Liquid Biopsy Market
Liquid Biopsy Market Forecasts to 2032 - Global Analysis By Product Type (Assay Kits & Reagents, Instruments, Services, and Other Product Types), Biomarker Type, Sample Type, Technology, Application, End User and By Geography
|
Years Covered |
2024-2032 |
|
Estimated Year Value (2025) |
US $13447.02 MN |
|
Projected Year Value (2032) |
US $32628.51 MN |
|
CAGR (2025-2032) |
13.5% |
|
Regions Covered |
North America, Europe, Asia Pacific, South America, and Middle East & Africa |
|
Countries Covered |
US, Canada, Mexico, Germany, UK, Italy, France, Spain, Japan, China, India, Australia, New Zealand, South Korea, Rest of Asia Pacific, South America, Argentina, Brazil, Chile, Middle East & Africa, Saudi Arabia, UAE, Qatar, and South Africa |
|
Largest Market |
Asia Pacific |
|
Highest Growing Market |
North America |
According to Stratistics MRC, the Global Liquid Biopsy Market is accounted for $13447.02 million in 2025 and is expected to reach $32628.51 million by 2032 growing at a CAGR of 13.5% during the forecast period. Liquid biopsy is a non-invasive diagnostic technique that detects cancer and other diseases by analyzing biomarkers such as circulating tumor DNA (ctDNA), RNA, or exosomes present in body fluids like blood or urine. It offers a real-time snapshot of disease progression, enabling early detection, monitoring of treatment response, and detection of recurrence. Liquid biopsy provides a safer, quicker alternative to traditional tissue biopsies, enhancing patient care and personalized treatment strategies.
According to the International Agency for Research on Cancer (IARC), over 20.7 million new cancer cases are expected in 2023.
Market Dynamics:
Driver:
Increased preference for personalized medicine
The growing shift toward personalized medicine is a major catalyst for the expansion of the liquid biopsy market. As oncology care becomes more tailored, clinicians increasingly rely on minimally invasive tools like liquid biopsy to guide treatment decisions. These tests enable real-time monitoring of tumor dynamics, helping physicians adjust therapies based on individual molecular profiles. The ability to detect actionable mutations through circulating biomarkers supports the use of targeted therapies, improving patient outcomes. This rising demand for precision diagnostics is accelerating the adoption of liquid biopsy across research and clinical settings.
Restraint:
Limited clinical validation
Many liquid biopsy tests, particularly those detecting early-stage cancers or rare mutations, lack comprehensive, large-scale clinical trials to confirm their sensitivity, specificity, and overall reliability. Without robust validation, healthcare providers may hesitate to trust these tests for critical decisions such as diagnosis, treatment planning, or monitoring. This uncertainty also impacts regulatory approvals and insurance reimbursements, further delaying market penetration. To gain broader acceptance, more longitudinal studies and peer-reviewed evidence are essential to establish clinical utility across diverse patient populations.
Opportunity:
Advancements in genomics and next-generation sequencing (NGS)
NGS technologies enable high-throughput, accurate, and cost-effective analysis of circulating tumor DNA (ctDNA), exosomes, and other biomarkers from blood samples. These innovations allow for the detection of genetic mutations, copy number variations, and epigenetic changes with unprecedented sensitivity and specificity. As NGS becomes more accessible and integrated into clinical workflows, it enhances the ability to diagnose cancer early, monitor disease progression, and guide personalized treatment. Continuous improvements in sequencing speed, data analytics, and bioinformatics are further accelerating the clinical adoption of liquid biopsy.
Threat:
Complexity in data interpretation
The increasing complexity of genomic data generated by liquid biopsy tests poses a significant challenge. Interpreting multi-gene panels and distinguishing clinically relevant mutations from benign variants requires advanced bioinformatics expertise. Inconsistent reporting standards and lack of consensus on variant classification can lead to confusion among clinicians. This complexity may delay treatment decisions or result in suboptimal therapy selection. Smaller labs and healthcare providers may lack the infrastructure to manage and analyze such data effectively. Without streamlined interpretation tools and standardized guidelines, the full potential of liquid biopsy may remain underutilized.
Covid-19 Impact:
The COVID-19 pandemic had a dual impact on the liquid biopsy market. Initially, diagnostic delays and reduced hospital visits led to a temporary decline in cancer screening and monitoring procedures. However, the need for non-invasive, remote-friendly testing solutions brought renewed attention to liquid biopsy. As healthcare systems adapted, liquid biopsy emerged as a safer alternative to tissue biopsies, especially for immunocompromised patients. Post-pandemic, the market witnessed accelerated adoption driven by increased awareness of early detection and real-time monitoring.
The instruments segment is expected to be the largest during the forecast period
The instruments segment is expected to account for the largest market share during the forecast period, due to the critical role of platforms such as NGS systems, digital PCR, and microfluidic devices in enabling accurate biomarker detection. These instruments form the backbone of liquid biopsy workflows, supporting both research and clinical applications. Continuous innovation in sequencing speed, throughput, and automation is enhancing test efficiency and scalability. As demand for high-sensitivity diagnostics grows, investment in advanced instrumentation is expected to rise.
The specialty clinics segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the specialty clinics segment is predicted to witness the highest growth rate. These clinics are increasingly adopting liquid biopsy for cancer screening, therapy selection, and recurrence monitoring. Their focused expertise and streamlined workflows make them ideal settings for implementing advanced diagnostics. As awareness of personalized medicine grows, patients are turning to specialty centers for tailored care. Additionally, partnerships between diagnostic companies and specialty clinics are expanding access to cutting-edge tests.
Region with largest share:
During the forecast period, the Asia Pacific region is expected to hold the largest market share, driven by rising cancer incidence, expanding healthcare infrastructure, and increasing government investment in precision medicine. Countries like China, India, and Japan are witnessing rapid adoption of advanced diagnostics, including liquid biopsy. Local players are also entering the market with cost-effective solutions tailored to regional needs. Public-private partnerships and favorable regulatory reforms are further accelerating market penetration.
Region with highest CAGR:
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, owing to the region benefits from a well-established healthcare system, strong R&D ecosystem, and early adoption of genomic technologies. Regulatory approvals for liquid biopsy-based companion diagnostics are increasing, boosting clinical confidence. Additionally, rising demand for non-invasive cancer screening and monitoring is fueling test volumes. Strategic collaborations between biotech firms, academic institutions, and healthcare providers are driving innovation.
Key players in the market
Some of the key players in Liquid Biopsy Market include F. Hoffmann-La Roche Ltd., Menarini Silicon Biosystems, Guardant Health Inc., Freenome Holdings, Inc., Illumina Inc., Biocept, Inc., Thermo Fisher Scientific Inc., ANGLE plc, Exact Sciences Corporation, Caris Life Sciences, Natera Inc., NeoGenomics Laboratories, QIAGEN N.V., Lucence Health Inc., Bio-Rad Laboratories Inc., Foundation Medicine, Inc., Epigenomics AG, Johnson & Johnson Services Inc., Myriad Genetics, Inc., and Sysmex Corporation.
Key Developments:
In May 2025, Roche announced a strategic collaboration with Broad Clinical Labs to develop and pilot groundbreaking applications using Roche’s recently unveiled next-generation sequencing (NGS) Sequencing By Expansion (SBX) technology. This collaboration will focus on harnessing the power of the SBX technology to transform clinical genomics and biomedical discovery. It will also aim to establish the SBX technology as a routine offering for fast, scalable sequencing for Broad Clinical Lab’s research community.
In July 2022, Menarini Silicon Biosystems Inc, announced at the American Association for Clinical Chemistry (AACC) Annual Scientific Meeting & Clinical Lab Expo that they have entered into a commercial agreement for the exclusive distribution of the CHORUS TRIO immunometric assay system in the United States of America.
Product Types Covered:
• Assay Kits & Reagents
• Instruments
• Services
• Other Product Types
Biomarker Types Covered:
• Circulating Tumor Cells (CTCs)
• Circulating Tumor DNA (ctDNA)
• Exosomes and Extracellular Vesicles
• Cell-Free DNA (cfDNA)
• Cell-Free RNA (cfRNA)
• Circulating Proteins
• Other Biomarker Types
Sample Types Covered:
• Blood
• Saliva
• Urine
• Fecal-Based Sampling
• Other Body Fluids
Technologies Covered:
• Next-Generation Sequencing (NGS)
• Beads, Emulsion, Amplification, and Magnetics (BEAMing)
• Polymerase Chain Reaction (PCR)
• Digital Droplet PCR (ddPCR)
• Other Technologies
Applications Covered:
• Cancer Applications
• Non-Cancer Applications
• Other Applications
End Users Covered:
• Hospitals and Physician Laboratories
• Diagnostic Laboratories
• Academic and Research Institutes
• Biopharmaceutical and Biotechnology Companies
• Reference Laboratories
• Specialty Clinics
• Other End Users
Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa
What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2024, 2025, 2026, 2028, and 2032
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements
Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
o Comprehensive profiling of additional market players (up to 3)
o SWOT Analysis of key players (up to 3)
• Regional Segmentation
o Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances
Table of Contents
1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Technology Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Liquid Biopsy Market, By Product Type
5.1 Introduction
5.2 Assay Kits & Reagents
5.3 Instruments
5.4 Services
5.4.1 Clinical Testing Services
5.4.2 Biomarker Discovery Services
5.4.3 Customized Assay Development
5.4.4 Data Analysis and Bioinformatics Software
5.5 Other Product Types
6 Global Liquid Biopsy Market, By Biomarker Type
6.1 Introduction
6.2 Circulating Tumor Cells (CTCs)
6.3 Circulating Tumor DNA (ctDNA)
6.4 Exosomes and Extracellular Vesicles
6.5 Cell-Free DNA (cfDNA)
6.6 Cell-Free RNA (cfRNA)
6.7 Circulating Proteins
6.8 Other Biomarker Types
7 Global Liquid Biopsy Market, By Sample Type
7.1 Introduction
7.2 Blood
7.3 Saliva
7.4 Urine
7.5 Fecal-Based Sampling
7.6 Other Body Fluids
8 Global Liquid Biopsy Market, By Technology
8.1 Introduction
8.2 Next-Generation Sequencing (NGS)
8.3 Beads, Emulsion, Amplification, and Magnetics (BEAMing)
8.4 Polymerase Chain Reaction (PCR)
8.5 Digital Droplet PCR (ddPCR)
8.6 Other Technologies
9 Global Liquid Biopsy Market, By Application
9.1 Introduction
9.2 Cancer Applications
9.2.1 Therapy Selection
9.2.2 Treatment Monitoring
9.2.3 Recurrence Monitoring
9.2.4 Early Cancer Screening
9.2.5 Prognosis
9.3 Non-Cancer Applications
9.3.1 Non-Invasive Prenatal Testing (NIPT)
9.3.2 Organ Transplantation
9.3.3 Infectious Disease Testing
9.3.4 Reproductive Health
9.4 Other Applications
10 Global Liquid Biopsy Market, By End User
10.1 Introduction
10.2 Hospitals and Physician Laboratories
10.3 Diagnostic Laboratories
10.4 Academic and Research Institutes
10.5 Biopharmaceutical and Biotechnology Companies
10.6 Reference Laboratories
10.7 Specialty Clinics
10.8 Other End Users
11 Global Liquid Biopsy Market, By Geography
11.1 Introduction
11.2 North America
11.2.1 US
11.2.2 Canada
11.2.3 Mexico
11.3 Europe
11.3.1 Germany
11.3.2 UK
11.3.3 Italy
11.3.4 France
11.3.5 Spain
11.3.6 Rest of Europe
11.4 Asia Pacific
11.4.1 Japan
11.4.2 China
11.4.3 India
11.4.4 Australia
11.4.5 New Zealand
11.4.6 South Korea
11.4.7 Rest of Asia Pacific
11.5 South America
11.5.1 Argentina
11.5.2 Brazil
11.5.3 Chile
11.5.4 Rest of South America
11.6 Middle East & Africa
11.6.1 Saudi Arabia
11.6.2 UAE
11.6.3 Qatar
11.6.4 South Africa
11.6.5 Rest of Middle East & Africa
12 Key Developments
12.1 Agreements, Partnerships, Collaborations and Joint Ventures
12.2 Acquisitions & Mergers
12.3 New Product Launch
12.4 Expansions
12.5 Other Key Strategies
13 Company Profiling
13.1 F. Hoffmann-La Roche Ltd.
13.2 Menarini Silicon Biosystems
13.3 Guardant Health Inc.
13.4 Freenome Holdings, Inc.
13.5 Illumina Inc.
13.6 Biocept, Inc.
13.7 Thermo Fisher Scientific Inc.
13.8 ANGLE plc
13.9 Exact Sciences Corporation
13.10 Caris Life Sciences
13.11 Natera Inc.
13.12 NeoGenomics Laboratories
13.13 QIAGEN N.V.
13.14 Lucence Health Inc.
13.15 Bio-Rad Laboratories Inc.
13.16 Foundation Medicine, Inc.
13.17 Epigenomics AG
13.18 Johnson & Johnson Services Inc.
13.19 Myriad Genetics, Inc.
13.20 Sysmex Corporation
List of Tables
1 Global Liquid Biopsy Market Outlook, By Region (2024-2032) ($MN)
2 Global Liquid Biopsy Market Outlook, By Product Type (2024-2032) ($MN)
3 Global Liquid Biopsy Market Outlook, By Assay Kits & Reagents (2024-2032) ($MN)
4 Global Liquid Biopsy Market Outlook, By Instruments (2024-2032) ($MN)
5 Global Liquid Biopsy Market Outlook, By Services (2024-2032) ($MN)
6 Global Liquid Biopsy Market Outlook, By Clinical Testing Services (2024-2032) ($MN)
7 Global Liquid Biopsy Market Outlook, By Biomarker Discovery Services (2024-2032) ($MN)
8 Global Liquid Biopsy Market Outlook, By Customized Assay Development (2024-2032) ($MN)
9 Global Liquid Biopsy Market Outlook, By Data Analysis and Bioinformatics Software (2024-2032) ($MN)
10 Global Liquid Biopsy Market Outlook, By Other Product Types (2024-2032) ($MN)
11 Global Liquid Biopsy Market Outlook, By Biomarker Type (2024-2032) ($MN)
12 Global Liquid Biopsy Market Outlook, By Circulating Tumor Cells (CTCs) (2024-2032) ($MN)
13 Global Liquid Biopsy Market Outlook, By Circulating Tumor DNA (ctDNA) (2024-2032) ($MN)
14 Global Liquid Biopsy Market Outlook, By Exosomes and Extracellular Vesicles (2024-2032) ($MN)
15 Global Liquid Biopsy Market Outlook, By Cell-Free DNA (cfDNA) (2024-2032) ($MN)
16 Global Liquid Biopsy Market Outlook, By Cell-Free RNA (cfRNA) (2024-2032) ($MN)
17 Global Liquid Biopsy Market Outlook, By Circulating Proteins (2024-2032) ($MN)
18 Global Liquid Biopsy Market Outlook, By Other Biomarker Types (2024-2032) ($MN)
19 Global Liquid Biopsy Market Outlook, By Sample Type (2024-2032) ($MN)
20 Global Liquid Biopsy Market Outlook, By Blood (2024-2032) ($MN)
21 Global Liquid Biopsy Market Outlook, By Saliva (2024-2032) ($MN)
22 Global Liquid Biopsy Market Outlook, By Urine (2024-2032) ($MN)
23 Global Liquid Biopsy Market Outlook, By Fecal-Based Sampling (2024-2032) ($MN)
24 Global Liquid Biopsy Market Outlook, By Other Body Fluids (2024-2032) ($MN)
25 Global Liquid Biopsy Market Outlook, By Technology (2024-2032) ($MN)
26 Global Liquid Biopsy Market Outlook, By Next-Generation Sequencing (NGS) (2024-2032) ($MN)
27 Global Liquid Biopsy Market Outlook, By Beads, Emulsion, Amplification, and Magnetics (BEAMing) (2024-2032) ($MN)
28 Global Liquid Biopsy Market Outlook, By Polymerase Chain Reaction (PCR) (2024-2032) ($MN)
29 Global Liquid Biopsy Market Outlook, By Digital Droplet PCR (ddPCR) (2024-2032) ($MN)
30 Global Liquid Biopsy Market Outlook, By Other Technologies (2024-2032) ($MN)
31 Global Liquid Biopsy Market Outlook, By Application (2024-2032) ($MN)
32 Global Liquid Biopsy Market Outlook, By Cancer Applications (2024-2032) ($MN)
33 Global Liquid Biopsy Market Outlook, By Therapy Selection (2024-2032) ($MN)
34 Global Liquid Biopsy Market Outlook, By Treatment Monitoring (2024-2032) ($MN)
35 Global Liquid Biopsy Market Outlook, By Recurrence Monitoring (2024-2032) ($MN)
36 Global Liquid Biopsy Market Outlook, By Early Cancer Screening (2024-2032) ($MN)
37 Global Liquid Biopsy Market Outlook, By Prognosis (2024-2032) ($MN)
38 Global Liquid Biopsy Market Outlook, By Non-Cancer Applications (2024-2032) ($MN)
39 Global Liquid Biopsy Market Outlook, By Non-Invasive Prenatal Testing (NIPT) (2024-2032) ($MN)
40 Global Liquid Biopsy Market Outlook, By Organ Transplantation (2024-2032) ($MN)
41 Global Liquid Biopsy Market Outlook, By Infectious Disease Testing (2024-2032) ($MN)
42 Global Liquid Biopsy Market Outlook, By Reproductive Health (2024-2032) ($MN)
43 Global Liquid Biopsy Market Outlook, By Other Applications (2024-2032) ($MN)
44 Global Liquid Biopsy Market Outlook, By End User (2024-2032) ($MN)
45 Global Liquid Biopsy Market Outlook, By Hospitals and Physician Laboratories (2024-2032) ($MN)
46 Global Liquid Biopsy Market Outlook, By Diagnostic Laboratories (2024-2032) ($MN)
47 Global Liquid Biopsy Market Outlook, By Academic and Research Institutes (2024-2032) ($MN)
48 Global Liquid Biopsy Market Outlook, By Biopharmaceutical and Biotechnology Companies (2024-2032) ($MN)
49 Global Liquid Biopsy Market Outlook, By Reference Laboratories (2024-2032) ($MN)
50 Global Liquid Biopsy Market Outlook, By Specialty Clinics (2024-2032) ($MN)
51 Global Liquid Biopsy Market Outlook, By Other End Users (2024-2032) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
List of Figures
RESEARCH METHODOLOGY
We at ‘Stratistics’ opt for an extensive research approach which involves data mining, data validation, and data analysis. The various research sources include in-house repository, secondary research, competitor’s sources, social media research, client internal data, and primary research.
Our team of analysts prefers the most reliable and authenticated data sources in order to perform the comprehensive literature search. With access to most of the authenticated data bases our team highly considers the best mix of information through various sources to obtain extensive and accurate analysis.
Each report takes an average time of a month and a team of 4 industry analysts. The time may vary depending on the scope and data availability of the desired market report. The various parameters used in the market assessment are standardized in order to enhance the data accuracy.
Data Mining
The data is collected from several authenticated, reliable, paid and unpaid sources and is filtered depending on the scope & objective of the research. Our reports repository acts as an added advantage in this procedure. Data gathering from the raw material suppliers, distributors and the manufacturers is performed on a regular basis, this helps in the comprehensive understanding of the products value chain. Apart from the above mentioned sources the data is also collected from the industry consultants to ensure the objective of the study is in the right direction.
Market trends such as technological advancements, regulatory affairs, market dynamics (Drivers, Restraints, Opportunities and Challenges) are obtained from scientific journals, market related national & international associations and organizations.
Data Analysis
From the data that is collected depending on the scope & objective of the research the data is subjected for the analysis. The critical steps that we follow for the data analysis include:
- Product Lifecycle Analysis
- Competitor analysis
- Risk analysis
- Porters Analysis
- PESTEL Analysis
- SWOT Analysis
The data engineering is performed by the core industry experts considering both the Marketing Mix Modeling and the Demand Forecasting. The marketing mix modeling makes use of multiple-regression techniques to predict the optimal mix of marketing variables. Regression factor is based on a number of variables and how they relate to an outcome such as sales or profits.
Data Validation
The data validation is performed by the exhaustive primary research from the expert interviews. This includes telephonic interviews, focus groups, face to face interviews, and questionnaires to validate our research from all aspects. The industry experts we approach come from the leading firms, involved in the supply chain ranging from the suppliers, distributors to the manufacturers and consumers so as to ensure an unbiased analysis.
We are in touch with more than 15,000 industry experts with the right mix of consultants, CEO's, presidents, vice presidents, managers, experts from both supply side and demand side, executives and so on.
The data validation involves the primary research from the industry experts belonging to:
- Leading Companies
- Suppliers & Distributors
- Manufacturers
- Consumers
- Industry/Strategic Consultants
Apart from the data validation the primary research also helps in performing the fill gap research, i.e. providing solutions for the unmet needs of the research which helps in enhancing the reports quality.
For more details about research methodology, kindly write to us at info@strategymrc.com
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