Immunoglobulin Market

Immunoglobulin Market

Immunoglobulin Market Forecasts to 2028 - Global Analysis By Product (Immunoglobulin G (IgG), Immunoglobulin A (IgA), Immunoglobulin M (IgM), Immunoglobulin E (IgE) and Immunoglobulin D (IgD)), Form (Liquid and Lyophilized), Mode Of Delivery (Intravenous and Subcutaneous), Application (Primary Immunodeficiency (PI), Secondary Immunodeficiency (SID), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Other Applications, End User (Hospitals, Clinics and Homecare) and By Geography

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Published: 2023 ID: SMRC22651

This report covers the impact of COVID-19 on this global market

Years Covered


Estimated Year Value (2022)

US $15.13 BN

Projected Year Value (2028)

US $27.55 BN

CAGR (2022 - 2028)


Regions Covered

North America, Europe, Asia Pacific, South America, and Middle East & Africa

Countries Covered

US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa

Largest Market

North America

Highest Growing Market

Asia Pacific

According to Stratistics MRC, the Global Immunoglobulins Market is accounted for $15.13 billion in 2022 and is expected to reach $27.55 billion by 2028 growing at a CAGR of 10.5% during the forecast period. Immunoglobulins refers to a class of polymers with heat distortion temperatures higher than 150 degrees Celsius. These materials have excellent properties like the ability to withstand extremely high temperatures, superior strength and rigidity, increased durability, and high chemical resistance. One of the main market drivers is the expanding use of 3D printing high-performance plastic in the manufacturing industry. A good strength-to-weight ratio in 3D printing plastic balances the heavy components in the products.

According to the National Clinical Trial (NCT) Registry, as of March 9th, 2021, in the United States, there were around 50 immunoglobulin-based ongoing clinical trials across different phases of development, which shows a positive impact on the market.

Market Dynamics:


Increasing prevalence of immunological disorders

The market share for immunoglobulins has grown as a result of an increase in immunological disorders that have caused people to seek out cutting-edge medical treatment. For off-label purposes, intravenous and subcutaneous immunoglobulin use has significantly increased. Global healthcare systems are extremely concerned about the growing senior population as well as the rising frequency of immunodeficiency and neurological illnesses. Thus, there is a rise in demand for novel intravenous immunoglobulin therapies due to increased awareness and the need to ensure effective treatment, which is anticipated to drive market growth.


High cost associated with the therapy

The rising prevalence of immunological disorders and the availability of more drugs for their treatment are driving the market's expansion. However, the expensive nature of this therapy is severely restricting its uptake. The low insurance coverage and high price of plasma products in South Africa are limiting their uptake. Therefore, it is anticipated that higher costs brought on by insufficient reimbursement policies will limit the adoption of these products among the general public worldwide.


Rapid urbanization

Fast food consumption is increasing among people as a result of rapid urbanization and busy schedules. One of the primary factors driving market growth is an increase in patients suffering from diseases such as multiple myeloma, Waldenstrom macroglobulinemia, and autoimmune disorders. Additionally, rising interest in personalized medicine and increased awareness of the importance of early diagnosis are other factors driving market expansion.


Lack of skilled professionals

Immunoglobulin development is a time-consuming, expensive process that calls for substantial financial outlays, clinical trial experience, quality control measures, and technical capabilities. Due to the strict regulations imposed by the regulators, immunoglobulin manufacturers are required to invest in clinical trials and post-approval safety monitoring programs. Both qualified healthcare workers and those with the necessary training to administer immunoglobulin therapies are in short supply. Additionally, there aren't many concerns in the medical community about the safety of this therapy. Therefore, a lack of knowledge and expertise may restrain market expansion.

Covid-19 Impact

The COVID-19 had a sizable effect on the market's expansion. Effective therapies for the treatment of patients with COVID-19 infection were urgently needed due to the rise in cases and high mortality that resulted from it. Immunoglobulin therapy for COVID-19 infection may be useful in managing the condition. The market participants have concentrated on the product's development and research. For instance, in May 2020, the US Food and Drug Administration (FDA) approved Octapharma USA's application for an investigational new drug (IND) to test the efficacy and safety of treating COVID-19 patients with severe disease progression with Octagam 10% therapy. The trial is scheduled to take place in a phase three clinical trial. As a result, COVID-19 had a major influence on the market's expansion.

The liquid segment is expected to be the largest during the forecast period

During the forecast period, the liquid segment is anticipated to account for the largest share of the market for immunoglobulins. The widespread adoption of liquid immunoglobulin therapy across the globe is largely attributed to the rising prevalence of autoimmune disorders and the growing range of liquid immunoglobulin therapy options. This, coupled with the cost-effectiveness of this drug form and no requirement for further dilution, is another factor contributing to the highest demand and adoption of liquid throughout the projection period, which is driving the segment expansion.

The intravenous segment is expected to have the highest CAGR during the forecast period

Due to the rising preference for administering immunoglobulins through intravenous mode, this segment is anticipated to register the highest CAGR during the projected timeframe. An injection or infusion method of drug administration into the vein through a needle or tube is referred to as an intravenous mode of delivery. The main drivers of the segment's growth are the rising number of strategic initiatives involving intravenous immunoglobulin and the rising volume of R&D projects that have received regulatory authority approval. The segment is expanding as a result of more and more drug approvals.

Region with largest share:

The largest share of the immunoglobulin market was accounted for by North America during the forecast period. This is because immunoglobulin has received an increasing number of FDA approvals in the United States. Due to the high prevalence of neurological, immunological, and other disorders, an increase in the local supply of intravenous immunoglobulin products, significant reimbursement coverage, and the presence of major market players. The region's medical innovations, rising consumer awareness of their own health, and new developments in antibody therapy are propelling market growth.

Region with highest CAGR:

Due to rising healthcare reforms, government initiatives to make expensive IG therapies more affordable, and rising healthcare costs, Asia Pacific is predicted to grow at the highest CAGR during the forecast period. Countries like Japan, India, and other Southeast Asian nations currently consume significantly fewer immunoglobulins per person than the United States. However, the increasing number of patients suffering from immunodeficiencies and the availability of reimbursement for these drugs are poised to drive consumption during the forecast period.

Key players in the market

Some of the key players profiled in the Immunoglobulins Market include ADMA Biologics, Inc., Baxter international Inc., Bio Products Laboratory Ltd., Biotest AG., China Biologic Products Holdings, Inc., Coram LLC, CSL Limited, Cygnus Technologies, Gentian Diagnostics AS, Green Cross Corp, Grifols, S.A., Haffkine Bio-Pharmaceutical Corporation Ltd, Hualan Biological Engineering Inc., J. Mitra & Co. Pvt. Ltd, Kamada Pharmaceuticals, Kedrion Biopharma Inc., LFB Group Mabtech, Momenta Pharmaceuticals, Octapharma AG, Option Care Enterprises, Inc., Shanghai RAAS and Takeda Pharmaceutical Company Limited.

Key Developments:

In August 2022, Argenx received marketing authorization for Argenx from the Europe Commission. It will be used to cure adult patients with widespread myasthenia gravis treated against acetylcholine receptors that are anti-acetylcholine receptor antibody positive.

In March 2022, Grifols received approval by several European Union member state health authorities as well as by the United Kingdom for XEMBIFY. It is an innovative 20% subcutaneous immunoglobulin (SCIG) that has been approved to treat primary and selected secondary immunodeficiencies.

In January 2022, the European Union expanded the indication for cutaquig by Octapharma. It is a human immunoglobulin for subcutaneous administration. The expanded indication covers patients with any type of secondary immunodeficiency who need immunoglobulin replacement therapy.

Products Covered:
• Immunoglobulin G (IgG)
• Immunoglobulin A (IgA)
• Immunoglobulin M (IgM)
• Immunoglobulin E (IgE)
• Immunoglobulin D (IgD)

Forms Covered:
• Liquid
• Lyophilized

Technologies Covered:
• Focused Deposition Modelling
• Selective Laser Sintering

Mode Of Deliveries Covered:
• Intravenous
• Subcutaneous

Applications Covered:
• Primary Immunodeficiency (PI)
• Secondary Immunodeficiency (SID)
• Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
• Guillain Barré Syndrome
• Immunodeficiency Diseases
• Chronic Lymphocytic Leukaemia
• Specific Antibody Deficiency
• Inflammatory Myopathies
• Immune Thrombocytopenic Purpura (ITP)
• Multifocal Motor Neuropathy (MMN)
• Other Applications

End Users Covered:
• Hospitals
• Clinics
• Homecare

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions

3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19

4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 Global Immunoglobulin Market, By Product
5.1 Introduction
5.2 Immunoglobulin G (IgG)
5.3 Immunoglobulin A (IgA)
5.4 Immunoglobulin M (IgM)
5.5 Immunoglobulin E (IgE)
5.6 Immunoglobulin D (IgD)

6 Global Immunoglobulin Market, By Form
6.1 Introduction
6.2 Liquid
6.3 Lyophilized

7 Global Immunoglobulin Market, By Mode Of Delivery
7.1 Introduction
7.2 Intravenous
7.2.1 5% Concentration
7.2.2 10% Concentration
7.2.3 Other Intravenous Modes
7.3 Subcutaneous
7.3.1 16.5% Concentration
7.3.2 20% Concentration
7.3.3 Other Subcutaneous Modes

8 Global Immunoglobulin Market, By Application
8.1 Introduction
8.2 Primary Immunodeficiency (PI)
8.3 Secondary Immunodeficiency (SID)
8.4 Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
8.5 Guillain Barré Syndrome
8.6 Immunodeficiency Diseases
8.7 Chronic Lymphocytic Leukaemia
8.8 Specific Antibody Deficiency
8.9 Inflammatory Myopathies
8.10 Immune Thrombocytopenic Purpura (ITP)
8.11 Multifocal Motor Neuropathy (MMN)
8.12 Other Applications

9 Global Immunoglobulin Market, By End User
9.1 Introduction
9.2 Hospitals
9.3 Clinics
9.4 Homecare

10 Global Immunoglobulin Market, By Geography
10.1 Introduction
10.2 North America
10.2.1 US
10.2.2 Canada
10.2.3 Mexico
10.3 Europe
10.3.1 Germany
10.3.2 UK
10.3.3 Italy
10.3.4 France
10.3.5 Spain
10.3.6 Rest of Europe
10.4 Asia Pacific
10.4.1 Japan
10.4.2 China
10.4.3 India
10.4.4 Australia
10.4.5 New Zealand
10.4.6 South Korea
10.4.7 Rest of Asia Pacific
10.5 South America
10.5.1 Argentina
10.5.2 Brazil
10.5.3 Chile
10.5.4 Rest of South America
10.6 Middle East & Africa
10.6.1 Saudi Arabia
10.6.2 UAE
10.6.3 Qatar
10.6.4 South Africa
10.6.5 Rest of Middle East & Africa

11 Key Developments
11.1 Agreements, Partnerships, Collaborations and Joint Ventures
11.2 Acquisitions & Mergers
11.3 New Product Launch
11.4 Expansions
11.5 Other Key Strategies

12 Company Profiling
12.1 ADMA Biologics, Inc.
12.2 Baxter international Inc.
12.3 Bio Products Laboratory Ltd.
12.4 Biotest AG.
12.5 China Biologic Products Holdings, Inc.
12.6 Coram LLC
12.7 CSL Limited
12.8 Cygnus Technologies
12.9 Gentian Diagnostics AS
12.11 Grifols, S.A.
12.13 Hualan Biological Engineering Inc.
12.14 J. Mitra & Co. Pvt. Ltd
12.15 Kamada Pharmaceuticals
12.16 Kedrion Biopharma Inc.
12.17 LFB Group
12.18 Mabtech
12.19 Momenta Pharmaceuticals
12.20 Octapharma AG
12.21 Option Care Enterprises, Inc.
12.22 Shanghai RAAS
12.23 Takeda Pharmaceutical Company Limited

List of Tables
1 Global Immunoglobulin Market Outlook, By Region (2020-2028) ($MN)
2 Global Immunoglobulin Market Outlook, By Product (2020-2028) ($MN)
3 Global Immunoglobulin Market Outlook, By Immunoglobulin G (IgG) (2020-2028) ($MN)
4 Global Immunoglobulin Market Outlook, By Immunoglobulin A (IgA) (2020-2028) ($MN)
5 Global Immunoglobulin Market Outlook, By Immunoglobulin M (IgM) (2020-2028) ($MN)
6 Global Immunoglobulin Market Outlook, By Immunoglobulin E (IgE) (2020-2028) ($MN)
7 Global Immunoglobulin Market Outlook, By Immunoglobulin D (IgD) (2020-2028) ($MN)
8 Global Immunoglobulin Market Outlook, By Form (2020-2028) ($MN)
9 Global Immunoglobulin Market Outlook, By Liquid (2020-2028) ($MN)
10 Global Immunoglobulin Market Outlook, By Lyophilized (2020-2028) ($MN)
11 Global Immunoglobulin Market Outlook, By Mode Of Delivery (2020-2028) ($MN)
12 Global Immunoglobulin Market Outlook, By Intravenous (2020-2028) ($MN)
13 Global Immunoglobulin Market Outlook, By 5% Concentration (2020-2028) ($MN)
14 Global Immunoglobulin Market Outlook, By 10% Concentration (2020-2028) ($MN)
15 Global Immunoglobulin Market Outlook, By Other Intravenous Modes (2020-2028) ($MN)
16 Global Immunoglobulin Market Outlook, By Subcutaneous (2020-2028) ($MN)
17 Global Immunoglobulin Market Outlook, By 16.5% Concentration (2020-2028) ($MN)
18 Global Immunoglobulin Market Outlook, By 20% Concentration (2020-2028) ($MN)
19 Global Immunoglobulin Market Outlook, By Other Subcutaneous Modes (2020-2028) ($MN)
20 Global Immunoglobulin Market Outlook, By Application (2020-2028) ($MN)
21 Global Immunoglobulin Market Outlook, By Primary Immunodeficiency (PI) (2020-2028) ($MN)
22 Global Immunoglobulin Market Outlook, By Secondary Immunodeficiency (SID) (2020-2028) ($MN)
23 Global Immunoglobulin Market Outlook, By Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (2020-2028) ($MN)
24 Global Immunoglobulin Market Outlook, By Guillain Barré Syndrome (2020-2028) ($MN)
25 Global Immunoglobulin Market Outlook, By Immunodeficiency Diseases (2020-2028) ($MN)
26 Global Immunoglobulin Market Outlook, By Chronic Lymphocytic Leukaemia (2020-2028) ($MN)
27 Global Immunoglobulin Market Outlook, By Specific Antibody Deficiency (2020-2028) ($MN)
28 Global Immunoglobulin Market Outlook, By Inflammatory Myopathies (2020-2028) ($MN)
29 Global Immunoglobulin Market Outlook, By Immune Thrombocytopenic Purpura (ITP) (2020-2028) ($MN)
30 Global Immunoglobulin Market Outlook, By Multifocal Motor Neuropathy (MMN) (2020-2028) ($MN)
31 Global Immunoglobulin Market Outlook, By Other Applications (2020-2028) ($MN)
32 Global Immunoglobulin Market Outlook, By End User (2020-2028) ($MN)
33 Global Immunoglobulin Market Outlook, By Hospitals (2020-2028) ($MN)
34 Global Immunoglobulin Market Outlook, By Clinics (2020-2028) ($MN)
35 Global Immunoglobulin Market Outlook, By Homecare (2020-2028) ($MN)

Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

List of Figures


Research Methodology

We at Stratistics opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.

Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.

Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.

Data Mining

The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.

Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.

Data Analysis

From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:

  • Product Lifecycle Analysis
  • Competitor analysis
  • Risk analysis
  • Porters Analysis
  • PESTEL Analysis
  • SWOT Analysis

The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.

Data Validation

The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.

We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.

The data validation involves the primary research from the industry experts belonging to:

  • Leading Companies
  • Suppliers & Distributors
  • Manufacturers
  • Consumers
  • Industry/Strategic Consultants

Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.

For more details about research methodology, kindly write to us at

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