Viscosupplementation Market
PUBLISHED: 2025 ID: SMRC28535
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Viscosupplementation Market

Viscosupplementation Market Forecasts to 2030 - Global Analysis By Product Type (Hyaluronic Acid (HA) Injections, Non-Hyaluronic Acid Products and Other Product Types), Source, Distribution Channel, Application and By Geography

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4.2 (52 reviews)
Published: 2025 ID: SMRC28535

This report covers the impact of COVID-19 on this global market
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According to Stratistics MRC, the Global Viscosupplementation Market is accounted for $5.4 billion in 2024 and is expected to reach $10.5 billion by 2030 growing at a CAGR of 11.5% during the forecast period. Viscosupplementation is a medical treatment for osteoarthritis (OA), primarily in the knee that involves injecting a gel-like substance, typically hyaluronic acid (HA), into the affected joint to supplement the natural synovial fluid. HA helps reduce pain and improve mobility by restoring the fluid's lubricating properties. This treatment is often used when conservative measures like pain medications or physical therapy have not provided sufficient relief. The procedure is minimally invasive, requiring just a few injections spaced over several weeks. 

According to an article published by the Centers for Disease Control and Prevention in April 2020, titled ""Osteoarthritis"", about 32.5 million people in the United States are suffering from osteoarthritis. In addition to this, 62% of women suffer from osteoarthritis.

Market Dynamics: 

Driver: 

Rising incidence of osteoarthritis

Osteoarthritis is becoming more prevalent, especially in weight-bearing joints like the knee. The increasing number of people suffering from this condition is creating a growing demand for effective treatment options. Viscosupplementation, offering a non-invasive alternative to surgery, has gained popularity as an option to alleviate symptoms and improve joint mobility. With osteoarthritis affecting millions, the need for reliable therapies, such as viscosupplementation, will continue to expand during the forecast period.

Restraint:

Lack of reimbursement policies

The high cost of the treatment and limited insurance coverage can hinder patient access to viscosupplementation injections. The absence of comprehensive reimbursement options may deter patients from opting for the procedure, especially in areas with stricter healthcare policies. This cost-related barrier can slow the widespread adoption of viscosupplementation as a treatment for osteoarthritis. Overcoming these reimbursement challenges will be crucial to ensuring broader market penetration.

Opportunity:

Increasing adoption of minimally invasive procedures

As patients and healthcare providers prioritize less invasive treatment options with quicker recovery times, viscosupplementation offers a compelling alternative to traditional surgical interventions. The procedure’s non-invasive nature, coupled with its potential to reduce pain and improve mobility, positions it as a favorable choice for managing osteoarthritis. With the growing trend toward outpatient, minimally invasive procedures, viscosupplementation is expected to gain further traction, expanding its market share. 

Threat:

Potential for adverse reactions

Viscosupplementation procedure can lead to side effects such as joint pain, swelling, or infection. The risk of these reactions may discourage some patients from choosing viscosupplementation as a treatment option. Additionally, adverse reactions, if not properly managed, could negatively impact the reputation of the treatment, creating hesitancy among both patients and healthcare providers. Addressing safety concerns and improving patient education is essential for minimizing this threat.

Covid-19 Impact

The Covid-19 pandemic had a mixed impact on the viscosupplementation market. On one hand, lockdowns and healthcare resource reallocations slowed elective procedures, including viscosupplementation injections, due to restricted access to clinics. On the other hand, the pandemic highlighted the importance of non-surgical treatments for managing chronic conditions like osteoarthritis, leading to a rebound in demand as healthcare systems adapted. With a growing focus on reducing hospital visits and promoting outpatient care, viscosupplementation may see sustained growth as a preferred treatment in the post-pandemic era.

The hyaluronic acid (HA) injections segment is expected to be the largest during the forecast period

The hyaluronic acid (HA) injections segment is expected to account for the largest market share during the forecast period owing to its ability to restore synovial fluid, providing lubrication and reducing inflammation in osteoarthritis -affected joints. Its proven effectiveness and long-standing use in viscosupplementation have made it the preferred choice for both patients and healthcare providers. As the most established and widely used form of viscosupplementation, the HA injections segment is anticipated to dominate the market in the coming years. 

The non-animal source segment is expected to have the highest CAGR during the forecast period

Over the forecast period, the non-animal source segment is predicted to witness the highest growth rate due to increasing concerns over the potential risks of animal-derived products, non-animal-based hyaluronic acid offers a more attractive option for patients. These products cater to individuals who may have allergies or ethical concerns related to animal-based treatments. The demand for non-animal sourced viscosupplementation products is rising as they are perceived to be safer and more sustainable, offering manufacturers a growing opportunity to expand their market reach and meet consumer preferences.

Region with largest share:

During the forecast period, the North America region is expected to hold the largest market share owing to high awareness of osteoarthritis treatments, and significant healthcare spending. With a strong preference for non-invasive treatments like viscosupplementation, North America’s large aging population will drive continued demand. Furthermore, the presence of leading manufacturers and research institutions in the United States and Canada will support innovation and the growth of the viscosupplementation market throughout the forecast period.

Region with highest CAGR:

Over the forecast period, the Asia Pacific region is anticipated to exhibit the highest CAGR driven by rapid urbanization, increasing healthcare access, and a growing elderly population are contributing to the rising prevalence of osteoarthritis in this region. Countries like China, India, and Japan are seeing greater adoption of viscosupplementation due to rising healthcare awareness and improved medical facilities. 

Key players in the market

Some of the key players in Viscosupplementation market include Anika Therapeutics, Inc., Aptissen, Bioventus LLC, Chugai Pharmaceuticals Co., Ltd., DePuy Synthes, F.Hoffmann-La Roche Ltd., Ferring Pharmaceuticals B.V., Fidia Farmaceutici S.p.A, Johnson & Johnson Services, Inc., LG Life Sciences Ltd., Lifecore Biomedical, OrthogenRx Inc., Sanofi, Seikagaku Corp., Smith & Nephew PLC and Zimmer Biomet. 

Key Developments:

In November 2024, Roche announced that it has entered into a definitive merger agreement to acquire Poseida Therapeutics, Inc. a public clinical-stage biopharmaceutical company pioneering donor-derived CAR-T cell therapies.

In December 2024, Smith+Nephew announced its CORIOGRAPH Pre-Op Planning and Modeling Services are now cleared for total hip arthroplasty (THA) by the United States Food and Drug Administration.

Product Types Covered:
• Hyaluronic Acid (HA) Injections
• Non-Hyaluronic Acid Products
• Other Product Types 

Sources Covered:
• Animal Source
• Non-Animal Source   

Distribution Channels Covered:
• Direct Sales 
• Clinics 
• Retail Pharmacies & Drugstores 
• Online Pharmacies & E-commerce Platforms 
• Other Distribution Channels  

Applications Covered:
• Osteoarthritis 
• Post-Traumatic Arthritis 
• Rheumatoid Arthritis 
• Knee Osteoarthritis 
• Other Applications  

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan        
o China        
o India        
o Australia  
o New Zealand
o South Korea
o Rest of Asia Pacific    
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa 
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2022, 2023, 2024, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings: 
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary       
         
2 Preface        
 2.1 Abstract       
 2.2 Stake Holders      
 2.3 Research Scope      
 2.4 Research Methodology     
  2.4.1 Data Mining     
  2.4.2 Data Analysis     
  2.4.3 Data Validation     
  2.4.4 Research Approach     
 2.5 Research Sources      
  2.5.1 Primary Research Sources    
  2.5.2 Secondary Research Sources    
  2.5.3 Assumptions     
         
3 Market Trend Analysis      
 3.1 Introduction      
 3.2 Drivers       
 3.3 Restraints      
 3.4 Opportunities      
 3.5 Threats       
 3.6 Product Analysis      
 3.7 Application Analysis     
 3.8 Emerging Markets      
 3.9 Impact of Covid-19      
         
4 Porters Five Force Analysis      
 4.1 Bargaining power of suppliers     
 4.2 Bargaining power of buyers     
 4.3 Threat of substitutes     
 4.4 Threat of new entrants     
 4.5 Competitive rivalry      
         
5 Global Viscosupplementation Market, By Product Type   
 5.1 Introduction      
 5.2 Hyaluronic Acid (HA) Injections    
  5.2.1 Single-Injection Products    
  5.2.2 Multiple-Injection Products    
  5.2.3 Five-Injection Products    
 5.3 Non-Hyaluronic Acid Products     
  5.3.1 Collagen-Based Injections    
  5.3.2 Platelet-Rich Plasma    
  5.3.3 Stem Cell-Based Injections    
 5.4 Other Product Types     
         
6 Global Viscosupplementation Market, By Source    
 6.1 Introduction      
 6.2 Animal Source      
 6.3 Non-Animal Source      
         
7 Global Viscosupplementation Market, By Distribution Channel  
 7.1 Introduction      
 7.2 Direct Sales      
 7.3 Clinics       
 7.4 Retail Pharmacies & Drugstores    
 7.5 Online Pharmacies & E-commerce Platforms   
 7.6 Other Distribution Channels     
         
8 Global Viscosupplementation Market, By Application   
 8.1 Introduction      
 8.2 Osteoarthritis      
 8.3 Post-Traumatic Arthritis     
 8.4 Rheumatoid Arthritis     
 8.5 Knee Osteoarthritis      
 8.6 Other Applications      
         
9 Global Viscosupplementation Market, By Geography   
 9.1 Introduction      
 9.2 North America      
  9.2.1 US      
  9.2.2 Canada      
  9.2.3 Mexico      
 9.3 Europe       
  9.3.1 Germany      
  9.3.2 UK      
  9.3.3 Italy      
  9.3.4 France      
  9.3.5 Spain      
  9.3.6 Rest of Europe     
 9.4 Asia Pacific      
  9.4.1 Japan      
  9.4.2 China      
  9.4.3 India      
  9.4.4 Australia      
  9.4.5 New Zealand     
  9.4.6 South Korea     
  9.4.7 Rest of Asia Pacific     
 9.5 South America      
  9.5.1 Argentina     
  9.5.2 Brazil      
  9.5.3 Chile      
  9.5.4 Rest of South America    
 9.6 Middle East & Africa     
  9.6.1 Saudi Arabia     
  9.6.2 UAE      
  9.6.3 Qatar      
  9.6.4 South Africa     
  9.6.5 Rest of Middle East & Africa    
         
10 Key Developments       
 10.1 Agreements, Partnerships, Collaborations and Joint Ventures  
 10.2 Acquisitions & Mergers     
 10.3 New Product Launch     
 10.4 Expansions      
 10.5 Other Key Strategies     
         
11 Company Profiling       
 11.1 Anika Therapeutics, Inc.     
 11.2 Aptissen       
 11.3 Bioventus LLC      
 11.4 Chugai Pharmaceuticals Co., Ltd.    
 11.5 DePuy Synthes      
 11.6 F.Hoffmann-La Roche Ltd.     
 11.7 Ferring Pharmaceuticals B.V.     
 11.8 Fidia Farmaceutici S.p.A     
 11.9 Johnson & Johnson Services, Inc.    
 11.10 LG Life Sciences Ltd.      
 11.11 Lifecore Biomedical      
 11.12 OrthogenRx Inc.      
 11.13 Sanofi       
 11.14 Seikagaku Corp.      
 11.15 Smith & Nephew PLC     
 11.16 Zimmer Biomet      
         
List of Tables        
1 Global Viscosupplementation Market Outlook, By Region (2022-2030) ($MN) 
2 Global Viscosupplementation Market Outlook, By Product Type (2022-2030) ($MN) 
3 Global Viscosupplementation Market Outlook, By Hyaluronic Acid (HA) Injections (2022-2030) ($MN)
4 Global Viscosupplementation Market Outlook, By Single-Injection Products (2022-2030) ($MN)
5 Global Viscosupplementation Market Outlook, By Multiple-Injection Products (2022-2030) ($MN)
6 Global Viscosupplementation Market Outlook, By Five-Injection Products (2022-2030) ($MN)
7 Global Viscosupplementation Market Outlook, By Non-Hyaluronic Acid Products (2022-2030) ($MN)
8 Global Viscosupplementation Market Outlook, By Collagen-Based Injections (2022-2030) ($MN)
9 Global Viscosupplementation Market Outlook, By Platelet-Rich Plasma (2022-2030) ($MN)
10 Global Viscosupplementation Market Outlook, By Stem Cell-Based Injections (2022-2030) ($MN)
11 Global Viscosupplementation Market Outlook, By Other Product Types (2022-2030) ($MN)
12 Global Viscosupplementation Market Outlook, By Source (2022-2030) ($MN) 
13 Global Viscosupplementation Market Outlook, By Animal Source (2022-2030) ($MN)
14 Global Viscosupplementation Market Outlook, By Non-Animal Source (2022-2030) ($MN)
15 Global Viscosupplementation Market Outlook, By Distribution Channel (2022-2030) ($MN)
16 Global Viscosupplementation Market Outlook, By Direct Sales (2022-2030) ($MN) 
17 Global Viscosupplementation Market Outlook, By Clinics (2022-2030) ($MN) 
18 Global Viscosupplementation Market Outlook, By Retail Pharmacies & Drugstores (2022-2030) ($MN)
19 Global Viscosupplementation Market Outlook, By Online Pharmacies & E-commerce Platforms (2022-2030) ($MN)
20 Global Viscosupplementation Market Outlook, By Other Distribution Channels (2022-2030) ($MN)
21 Global Viscosupplementation Market Outlook, By Application (2022-2030) ($MN) 
22 Global Viscosupplementation Market Outlook, By Osteoarthritis (2022-2030) ($MN)
23 Global Viscosupplementation Market Outlook, By Post-Traumatic Arthritis (2022-2030) ($MN)
24 Global Viscosupplementation Market Outlook, By Rheumatoid Arthritis (2022-2030) ($MN)
25 Global Viscosupplementation Market Outlook, By Knee Osteoarthritis (2022-2030) ($MN)
26 Global Viscosupplementation Market Outlook, By Other Applications (2022-2030) ($MN)
         
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures

RESEARCH METHODOLOGY


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.


Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.


For more details about research methodology, kindly write to us at info@strategymrc.com

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