Flow Chemistry Market

Flow Chemistry Market

Flow Chemistry Market Forecasts to 2028 - Global Analysis By Technology (Photochemistry, Gas Based), Application (Polymers, Chemicals, Surgical), End User (Laboratories, Beverage, Agrochemicals) and By Geography

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4.6 (41 reviews)
Published: 2022 ID: SMRC21673

This report covers the impact of COVID-19 on this global market

Years Covered


Estimated Year Value (2022)

US $88.70 MN

Projected Year Value (2028)

US $186.84 MN

CAGR (2022 - 2028)


Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

Asia Pacific

Highest Growing Market

North America

According to Stratistics MRC, the Global Flow Chemistry Market is accounted for $88.70 million in 2022 and is expected to reach $186.84 million by 2028 growing at a CAGR of 13.2% during the forecast period. Flow chemistry is a technology in which a chemical reaction is run in a continuously flowing stream rather than in batch production and this technique has also enabled many chemical processes to be more efficient, safer, faster, cleaner, and cheaper. It is expected to resolve difficulties related to the size of distribution of particles, irreproducibility of size, and the quality of the nanomaterial.

Many of the benefits of flow chemistry come down to the reactors’ high surface area to volume ratio, Lévesque explains. Temperature changes are much easier to manage, eliminating cryogenic conditions that are hard to implement in large scale industrial reactors. Mixing is also much better. This typically provides better reaction control, which in turn can lead to higher yields and more sustainable processes. In making potential respiratory drug gefapixant, for example, Merck used a flow process to tightly control the reaction, improving its safety and the sustainability. As an example of simplifying a difficult process, Baumann cites a Matteson reaction used by Thermo Fisher Scientific. This involves removing a hydrogen atom from dichloromethane and replacing it with a lithium ion, then reacting it with an electrophile. To make the intermediate at batch scale involves cooling to –100°C. In flow processes the time an intermediate exists for is determined by the flow rate, which meant Thermo Fisher scientists only had to cool to –80°C. ‘That allows you to reproducibly generate the lithiated dichloromethane and quench it within half a minute before it can decompose.

Market Dynamics:


Increasing demand from pharmaceutical sector

The flow chemistry technology is being extensively employed in the pharmaceutical sector for its role in drug discovery, chemical process development and production of pharmaceutical drugs. Flow chemistry was introduced in the pharmaceutical sector in the early 2000s when researchers began developing systems for Active Pharmaceutical Ingredients (APIs) and intermediate synthesis. For almost a decade, flow chemistry has grown from an innovative synthesis concept to a versatile & powerful platform for the continuous manufacturing of APIs with a small manufacturing footprint, high productivity, and reduced waste & cost.


Requirement of specialised equipment

The disadvantage of flow chemistry is that more specialised equipment is required. The choice and cost of this equipment can make flow chemistry difficult to access. Since flow chemistry is part-engineering and part-chemistry there isn’t always the broad skillset required to make the leap to this very powerful technique. For example, if reaction tubing clogs, heterogeneous mixtures may be a little more difficult to process.


Technological advancements

With rising concerns regarding climate change and the hazardous applications of chemical reactions on the environment, flow chemistry is emerging as an eco-friendly and safe chemical technology. The use of flow reactors has proven to be effective in the large-scale production of biodiesel from waste. This will provide immense business opportunities to the vendors of the market in concern during the forecast period.

The plug flow reactors (PFR) segment is expected to be the largest during the forecast period

Plug flow reactors are highly suitable for rapid reactions and large capacity processes which is expected to increase its utilization in pharmaceutical and chemical manufacturing. These reactors provide huge opportunities for scaling up the production process at a low cost which is anticipated to have a positive impact on market growth in the forthcoming years.

The chemicals segment is expected to have the highest CAGR during the forecast period

Increasing demand for specialty & fine chemicals coupled with a rising focus on scaling up the production processes is expected to propel the demand for flow reactors in the chemical industry. Flow chemistry aids in reducing the number of steps and reaction rate which is likely to have a positive impact on the market growth.

Region with largest share:

Asia Pacific is projected to hold the largest market share owing to the rising health awareness, leading to increasing demand for generic drugs, is expected to propel the utilization of flow chemistry processes to scale up the manufacturing of generic drugs in the region. Furthermore, increasing investment in the chemical and pharmaceutical industry especially in India, China, and Japan is expected to benefit the market over the forecast period. For example, Syrris launched its automatic reagent injector in Asia. The product provides high throughput due to automatic sample injection through two independent channels and can synthesize complex matrix libraries.

Region with highest CAGR:

North America is projected to have the highest CAGR as U.S is the largest market for flow chemistry in North America. High chemical and pharmaceutical manufacturing coupled with increasing investment by the petrochemical manufacturers is expected to play a key role in driving the regional demand in the forthcoming years.

Key players in the market:

Some of the key players profiled in the Flow Chemistry Market include Biotage AB, Syrris Ltd., Vapourtec Ltd., ThalesNano Inc., Uniqsis Ltd., Chemtrix BV, Cambridge Reactor Design Ltd., PDC Machines Inc., CEM Corporation, Future Chemistry Holding BV, Corning Incorporated and Lonza Group Ltd.

Key developments:

In February 2016: Chemtrix appointed Central Scientific Commerce as its distributor in Japan in order to facilitate direct reactor sales and customer support to the R&D and production communities in the economy.

In November 2015: Biotage AB opened a demonstration & application lab in Sweden which facilitated further research across all the product lines of the company.

Technologies Covered:
• Microwave Irradiation
• Photochemistry Based
• Gas Based

Reactors Covered:
• Continuous Flow Reactors
• Plug Flow Reactors (PFR)
• Microwave System
• Continuous Stirred Tank Reactors (CSTR)
• Meso Reactor
• Micro Reactor Systems (MRT)

Applications Covered:
• Polymers
• Chemicals
• Surgical
• Pharmaceuticals
• Bio fuels
• Agrochemicals
• Petrochemicals
• Nutraceutical Firms

End Users Covered:
• Analytical Laboratories
• Academics and Research Institutes
• Perfume & Fragrance Industries
• Agriculture and Environmental
• Food and Beverage

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025 and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions

3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Technology Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19

4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 Global Flow Chemistry Market, By Technology
5.1 Introduction
5.2 Microwave Irradiation
5.3 Photochemistry Based
5.4 Gas Based

6 Global Flow Chemistry Market, By Reactor
6.1 Introduction
6.2 Continuous Flow Reactors
6.3 Plug Flow Reactors (PFR)
6.4 Microwave System
6.5 Continuous Stirred Tank Reactors (CSTR)
6.6 Meso Reactor
6.7 Micro Reactor Systems (MRT)
6.7.1 Capillary-Based
6.7.2 Micro Structured
6.7.3 Chip-Based

7 Global Flow Chemistry Market, By Application
7.1 Introduction
7.2 Polymers
7.3 Chemicals
7.4 Surgical
7.5 Pharmaceuticals
7.6 Bio fuels
7.7 Agrochemicals
7.8 Petrochemicals
7.9 Nutraceutical Firms

8 Global Flow Chemistry Market, By End User
8.1 Introduction
8.2 Analytical Laboratories
8.3 Academics and Research Institutes
8.4 Perfume & Fragrance Industries
8.5 Agriculture and Environmental
8.6 Food and Beverage

9 Global Flow Chemistry Market, By Geography
9.1 Introduction
9.2 North America
9.2.1 US
9.2.2 Canada
9.2.3 Mexico
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 Italy
9.3.4 France
9.3.5 Spain
9.3.6 Rest of Europe
9.4 Asia Pacific
9.4.1 Japan
9.4.2 China
9.4.3 India
9.4.4 Australia
9.4.5 New Zealand
9.4.6 South Korea
9.4.7 Rest of Asia Pacific
9.5 South America
9.5.1 Argentina
9.5.2 Brazil
9.5.3 Chile
9.5.4 Rest of South America
9.6 Middle East & Africa
9.6.1 Saudi Arabia
9.6.2 UAE
9.6.3 Qatar
9.6.4 South Africa
9.6.5 Rest of Middle East & Africa

10 Key Developments
10.1 Agreements, Partnerships, Collaborations and Joint Ventures
10.2 Acquisitions & Mergers
10.3 New Product Launch
10.4 Expansions
10.5 Other Key Strategies

11 Company Profiling
11.1 Biotage AB
11.2 Syrris Ltd.
11.3 Vapourtec Ltd.
11.4 ThalesNano Inc.
11.5 Uniqsis Ltd.
11.6 Chemtrix BV
11.7 Cambridge Reactor Design Ltd.
11.8 PDC Machines Inc.
11.9 CEM Corporation
11.10 Future Chemistry Holding BV
11.11 Corning Incorporated
11.12 Lonza Group Ltd.

List of Tables
1 Global Flow Chemistry Market Outlook, By Region (2020-2028) ($MN)
2 Global Flow Chemistry Market Outlook, By Technology (2020-2028) ($MN)
3 Global Flow Chemistry Market Outlook, By Microwave Irradiation (2020-2028) ($MN)
4 Global Flow Chemistry Market Outlook, By Photochemistry Based (2020-2028) ($MN)
5 Global Flow Chemistry Market Outlook, By Gas Based (2020-2028) ($MN)
6 Global Flow Chemistry Market Outlook, By Reactor (2020-2028) ($MN)
7 Global Flow Chemistry Market Outlook, By Continuous Flow Reactors (2020-2028) ($MN)
8 Global Flow Chemistry Market Outlook, By Plug Flow Reactors (PFR) (2020-2028) ($MN)
9 Global Flow Chemistry Market Outlook, By Microwave System (2020-2028) ($MN)
10 Global Flow Chemistry Market Outlook, By Continuous Stirred Tank Reactors (CSTR) (2020-2028) ($MN)
11 Global Flow Chemistry Market Outlook, By Meso Reactor (2020-2028) ($MN)
12 Global Flow Chemistry Market Outlook, By Micro Reactor Systems (MRT) (2020-2028) ($MN)
13 Global Flow Chemistry Market Outlook, By Capillary-Based (2020-2028) ($MN)
14 Global Flow Chemistry Market Outlook, By Micro Structured (2020-2028) ($MN)
15 Global Flow Chemistry Market Outlook, By Chip-Based (2020-2028) ($MN)
16 Global Flow Chemistry Market Outlook, By Application (2020-2028) ($MN)
17 Global Flow Chemistry Market Outlook, By Polymers (2020-2028) ($MN)
18 Global Flow Chemistry Market Outlook, By Chemicals (2020-2028) ($MN)
19 Global Flow Chemistry Market Outlook, By Surgical (2020-2028) ($MN)
20 Global Flow Chemistry Market Outlook, By Pharmaceuticals (2020-2028) ($MN)
21 Global Flow Chemistry Market Outlook, By Bio fuels (2020-2028) ($MN)
22 Global Flow Chemistry Market Outlook, By Agrochemicals (2020-2028) ($MN)
23 Global Flow Chemistry Market Outlook, By Petrochemicals (2020-2028) ($MN)
24 Global Flow Chemistry Market Outlook, By Nutraceutical Firms (2020-2028) ($MN)
25 Global Flow Chemistry Market Outlook, By End User (2020-2028) ($MN)
26 Global Flow Chemistry Market Outlook, By Analytical Laboratories (2020-2028) ($MN)
27 Global Flow Chemistry Market Outlook, By Academics and Research Institutes (2020-2028) ($MN)
28 Global Flow Chemistry Market Outlook, By Perfume & Fragrance Industries (2020-2028) ($MN)
29 Global Flow Chemistry Market Outlook, By Agriculture and Environmental (2020-2028) ($MN)
30 Global Flow Chemistry Market Outlook, By Food and Beverage (2020-2028) ($MN)

Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.

Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.

For more details about research methodology, kindly write to us at info@strategymrc.com

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