $MN)
18 Global Vaccine Adjuvants Market Outlook, By Disease Type (2020-2028) (US $MN)
19 Global Vaccine Adjuvants Market Outlook, By Cancer (2020-2028) (US $MN)
20 Global Vaccine Adjuvants Market Outlook, By Infectious Diseases (2020-2028) (US $MN)
21 Global Vaccine Adjuvants Market Outlook, By Mechanism of Action (2020-2028) (US $MN)
22 Global Vaccine Adjuvants Market Outlook, By Vehicle Adjuvants (2020-2028) (US $MN)
23 Global Vaccine Adjuvants Market Outlook, By Carriers (2020-2028) (US $MN)
24 Global Vaccine Adjuvants Market Outlook, By Active Immunostimulants (2020-2028) (US $MN)
25 Global Vaccine Adjuvants Market Outlook, By Route of Administration (2020-2028) (US $MN)
26 Global Vaccine Adjuvants Market Outlook, By Subcutaneous Route (2020-2028) (US $MN)
27 Global Vaccine Adjuvants Market Outlook, By Oral Route (2020-2028) (US $MN)
28 Global Vaccine Adjuvants Market Outlook, By Intranasal Route (2020-2028) (US $MN)
29 Global Vaccine Adjuvants Market Outlook, By Intramuscular Route (2020-2028) (US $MN)
30 Global Vaccine Adjuvants Market Outlook, By Intradermal Route (2020-2028) (US $MN)
31 Global Vaccine Adjuvants Market Outlook, By Application (2020-2028) (US $MN)
32 Global Vaccine Adjuvants Market Outlook, By Veterinary Vaccine Adjuvants (2020-2028) (US $MN)
33 Global Vaccine Adjuvants Market Outlook, By Human Vaccine Adjuvants (2020-2028) (US $MN)
34 Global Vaccine Adjuvants Market Outlook, By End User (2020-2028) (US $MN)
35 Global Vaccine Adjuvants Market Outlook, By Research Institutes (2020-2028) (US $MN)
36 Global Vaccine Adjuvants Market Outlook, By Pharmaceutical Companies (2020-2028) (US $MN)
37 Global Vaccine Adjuvants Market Outlook, By Contract Manufacturing Organization (2020-2028) (US $MN)
38 Global Vaccine Adjuvants Market Outlook, By Commercial (2020-2028) (US $MN)
39 Global Vaccine Adjuvants Market Outlook, By Pediatric (2020-2028) (US $MN)
40 Global Vaccine Adjuvants Market Outlook, By Adults (2020-2028) (US $MN)
Note- Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
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