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Blow Fill Seal Bfs Technology Market

Blow Fill Seal (BFS) Technology Market Forecasts to 2028 – Global Analysis By Type (Heat Sensitive, Oxygen Sensitive, Light Sensitive), Product (Inhalation, Parenterals), Capacity, Machine Type, Material, and By Geography

4.1 (86 reviews)
Published: March 2022 ID: SMRC20788
4.1 (86 reviews)
Published: March 2022 ID: SMRC20788

This report covers the impact of COVID-19 on this global market
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According to Stratistics MRC, the Global Blow Fill Seal (BFS) Technology Market is accounted for $355.38 million in 2021 and is expected to reach $617.00 million by 2028 growing at a CAGR of 8.2% during the forecast period. Blow-Fill-Seal technology is a technique used to manufacture liquid-filled polymer containers as small volume (0.1mL to 99mL) as well as large volume (100mL and above). The technology is developed in Europe and has significant demand in Europe followed by North America. The technique has relatively high use in the pharmaceutical market to fill the parental preparation with comparatively less intervention of human being. The technology is considered as a superior method for aseptic filling of parental preparation by various regulatory bodies such as the U.S. Food and Drug Administration (FDA). Blow-Fill-Seal (BFS) technology is used in filling of eye drops, infusions, inhalation, and other parental preparations.

Market Dynamics:

Driver:

Rising demand from end user industries


Most of the end user industries especially pharmaceutical manufacturers are using advanced sterilization technologies to minimize operator intervention and the risk of contamination in filling and packaging liquid parenteral drugs. Blow-fill-seal (BFS) technology provides various advantages, including flexibility in packaging design, low operating cost, assurance of high degree of sterility, limited space requirement, limited component inventory, and limited labor requirement, making it is a preferred technology for packaging drugs. The demand for advanced aseptic packaging, such as bottles, vials, pre-filled syringes, and ampoules using the blow-fill-seal (BFS) technology are increasing in the pharmaceutical sector. Advancements in BFS technology are enabling packaging of a wider variety of containers, such as vials with inserted tips/caps, twist-off & re-closeable vials, multi-dose use bottles, eyewash & contact lens solution bottles, unit dose Pre-filled syringes & injectable, and electrolyte & sports drinks bottles.

Restraint:

Pressure on pharmaceutical manufacturers to maintain affordable pricing


The constant pressure on pharmaceutical manufacturers to maintain affordable pricing of their products continues to perturb the industry. Patent losses and increasing government pressure to curb healthcare losses are key factors that are impacting the revenue of pharmaceutical companies. Patent expirations are further allowing the proliferation of the generic drugs market which is gradually expanding its reach at the expense of specialized drug manufacturers. Integration of blow fill seal technology incurs a heavy cost due to the requirement of skilled labor, straight line maintenance and depreciation, and resins. Although the blow fill seal technology offers a plethora of advantages, pharmaceutical manufacturers show signs of reluctance when integrating the blow fill seal technology to production lines. These factors could impede the growth of blow fill seal technology market.

Opportunity:

Growing inclination from aseptic packaging


Aseptic packaging using BFS technology provides high accuracy in terms of the number of uncontaminated products packed per minute. Blow fill seal technology provides a sterile solution, fulfilling the requirement for aseptic conditions by reducing human interference in the fill & finish process. BFS technology is automated using which containers are formed, filled, and sealed in one continuous operation. BFS technology is widely used for the aseptic packaging of respiratory, ophthalmic, oral, and Pre-filled syringes & injectable drugs. These products do not require refrigeration and are, therefore, convenient for consumers and cost-effective for distributors. BFS machinery is designed to prevent the potential for extraneous contamination, making it suitable for single dose (unit-dose) aseptic and sterilized drug products.
 
Threat:

Cost-to-benefit ratio


Blow Fill Seal (BFS) technology is a capital-intensive platform. The initial capital required to establish a BFS technology plant is huge. Advanced technologies and a regulated environment are required to pack products aseptically using BFS technology. Players with high-investment capabilities are entering the market, as high returns are received only in the long term. Thus, small manufacturers are reluctant to invest as they do not have the capital required for the high initial investments. This discourages manufacturers from investing in this technology and reduces the upstream demand in the BFS technology market.

The food & beverages segment is expected to be the largest during the forecast period

The food & beverages segment is estimated to have a lucrative growth. The demand for in-house packaging in the food and beverages industry is on the rise. Customized blow fill seal technology can streamline the packaging process for companies and could substantially enhance their profits by eliminating the need for warehousing of raw materials and simplifying the handling process. Blow fill seal technology is expected to find widespread adoption in the carbonated drinks packaging owing to its advanced leak proofing and sealing applications. The benefits of using blow fill seal technology in packaging are likely expected to reduce the time to market for food and beverages companies while lowering the consumption of raw material required in the process. F&B companies are growing increasingly aware of the benefits offered by the technology which, in turn, is likely to propel the growth of the blow fill seal technology market.

The prefilled syringes & injectable segment is expected to have the highest CAGR during the forecast period

The prefilled syringes & injectable segment is anticipated to witness the fastest CAGR growth during the forecast period.  The prefilled syringes & injectable are estimated to hold more than 65% of market share in the global market and increased by 400 bps of 2021’s market share. This growth was due to the demand for completely aseptic and efficient product. Prefilled syringes improve maintaining aseptic condition for treatment and drug intake. This growth is attributed to increasing demand for aseptic drug delivery to reduce impact of chronic diseases.

Region with highest share:

North America is projected to hold the largest market share during the forecast period. In North America, pharma & healthcare companies are using blow fill seal (BFS) technology extensively in order to fulfil the need for single-dose packaging. A higher demand for single-dose packaging in pharmaceutical industries is widespread in all the other parts of the world as well. With the increasing business activities of the U.S., the overall attractiveness of blow fill seal technology in this market is more and anticipated to create lucrative growth opportunities for the key players who are working with blow fill seal technology in future years.

Region with highest CAGR:

Asia Pacific is projected to have the highest CAGR over the forecast period owing to the factors such as the growing healthcare & pharmaceutical industry in China and India. High growth of supply chain activities to cater various industries and development of packaging solutions is key to the growth of blow fill seal technology market in this region. In addition to this development of cold chain systems to cater perishable goods and government regulations on packaging waste disposal is also governing the demand for blow fill seal technology market in this region. Major industries in these regions are estimated to be food & beverage, pharmaceutical, cosmetic & personal care, and others.

Key players in the market

Some of the key players profiled in the Blow Fill Seal (BFS) Technology Market include BioConnection, Birgi Mefar Group, Catalent, Curida, Gerresheimer, Lyondellbasell, Nupharma Group, Pharmapack, Recipharm, Salvat, The Ritedose Corporation, Unicep Packaging, Unipharma, Unither Pharmaceuticals, and Weiler Engineering.

Key Developments:

In March 2022, Gerresheimer ceremoniously took over a new building in Berlin, Ohio. In the future, the square plastic containers of the Duma Twist-Off Q brand with a 40-ml filling volume, child-resistant closure, and desiccant for filling with medications for the North American market will be produced here in a clean room.

In April 2019, Unicep Packaging LLC, a liquid filling and packaging company, announced the expansion of their services to include refined custom design and quick turn prototype capabilities. These services will be available with Unicep’s single-use modified blow fill seal technology product line.
 
Types Covered:
• Heat Sensitive
• Oxygen Sensitive
• Light Sensitive
 
Products Covered:
• Inhalation
• Parenteral
• Prefilled Syringes & Injectable
• Vial
• Drugs
• Bottle
• Ampoules
 
Capacities Covered:
• Small Volume (1mL-99mL)
• Large Volume (100mL and Above)
 
Machine Types Covered:
• Horizontal Form
• Vertical Form
 
Materials Covered:
• Polypropylene (PP)
• Polyethylene (PE)
• Polyvinylchloride (PVC)
• Multilayer
• Ethylene Vinyl Alcohol (EVOH)
 
Technologies Covered:
• Manual
• Semi-Automatic
• Fully Automatic
 
End Users Covered:

• Automotive
• Aerospace
• Chemical
• Cosmetic & Personal Care
• Food & Beverages
• Healthcare & Pharmaceuticals
• Energy & Power
• Electronics
• Agriculture

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan       
o China       
o India       
o Australia 
o New Zealand
o South Korea
o Rest of Asia Pacific   
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Key Questions Answered In The Report

The Global Blow Fill Seal (BFS) Technology Market is majorly driven by increasing demand from the pharmaceutical & healthcare industries, increasing demand from the aseptic packaging industry, and growth of the parent industry.

The semi- automatic segment is growing at a highest CAGR owing to the increasing demand for food & beverages and personal healthcare products around the world.

Asia Pacific dominated with a significant market share due to the growing healthcare & pharmaceutical industry in China and India.

North America market is growing at a highest CAGR due to growing pharmaceutical industry development and implementation of advanced technology for manufacturing new drugs discovery in the region.

Key players in Blow Fill Seal (BFS) Technology Market include BioConnection, Birgi Mefar Group, Catalent, Curida, Gerresheimer, Lyondellbasell, Nupharma Group, Pharmapack, Recipharm, Salvat, The Ritedose Corporation, Unicep Packaging, Unither Pharmaceuticals, and Weiler Engineering.

1 Executive Summary        
           
2 Preface         

 2.1 Abstract        
 2.2 Stake Holders       
 2.3 Research Scope       
 2.4 Research Methodology      
  2.4.1 Data Mining      
  2.4.2 Data Analysis      
  2.4.3 Data Validation      
  2.4.4 Research Approach       
 2.5 Research Sources       
  2.5.1 Primary Research Sources     
  2.5.2 Secondary Research Sources     
  2.5.3 Assumptions      
          
3 Market Trend Analysis       

 3.1 Introduction       
 3.2 Drivers        
 3.3 Restraints       
 3.4 Opportunities       
 3.5 Threats        
 3.6 Product Analysis       
 3.7 Technology Analysis      
 3.8 End User Analysis       
 3.9 Emerging Markets       
 3.10 Impact of Covid-19       
          
4 Porters Five Force Analysis       
 4.1 Bargaining power of suppliers      
 4.2 Bargaining power of buyers      
 4.3 Threat of substitutes      
 4.4 Threat of new entrants      
 4.5 Competitive rivalry       
          
5 Global Blow Fill Seal (BFS) Technology Market, By Type    
 5.1 Introduction       
 5.2 Heat Sensitive       
 5.3 Oxygen Sensitive       
 5.4 Light Sensitive       
          
6 Global Blow Fill Seal (BFS) Technology Market, By Product    

 6.1 Introduction       
 6.2 Inhalation       
 6.3 Parenterals       
 6.4 Prefilled Syringes & Injectables     
 6.5 Vial        
  6.5.1 0.1-10 ml       
  6.5.2 10-50 ml       
 6.6 Drugs        
 6.7 Bottle        
  6.7.1 0.2-100 ml      
  6.7.2 100-500 ml      
  6.7.3 Above 500 ml      
 6.8 Ampoules       
  6.8.1 Unit-Dose Ampoules     
  6.8.2 Multi-Dose Ampoules     
          
7 Global Blow Fill Seal (BFS) Technology Market, By Capacity    
 7.1 Introduction       
 7.2 Small Volume (1mL-99mL)      
 7.3 Large Volume (100mL and Above)      
          
8 Global Blow Fill Seal (BFS) Technology Market, By Machine Type   
 8.1 Introduction       
 8.2 Horizontal Form       
 8.3 Vertical Form       
          
9 Global Blow Fill Seal (BFS) Technology Market, By Material    
 9.1 Introduction       
 9.2 Polypropylene (PP)       
 9.3 Polyethylene (PE)       
  9.3.1 Low-Density Polyethylene (LDPE)    
  9.3.2 High-Density Polyethylene (HDPE)    
 9.4 Polyvinylchloride (PVC)      
 9.5 Multilayer       
 9.6 Ethylene Vinyl Alcohol (EVOH)     
          
10 Global Blow Fill Seal (BFS) Technology Market, By Technology    
 10.1 Introduction       
 10.2 Manual        
 10.3 Semi-Automatic       
 10.4 Fully Automatic       
          
11 Global Blow Fill Seal (BFS) Technology Market, By End User    
 11.1 Introduction       
 11.2 Automotive       
 11.3 Aerospace       
 11.4 Chemical        
 11.5 Cosmetic & Personal Care      
 11.6 Food & Beverages       
  11.6.1 Fruits       
  11.6.2 Vegetables      
 11.7 Healthcare & Pharmaceuticals      
  11.7.1 Respiratory      
  11.7.2 Biologics       
  11.7.3 Injectables      
  11.7.4 Medical Devices      
  11.7.5 Ophthalmic      
  11.7.6 Vaccine       
  11.7.7 Wound Care      
 11.8 Energy & Power       
 11.9 Electronics       
 11.10 Agriculture       
          
12 Global Blow Fill Seal (BFS) Technology Market, By Geography    
 12.1 Introduction       
 12.2 North America       
  12.2.1 US       
  12.2.2 Canada       
  12.2.3 Mexico       
 12.3 Europe        
  12.3.1 Germany       
  12.3.2 UK       
  12.3.3 Italy       
  12.3.4 France       
  12.3.5 Spain       
  12.3.6 Rest of Europe      
 12.4 Asia Pacific       
  12.4.1 Japan       
  12.4.2 China       
  12.4.3 India        
  12.4.4 Australia       
  12.4.5 New Zealand      
  12.4.6 South Korea      
  12.4.7 Rest of Asia Pacific      
 12.5 South America       
  12.5.1 Argentina      
  12.5.2 Brazil       
  12.5.3 Chile       
  12.5.4 Rest of South America     
 12.6 Middle East & Africa      
  12.6.1 Saudi Arabia      
  12.6.2 UAE       
  12.6.3 Qatar       
  12.6.4 South Africa      
  12.6.5 Rest of Middle East & Africa     
          
13 Key Developments        
 13.1 Agreements, Partnerships, Collaborations and Joint Ventures   
 13.2 Acquisitions & Mergers      
 13.3 New Product Launch      
 13.4 Expansions       
 13.5 Other Key Strategies      
          
14 Company Profiling        
 14.1 BioConnection       
 14.2 Birgi Mefar Group       
 14.3 Catalent        
 14.4 Curida        
 14.5 Gerresheimer       
 14.6 Lyondellbasell       
 14.7 Nupharma Group       
 14.8 Pharmapack       
 14.9 Recipharm       
 14.10 Salvat        
 14.11 The Ritedose Corporation       
 14.12 Unicep Packaging       
 14.13 Unipharma       
 14.14 Unither Pharmaceuticals      
 14.15 Weiler Engineering       


List of Tables         
1 Global Blow Fill Seal (BFS) Technology Market Outlook, By Region (2020-2028) ($MN) 
2 Global Blow Fill Seal (BFS) Technology Market Outlook, By Type (2020-2028) ($MN)  
3 Global Blow Fill Seal (BFS) Technology Market Outlook, By Heat Sensitive (2020-2028) ($MN) 
4 Global Blow Fill Seal (BFS) Technology Market Outlook, By Oxygen Sensitive (2020-2028) ($MN)
5 Global Blow Fill Seal (BFS) Technology Market Outlook, By Light Sensitive (2020-2028) ($MN) 
6 Global Blow Fill Seal (BFS) Technology Market Outlook, By Product (2020-2028) ($MN) 
7 Global Blow Fill Seal (BFS) Technology Market Outlook, By Inhalation (2020-2028) ($MN) 
8 Global Blow Fill Seal (BFS) Technology Market Outlook, By Parenterals (2020-2028) ($MN) 
9 Global Blow Fill Seal (BFS) Technology Market Outlook, By Prefilled Syringes & Injectables (2020-2028) ($MN)
10 Global Blow Fill Seal (BFS) Technology Market Outlook, By Vial (2020-2028) ($MN)  
11 Global Blow Fill Seal (BFS) Technology Market Outlook, By 0.1-10 ml (2020-2028) ($MN) 
12 Global Blow Fill Seal (BFS) Technology Market Outlook, By 10-50 ml (2020-2028) ($MN) 
13 Global Blow Fill Seal (BFS) Technology Market Outlook, By Drugs (2020-2028) ($MN) 
14 Global Blow Fill Seal (BFS) Technology Market Outlook, By Bottle (2020-2028) ($MN) 
15 Global Blow Fill Seal (BFS) Technology Market Outlook, By 0.2-100 ml (2020-2028) ($MN) 
16 Global Blow Fill Seal (BFS) Technology Market Outlook, By 100-500 ml (2020-2028) ($MN) 
17 Global Blow Fill Seal (BFS) Technology Market Outlook, By Above 500 ml (2020-2028) ($MN) 
18 Global Blow Fill Seal (BFS) Technology Market Outlook, By Ampoules (2020-2028) ($MN) 
19 Global Blow Fill Seal (BFS) Technology Market Outlook, By Unit-Dose Ampoules (2020-2028) ($MN)
20 Global Blow Fill Seal (BFS) Technology Market Outlook, By Multi-Dose Ampoules (2020-2028) ($MN)
21 Global Blow Fill Seal (BFS) Technology Market Outlook, By Capacity (2020-2028) ($MN) 
22 Global Blow Fill Seal (BFS) Technology Market Outlook, By Small Volume (1mL-99mL) (2020-2028) ($MN)
23 Global Blow Fill Seal (BFS) Technology Market Outlook, By Large Volume (100mL and Above) (2020-2028) ($MN)
24 Global Blow Fill Seal (BFS) Technology Market Outlook, By Machine Type  (2020-2028) ($MN) 
25 Global Blow Fill Seal (BFS) Technology Market Outlook, By Horizontal Form (2020-2028) ($MN)
26 Global Blow Fill Seal (BFS) Technology Market Outlook, By Vertical Form (2020-2028) ($MN) 
27 Global Blow Fill Seal (BFS) Technology Market Outlook, By Material (2020-2028) ($MN) 
28 Global Blow Fill Seal (BFS) Technology Market Outlook, By Polypropylene (PP) (2020-2028) ($MN)
29 Global Blow Fill Seal (BFS) Technology Market Outlook, By Polyethylene (PE) (2020-2028) ($MN)
30 Global Blow Fill Seal (BFS) Technology Market Outlook, By Low-Density Polyethylene (LDPE) (2020-2028) ($MN)
31 Global Blow Fill Seal (BFS) Technology Market Outlook, By High-Density Polyethylene (HDPE) (2020-2028) ($MN)
32 Global Blow Fill Seal (BFS) Technology Market Outlook, By Polyvinylchloride (PVC) (2020-2028) ($MN)
33 Global Blow Fill Seal (BFS) Technology Market Outlook, By Multilayer (2020-2028) ($MN) 
34 Global Blow Fill Seal (BFS) Technology Market Outlook, By Ethylene Vinyl Alcohol (EVOH) (2020-2028) ($MN)
35 Global Blow Fill Seal (BFS) Technology Market Outlook, By Technology (2020-2028) ($MN) 
36 Global Blow Fill Seal (BFS) Technology Market Outlook, By Manual (2020-2028) ($MN) 
37 Global Blow Fill Seal (BFS) Technology Market Outlook, By Semi-Automatic (2020-2028) ($MN)
38 Global Blow Fill Seal (BFS) Technology Market Outlook, By Fully Automatic (2020-2028) ($MN)
39 Global Blow Fill Seal (BFS) Technology Market Outlook, By End User (2020-2028) ($MN) 
40 Global Blow Fill Seal (BFS) Technology Market Outlook, By Automotive (2020-2028) ($MN) 
41 Global Blow Fill Seal (BFS) Technology Market Outlook, By Aerospace (2020-2028) ($MN) 
42 Global Blow Fill Seal (BFS) Technology Market Outlook, By Chemical (2020-2028) ($MN) 
43 Global Blow Fill Seal (BFS) Technology Market Outlook, By Cosmetic & Personal Care (2020-2028) ($MN)
44 Global Blow Fill Seal (BFS) Technology Market Outlook, By Food & Beverages (2020-2028) ($MN)
45 Global Blow Fill Seal (BFS) Technology Market Outlook, By Fruits (2020-2028) ($MN) 
46 Global Blow Fill Seal (BFS) Technology Market Outlook, By Vegetables (2020-2028) ($MN) 
47 Global Blow Fill Seal (BFS) Technology Market Outlook, By Healthcare & Pharmaceuticals (2020-2028) ($MN)
48 Global Blow Fill Seal (BFS) Technology Market Outlook, By Respiratory (2020-2028) ($MN) 
49 Global Blow Fill Seal (BFS) Technology Market Outlook, By Biologics (2020-2028) ($MN) 
50 Global Blow Fill Seal (BFS) Technology Market Outlook, By Injectables (2020-2028) ($MN) 
51 Global Blow Fill Seal (BFS) Technology Market Outlook, By Medical Devices (2020-2028) ($MN)
52 Global Blow Fill Seal (BFS) Technology Market Outlook, By Ophthalmic (2020-2028) ($MN) 
53 Global Blow Fill Seal (BFS) Technology Market Outlook, By Vaccine (2020-2028) ($MN) 
54 Global Blow Fill Seal (BFS) Technology Market Outlook, By Wound Care (2020-2028) ($MN) 
55 Global Blow Fill Seal (BFS) Technology Market Outlook, By Energy & Power (2020-2028) ($MN)
56 Global Blow Fill Seal (BFS) Technology Market Outlook, By Electronics (2020-2028) ($MN) 
57 Global Blow Fill Seal (BFS) Technology Market Outlook, By Agriculture (2020-2028) ($MN) 
          
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

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