Vaccine Adjuvants Market

Vaccine Adjuvants Market

Vaccine Adjuvants Market Forecasts to 2028 – Global Analysis By Type (Virus-like Particles, Tensoactive Adjuvants, Organic Adjuvants), Product (Adjuvant Emulsions, Combination Adjuvants), Disease Type (Cancer, Infectious Diseases) and By Geography

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Published: 2022 ID: SMRC21403

This report covers the impact of COVID-19 on this global market

Years Covered


Estimated Year Value (2021)

US $791.00 MN

Projected Year Value (2028)

US $2,040.87 MN

CAGR (2021 - 2028)


Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

Asia Pacific

Highest Growing Market

North America

According to Stratistics MRC, the Global Vaccine Adjuvants Market is accounted for $791.00 million in 2021 and is expected to reach $2,040.87 million by 2028 growing at a CAGR of 14.5% during the forecast period. Adjuvants are fundamentally compounds that improve the body’s immunogenic reaction against antigens. As a result, these are majorly added to vaccines to increase their capability to influence long-term protection and safety against any kind of viruses. Currently, MF59 and aluminum salts are the only adjuvants which are viable for human usage. There have been a lot of developments done on the antigen discovery over the past decade which has enhanced the vaccine development process.

Market Dynamics:


Rising Incidence of Naïve Infectious Chronic Diseases

The upsurge in the prevalence of cervical cancer, infectious diseases like Human Papillomavirus (HPV), HIV, tuberculosis, etc., and other fatal diseases are predicted to drive the market. Moreover, in recent years there has been an increasing focus on developing more efficient and longer-lasting vaccination against current and new diseases. The current onset of the Covid-19 pandemic is expected to create massive growth opportunities for the development of the global market. The research and development activities for creating a vaccine for Covid-19 have been underway at full force. With over a million cases across the globe and more than 160 countries affected, it has become imperative to find a vaccine for the infection. This will present a promising demand for the overall development of the market.


High Cost of Raw material 

The increasing costs of the raw materials which in turn have lifted the cost of manufacturing are a few of the factors hindering the growth of the market. The cost of developing new vaccine adjuvants, the high toxicity of adjuvants on application, huge investment required for developing a new adjuvant, and strict regulatory requirements are some restraining factors that are expected to hamper the global vaccine adjuvants market growth.


Increasing Research & Development

Increased levels of spending and funding allocated for the development of more efficient vaccine adjuvants. The regional segment of Western Europe and the APEJ segment is next in line after North America in terms of revenue generation. Increasing government initiatives for vaccinations and the high prevalence of infectious & zoonotic diseases are accelerating the growth of the market. An increasing technological advancement focusing on improved & long-lasting vaccines for existing and emerging chronic diseases is creating ample opportunity for the market.


Side Effects

Adjuvanted vaccines can cause more local reactions (such as redness, swelling, and pain at the injection site) and more systemic reactions (such as fever, chills, and body aches) than non-adjuvanted vaccines. Side effects of adjuvants will further derail the market growth rate. The high manufacturing cost of these drugs will also create hindrances to the growth of this market.

Particulate Adjuvants segment is expected to be the largest during the forecast period

The Particulate segment is expected to hold the largest market share while adjuvant emulsion segment is predicted to grow with the highest CAGR. The factors can be attributed to the growing prevalence of diseases such as allergy, cancer, & HIV/AIDS, development of improved vaccine immunization, and rising demand for advanced treatment options.

The Intramuscular Route segment is expected to have the highest CAGR during the forecast period

The intramuscular Route segment is driven by owing to rapidly rising geriatric population and vaccines for enhanced immunization are propelling the growth of this segment. These include vaccines for HPV, influenza, meningitis, etc.

Region with highest share:

The Asia Pacific is projected to hold the highest market share. The growth in this market cantered at China and India. Increasing incidence of infectious diseases, rising number of conferences and symposiums, and high growth in the Indian biotechnology sector are the major factors driving the market in the Asian province. Moreover, the continuously improving healthcare facilities such as the availability of medicines, coupled with the increase in research & development funding to meet the huge unmet demands. This is expected to increase the market share over the forecast period.

Region with highest CAGR:

North America is projected to have the highest CAGR, owing to high adoption of the innovative products and incidence of major market players in this province especially in the United States. Further, favourable government support towards the growth of healthcare infrastructure is also contributing the growth of the vaccine adjuvants market in this region.

Key players in the market:

Some of the key players profiled in the Vaccine Adjuvants Market include Adjuvance Technologies, Inc, Adjuvatis, Agenus, Inc, Aphios Corp, Avanti Polar Lipids, CSL Limited, CureVac AG, GSK, Invivogen, Kineta, Inc, MVP Laboratories, Inc, Novartis/CSL, Novavax, Inc, OZ Biosciences, Sergeant Adjuvants, Sigma Aldrich (Merck KGaA), Vaxine Pty Ltd, Vaxliant, Viscogel AB, Sanofi, SK bioscience.

Key developments:

In February 2022: Sanofi and GSK intends to submit data from both their booster and Phase 3 efficacy trials as the basis for regulatory applications for a COVID-19 vaccine.

In August 2021: SK bioscience and GlaxoSmithKline plc (GSK) initiated a Phase 3 clinical study of SK’s COVID-19 vaccine candidate, GBP510, in combination with GSK’s pandemic adjuvant following positive interim Phase 1/2 results..

Types Covered: 
• Virus-like Particles   
• Tensoactive Adjuvants         
• Organic Adjuvants    
• Mineral Salt based Adjuvants      
• Liposomes                
• Emulsions             
• Carbohydrates Adjuvants           
• Bacteria-derived Adjuvants      

Products Covered:
• Adjuvant Emulsions    
• Combination Adjuvants    
• Particulate Adjuvants    
• Pathogen Components    
• Saponin     

Disease Types Covered:
• Cancer   
• Infectious Diseases  
Mechanism of Actions Covered:
• Vehicle Adjuvants    
• Carriers        
• Active Immunostimulants

Route of Administrations Covered:
• Subcutaneous Route    
• Oral Route    
• Intranasal Route    
• Intramuscular Route    
• Intradermal Route 
Applications Covered:
• Veterinary Vaccine Adjuvants   
• Human Vaccine Adjuvants
End Users Covered:
• Research Institutes   
• Pharmaceutical Companies   
• Contract Manufacturing Organization   
• Commercial    
• Pediatric   
• Adults       

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan       
o China       
o India       
o Australia 
o New Zealand
o South Korea
o Rest of Asia Pacific   
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025 and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary    
2 Preface     

 2.1 Abstract   
 2.2 Stake Holders   
 2.3 Research Scope   
 2.4 Research Methodology   
  2.4.1 Data Mining  
  2.4.2 Data Analysis  
  2.4.3 Data Validation  
  2.4.4 Research Approach  
 2.5 Research Sources   
  2.5.1 Primary Research Sources  
  2.5.2 Secondary Research Sources  
  2.5.3 Assumptions  
3 Market Trend Analysis    

 3.1 Introduction   
 3.2 Drivers   
 3.3 Restraints   
 3.4 Opportunities   
 3.5 Threats   
 3.6 Product Analysis   
 3.7 Application Analysis   
 3.8 End User Analysis   
 3.9 Emerging Markets   
 3.10 Impact of Covid-19   
4 Porters Five Force Analysis    

 4.1 Bargaining power of suppliers   
 4.2 Bargaining power of buyers   
 4.3 Threat of substitutes   
 4.4 Threat of new entrants   
 4.5 Competitive rivalry   
5 Global Vaccine Adjuvants Market, By Type    
 5.1 Introduction   
 5.2 Virus-like Particles       
 5.3 Tensoactive Adjuvants             
 5.4 Organic Adjuvants        
 5.5 Mineral Salt based Adjuvants          
 5.6 Liposomes                    
 5.7 Emulsions                 
 5.8 Carbohydrates Adjuvants               
 5.9 Bacteria-derived Adjuvants        
6 Global Vaccine Adjuvants Market, By Product    
 6.1 Introduction   
 6.2 Adjuvant Emulsions        
 6.3 Combination Adjuvants        
 6.4 Particulate Adjuvants        
 6.5 Pathogen Components        
 6.6 Saponin       
7 Global Vaccine Adjuvants Market, By Disease Type    
 7.1 Introduction   
 7.2 Cancer        
 7.3 Infectious Diseases       
8 Global Vaccine Adjuvants Market, By Mechanism of Action      
 8.1 Introduction   
 8.2 Vehicle Adjuvants        
 8.3 Carriers            
 8.4 Active Immunostimulants      
9 Global Vaccine Adjuvants Market, By Route of Administration    
 9.1 Introduction   
 9.2 Subcutaneous Route        
 9.3 Oral Route        
 9.4 Intranasal Route        
 9.5 Intramuscular Route        
 9.6 Intradermal Route        
10 Global Vaccine Adjuvants Market, By Application    
 10.1 Introduction   
 10.2 Veterinary Vaccine Adjuvants       
 10.3 Human Vaccine Adjuvants        
11 Global Vaccine Adjuvants Market, By End User    
 11.1 Introduction   
 11.2 Research Institutes       
 11.3 Pharmaceutical Companies       
 11.4 Contract Manufacturing Organization       
 11.5 Commercial        
 11.6 Pediatric       
 11.7 Adults       
12 Global Vaccine Adjuvants Market, By Geography    
 12.1 Introduction   
 12.2 North America    
  12.2.1 US  
  12.2.2 Canada  
  12.2.3 Mexico  
 12.3 Europe   
  12.3.1 Germany  
  12.3.2 UK  
  12.3.3 Italy  
  12.3.4 France  
  12.3.5 Spain  
  12.3.6 Rest of Europe  
 12.4 Asia Pacific   
  12.4.1 Japan  
  12.4.2 China  
  12.4.3 India  
  12.4.4 Australia  
  12.4.5 New Zealand  
  12.4.6 South Korea  
  12.4.7 Rest of Asia Pacific  
 12.5 South America   
  12.5.1 Argentina  
  12.5.2 Brazil  
  12.5.3 Chile  
  12.5.4 Rest of South America  
 12.6 Middle East & Africa   
  12.6.1 Saudi Arabia  
  12.6.2 UAE  
  12.6.3 Qatar  
  12.6.4 South Africa  
  12.6.5 Rest of Middle East & Africa  
13 Key Developments    
 13.1 Agreements, Partnerships, Collaborations and Joint Ventures   
 13.2 Acquisitions & Mergers   
 13.3 New Product Launch   
 13.4 Expansions   
 13.5 Other Key Strategies   
14 Company Profiling    

 14.1 Adjuvance Technologies, Inc       
 14.2 Adjuvatis       
 14.3 Agenus, Inc.       
 14.4 Aphios Corp.       
 14.5 Avanti Polar Lipids       
 14.6 CSL Limited       
 14.7 CureVac AG       
 14.8 GSK       
 14.9 Invivogen       
 14.10 Kineta, Inc.       
 14.11 MVP Laboratories, Inc.       
 14.12 Novartis/CSL       
 14.13 Novavax, Inc.       
 14.14 OZ Biosciences       
 14.15 Sergeant Adjuvants       
 14.16 Sigma Aldrich (Merck KGaA)       
 14.17 Vaxine Pty Ltd.       
 14.18 Vaxliant       
 14.19 Viscogel AB       
 14.20 Sanofi    
 14.21 SK bioscience    

List of Tables     
1 Global Vaccine Adjuvants Market Outlook, By Region (2020-2028) (US $MN)     
2 Global Vaccine Adjuvants Market Outlook, By Type (2020-2028) (US $MN)     
3 Global Vaccine Adjuvants Market Outlook, By Virus-like Particles (2020-2028) (US $MN)     
4 Global Vaccine Adjuvants Market Outlook, By Tensoactive Adjuvants (2020-2028) (US $MN)     
5 Global Vaccine Adjuvants Market Outlook, By Organic Adjuvants (2020-2028) (US $MN)     
6 Global Vaccine Adjuvants Market Outlook, By Mineral Salt based Adjuvants (2020-2028) (US $MN)     
8 Global Vaccine Adjuvants Market Outlook, By Liposomesm(2020-2028) (US $MN)     
9 Global Vaccine Adjuvants Market Outlook, By Emulsions (2020-2028) (US $MN)     
10 Global Vaccine Adjuvants Market Outlook, By Carbohydrates Adjuvants (2020-2028) (US $MN)     
11 Global Vaccine Adjuvants Market Outlook, By Bacteria-derived Adjuvants (2020-2028) (US $MN)     
12 Global Vaccine Adjuvants Market Outlook, By Product (2020-2028) (US $MN)     
13 Global Vaccine Adjuvants Market Outlook, By Adjuvant Emulsions (2020-2028) (US $MN)     
14 Global Vaccine Adjuvants Market Outlook, By Combination Adjuvants (2020-2028) (US $MN)     
15 Global Vaccine Adjuvants Market Outlook, By Particulate Adjuvants (2020-2028) (US $MN)     
16 Global Vaccine Adjuvants Market Outlook, By Pathogen Components (2020-2028) (US $MN)     
17 Global Vaccine Adjuvants Market Outlook, By Saponin (2020-2028) (US $MN)     
18 Global Vaccine Adjuvants Market Outlook, By Disease Type (2020-2028) (US $MN)     
19 Global Vaccine Adjuvants Market Outlook, By Cancer (2020-2028) (US $MN)     
20 Global Vaccine Adjuvants Market Outlook, By Infectious Diseases (2020-2028) (US $MN)     
21 Global Vaccine Adjuvants Market Outlook, By Mechanism of Action (2020-2028) (US $MN)     
22 Global Vaccine Adjuvants Market Outlook, By Vehicle Adjuvants (2020-2028) (US $MN)     
23 Global Vaccine Adjuvants Market Outlook, By Carriers (2020-2028) (US $MN)     
24 Global Vaccine Adjuvants Market Outlook, By Active Immunostimulants (2020-2028) (US $MN)     
25 Global Vaccine Adjuvants Market Outlook, By Route of Administration (2020-2028) (US $MN)     
26 Global Vaccine Adjuvants Market Outlook, By Subcutaneous Route (2020-2028) (US $MN)     
27 Global Vaccine Adjuvants Market Outlook, By Oral Route (2020-2028) (US $MN)     
28 Global Vaccine Adjuvants Market Outlook, By Intranasal Route (2020-2028) (US $MN)     
29 Global Vaccine Adjuvants Market Outlook, By Intramuscular Route (2020-2028) (US $MN)     
30 Global Vaccine Adjuvants Market Outlook, By Intradermal Route      (2020-2028) (US $MN)     
31 Global Vaccine Adjuvants Market Outlook, By Application (2020-2028) (US $MN)     
32 Global Vaccine Adjuvants Market Outlook, By Veterinary Vaccine Adjuvants (2020-2028) (US $MN)     
33 Global Vaccine Adjuvants Market Outlook, By Human Vaccine Adjuvants (2020-2028) (US $MN)     
34 Global Vaccine Adjuvants Market Outlook, By End User (2020-2028) (US $MN)     
35 Global Vaccine Adjuvants Market Outlook, By Research Institutes (2020-2028) (US $MN)     
36 Global Vaccine Adjuvants Market Outlook, By Pharmaceutical Companies (2020-2028) (US $MN)     
37 Global Vaccine Adjuvants Market Outlook, By Contract Manufacturing Organization (2020-2028) (US $MN)     
38 Global Vaccine Adjuvants Market Outlook, By Commercial (2020-2028) (US $MN)     
39 Global Vaccine Adjuvants Market Outlook, By Pediatric (2020-2028) (US $MN)     
40 Global Vaccine Adjuvants Market Outlook, By Adults (2020-2028) (US $MN)     
Note- Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.    

List of Figures


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.

Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.

For more details about research methodology, kindly write to us at

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